Initial sequencing and analysis of the human genome US DOE Joint Genome Institute: Hawkins Trevor 4 Branscomb Elbert 4 Predki ... Nature 409 (6822), 860-921, 2001 | 24463 | 2001 |
RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination H Lehrach, D Diamond, JM Wozney, H Boedtker Biochemistry 16 (21), 4743-4751, 1977 | 3894 | 1977 |
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, ... Cell 87 (3), 493-506, 1996 | 3609 | 1996 |
A human protein-protein interaction network: a resource for annotating the proteome U Stelzl, U Worm, M Lalowski, C Haenig, FH Brembeck, H Goehler, ... Cell 122 (6), 957-968, 2005 | 2911 | 2005 |
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes ME MacDonald, CM Ambrose, MP Duyao, RH Myers, C Lin, L Srinidhi, ... Cell 72 (6), 971-983, 1993 | 2261 | 1993 |
The genome sequence of Schizosaccharomyces pombe V Wood, R Gwilliam, MA Rajandream, M Lyne, R Lyne, A Stewart, ... Nature 415 (6874), 871-880, 2002 | 2127 | 2002 |
Transcriptome and genome sequencing uncovers functional variation in humans T Lappalainen, M Sammeth, MR Friedländer, PAC ‘t Hoen, J Monlong, ... Nature 501 (7468), 506-511, 2013 | 2101 | 2013 |
Lambda replacement vectors carrying polylinker sequences AM Frischauf, H Lehrach, A Poustka, N Murray Journal of molecular biology 170 (4), 827-842, 1983 | 1957 | 1983 |
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, ... Cell 90 (3), 549-558, 1997 | 1602 | 1997 |
A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome M Sultan, MH Schulz, H Richard, A Magen, A Klingenhoff, M Scherf, ... Science 321 (5891), 956-960, 2008 | 1593 | 2008 |
The DNA sequence of human chromosome 21 M Hattori, A Fujiyama, TD Taylor, H Watanabe, T Yada, HS Park, ... Nature 405 (6784), 311-319, 2000 | 1503 | 2000 |
The DNA sequence of the human X chromosome MT Ross, DV Grafham, AJ Coffey, S Scherer, K McLay, D Muzny, ... Nature 434 (7031), 325-337, 2005 | 1408 | 2005 |
Cloning of the T gene required in mesoderm formation in the mouse BG Herrmann, S Labeit, A Poustka, TR King, H Lehrach Nature 343 (6259), 617-622, 1990 | 1025 | 1990 |
The genome of a songbird WC Warren, DF Clayton, H Ellegren, AP Arnold, LDW Hillier, A Künstner, ... Nature 464 (7289), 757-762, 2010 | 976 | 2010 |
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 975 | 2012 |
Transcriptome analysis by strand-specific sequencing of complementary DNA D Parkhomchuk, T Borodina, V Amstislavskiy, M Banaru, L Hallen, ... Nucleic acids research 37 (18), e123-e123, 2009 | 916 | 2009 |
Systems biology in practice: concepts, implementation and application E Klipp, R Herwig, A Kowald, C Wierling, H Lehrach John Wiley & Sons, 2005 | 907 | 2005 |
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington’s disease pathology E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, ... Proceedings of the National Academy of Sciences 96 (8), 4604-4609, 1999 | 891 | 1999 |
A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets F Francis, S Hennig, B Korn, R Reinhardt, P De Jong, A Poustka, ... Nature genetics 11 (2), 130-136, 1995 | 874 | 1995 |
A physical map of the human genome. JD McPherson, M Marra, LD Hillier, RH Waterston, A Chinwalla, J Wallis, ... Nature 409 (6822), 2001 | 869 | 2001 |