Ivan Adzhubei
Ivan Adzhubei
Brigham & Women's Hospital / Harvard Medical School
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A method and server for predicting damaging missense mutations
IA Adzhubei, S Schmidt, L Peshkin, VE Ramensky, A Gerasimova, P Bork, ...
Nature methods 7 (4), 248-249, 2010
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
ENCODE Project Consortium
nature 447 (7146), 799, 2007
Predicting functional effect of human missense mutations using PolyPhen‐2
I Adzhubei, DM Jordan, SR Sunyaev
Current protocols in human genetics 76 (1), 7.20. 1-7.20. 41, 2013
Human mutation rate associated with DNA replication timing
JA Stamatoyannopoulos, I Adzhubei, RE Thurman, GV Kryukov, ...
Nature genetics 41 (4), 393-395, 2009
A universal trend of amino acid gain and loss in protein evolution
IK Jordan, FA Kondrashov, IA Adzhubei, YI Wolf, EV Koonin, ...
Nature 433 (7026), 633-638, 2005
No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans
R Do, D Balick, H Li, I Adzhubei, S Sunyaev, D Reich
Nature genetics 47 (2), 126-131, 2015
Mutation mapping and identification by whole-genome sequencing
I Leshchiner, K Alexa, P Kelsey, I Adzhubei, CA Austin-Tse, JD Cooney, ...
Genome research 22 (8), 1541-1548, 2012
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge
CA Brownstein, AH Beggs, N Homer, B Merriman, TW Yu, KC Flannery, ...
Genome biology 15 (3), 1-18, 2014
Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis
D Diogo, F Kurreeman, EA Stahl, KP Liao, N Gupta, JD Greenberg, ...
The American Journal of Human Genetics 92 (1), 15-27, 2013
Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions
BA Thompson, MS Greenblatt, MP Vallee, JC Herkert, C Tessereau, ...
Human mutation 34 (1), 255-265, 2013
Protein identification pipeline for the homology-driven proteomics
M Junqueira, V Spirin, TS Balbuena, H Thomas, I Adzhubei, S Sunyaev, ...
Journal of proteomics 71 (3), 346-356, 2008
Nonuniform size distribution of nascent globin peptides, evidence for pause localization sites, and a cotranslational protein-folding model
IA Krasheninnikov, AA Komar, IA Adzhubei
Journal of protein chemistry 10 (5), 445-453, 1991
Separating the wheat from the chaff: unbiased filtering of background tandem mass spectra improves protein identification
M Junqueira, V Spirin, T Santana Balbuena, P Waridel, V Surendranath, ...
Journal of proteome research 7 (8), 3382-3395, 2008
Hypermutable non-synonymous sites are under stronger negative selection
S Schmidt, A Gerasimova, FA Kondrashov, IA Adzuhbei, AS Kondrashov, ...
PLoS genetics 4 (11), e1000281, 2008
An Integrated Sequence-Structure Database incorporating matching mRNA sequence, amino acid sequence and protein three-dimensional structure data
IA Adzhubei, AA Adzhubei, S Neidle
Nucleic acids research 26 (1), 327-331, 1998
ISSD Version 2.0: taxonomic range extended
IA Adzhubei, AA Adzhubei
Nucleic acids research 27 (1), 268-271, 1999
Natural polypeptides in left‐handed helical conformation A circular dichroism study of the linker histones’ C‐terminal fragments and β‐endorphin
AA Makarov, VM Lobachov, IA Adzhubei, NG Esipova
FEBS letters 306 (1), 63-65, 1992
Scanning microcalorimetry and circular dichroism study of melting of the natural polypeptides in the left-handed helical conformation
AA Makarov, IA Adzhubei, II Protasevich, VM Lobachov, NG Esipova
Journal of protein chemistry 12 (1), 85-91, 1993
Melting of the left‐handed helical conformation of charged poly‐L‐lysine
AA Makarov, IA Adzhubei, II Protasevich, VM Lobachov, GD Fasman
Biopolymers: Original Research on Biomolecules 34 (8), 1123-1124, 1994
Transcriptomic insights into genetic diversity of protein-coding genes in X. laevis
V Savova, EJ Pearl, E Boke, A Nag, I Adzhubei, ME Horb, L Peshkin
Developmental biology 424 (2), 181-188, 2017
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