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Johannes Zuegg
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Metal complexes as a promising source for new antibiotics
A Frei, J Zuegg, AG Elliott, M Baker, S Braese, C Brown, F Chen, ...
Chemical science 11 (10), 2627-2639, 2020
3522020
Contribution of amphipathicity and hydrophobicity to the antimicrobial activity and cytotoxicity of β-hairpin peptides
IA Edwards, AG Elliott, AM Kavanagh, J Zuegg, MAT Blaskovich, ...
ACS infectious diseases 2 (6), 442-450, 2016
2242016
Helping chemists discover new antibiotics
MAT Blaskovich, J Zuegg, AG Elliott, MA Cooper
ACS infectious diseases 1 (7), 285-287, 2015
2092015
Identification of active-site residues of the pro-metastatic endoglycosidase heparanase
MD Hulett, JR Hornby, SJ Ohms, J Zuegg, C Freeman, JE Gready, ...
Biochemistry 39 (51), 15659-15667, 2000
1972000
Imperfect coordination chemistry facilitates metal ion release in the Psa permease
RM Couñago, MP Ween, SL Begg, M Bajaj, J Zuegg, ML O'mara, ...
Nature chemical biology 10 (1), 35-41, 2014
1522014
Metals to combat antimicrobial resistance
A Frei, AD Verderosa, AG Elliott, J Zuegg, MAT Blaskovich
Nature Reviews Chemistry 7 (3), 202-224, 2023
1512023
The antimicrobial potential of cannabidiol
MAT Blaskovich, AM Kavanagh, AG Elliott, B Zhang, S Ramu, M Amado, ...
Communications biology 4 (1), 1-18, 2021
1422021
Protein-inspired antibiotics active against vancomycin-and daptomycin-resistant bacteria
MAT Blaskovich, KA Hansford, Y Gong, MS Butler, C Muldoon, JX Huang, ...
Nature communications 9 (1), 22, 2018
1252018
Molecular diversity through sugar scaffolds
GT Le, G Abbenante, B Becker, M Grathwohl, J Halliday, G Tometzki, ...
Drug Discovery Today 8 (15), 701-709, 2003
1212003
Molecular dynamics simulations of human prion protein: importance of correct treatment of electrostatic interactions
J Zuegg, JE Gready
Biochemistry 38 (42), 13862-13876, 1999
1201999
A probabilistic measure for alignment-free sequence comparison
TD Pham, J Zuegg
Bioinformatics 20 (18), 3455-3461, 2004
1172004
An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria
AG Elliott, JX Huang, S Neve, J Zuegg, IA Edwards, AK Cain, CJ Boinett, ...
Nature communications 11 (1), 3184, 2020
1132020
Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor
J Zuegg, JE Gready
Glycobiology 10 (10), 959-974, 2000
1102000
Three-dimensional structures of enzyme–substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis
J Zuegg, K Gruber, M Gugganig, UG Wagner, C Kratky
Protein Science 8 (10), 1990-2000, 1999
861999
Molecular reasons for lipase-sensitivity against acetaldehyde
HK Weber, J Zuegg, K Faber, J Pleissb
Journal of Molecular Catalysis B: Enzymatic 3 (1-4), 131-138, 1997
691997
Selectivity of lipases: Conformational analysis of suggested intermediates in ester hydrolysis of chiral primary and secondary alcohols
J Zuegg, H Hönig, JD Schrag, M Cygler
Journal of Molecular Catalysis B: Enzymatic 3 (1-4), 83-98, 1997
651997
Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening
J Zuegg, M A Cooper
Current topics in medicinal chemistry 12 (14), 1500-1513, 2012
592012
G. Dowson, C.; Dujardin, G
A Frei, J Zuegg, AG Elliott, M Baker, S Braese, C Brown, F Chen
Jung, N, 2627-2639, 2020
572020
An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants
W Phetsang, MAT Blaskovich, MS Butler, JX Huang, J Zuegg, ...
Bioorganic & medicinal chemistry 22 (16), 4490-4498, 2014
552014
Vancomycin: ligand recognition, dimerization and super‐complex formation
ZG Jia, ML O'Mara, J Zuegg, MA Cooper, AE Mark
The FEBS journal 280 (5), 1294-1307, 2013
542013
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Articles 1–20