| The TB structural genomics consortium: providing a structural foundation for drug discovery CW Goulding, M Apostol, DH Anderson, HS Gill, CV Smith, MR Kuo, ... Current Drug Targets-Infectious Disorders 2 (2), 121-141, 2002 | 101 | 2002 |
| The potential impact of structural genomics on tuberculosis drug discovery VL Arcus, JS Lott, JM Johnston, EN Baker Drug discovery today 11 (1-2), 28-34, 2006 | 64 | 2006 |
| The TB Structural Genomics Consortium: a decade of progress N Chim, JE Habel, JM Johnston, I Krieger, L Miallau, ... Tuberculosis 91 (2), 155-172, 2011 | 62 | 2011 |
| Crystal Structure of a Putative Methyltransferase from Mycobacterium tuberculosis: Misannotation of a Genome Clarified by Protein Structural Analysis JM Johnston, VL Arcus, CJ Morton, MW Parker, EN Baker Journal of bacteriology 185 (14), 4057-4065, 2003 | 47 | 2003 |
| Implications of Binding Mode and Active Site Flexibility for Inhibitor Potency against the Salicylate Synthase from Mycobacterium tuberculosis G Chi, A Manos-Turvey, PD O’Connor, JM Johnston, GL Evans, EN Baker, ... Biochemistry 51 (24), 4868-4879, 2012 | 45 | 2012 |
| Advances in menaquinone biosynthesis: sublocalisation and allosteric regulation JM Johnston, EMM Bulloch Current opinion in structural biology 65, 33-41, 2020 | 31 | 2020 |
| Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms JM Johnston, VL Arcus, EN Baker Acta Crystallographica Section D: Biological Crystallography 61 (9), 1199-1206, 2005 | 30 | 2005 |
| Structural views along the Mycobacterium tuberculosis MenD reaction pathway illuminate key aspects of thiamin diphosphate-dependent enzyme mechanisms ENM Jirgis, G Bashiri, EMM Bulloch, JM Johnston, EN Baker Structure 24 (7), 1167-1177, 2016 | 29 | 2016 |
| Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex G Bashiri, JM Johnston, GL Evans, EMM Bulloch, DC Goldstone, ... Acta Crystallographica Section D: Biological Crystallography 71 (11), 2297-2308, 2015 | 23 | 2015 |
| Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis G Bashiri, LV Nigon, ENM Jirgis, NAT Ho, T Stanborough, SS Dawes, ... Journal of Biological Chemistry 295 (12), 3759-3770, 2020 | 19 | 2020 |
| Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein J Jung, G Bashiri, JM Johnston, AS Brown, DF Ackerley, EN Baker Journal of structural biology 188 (3), 274-278, 2014 | 17 | 2014 |
| Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis JM Johnston, M Jiang, Z Guo, EN Baker Acta Crystallographica Section D: Biological Crystallography 66 (8), 909-917, 2010 | 14 | 2010 |
| The structure of an ancient conserved domain establishes a structural basis for stable histidine phosphorylation and identifies a new family of adenosine-specific kinases JS Lott, B Paget, JM Johnston, LTJ Delbaere, JA Sigrell-Simon, ... Journal of biological chemistry 281 (31), 22131-22141, 2006 | 10 | 2006 |
| Crystal structures of E. coli native MenH and two active site mutants JM Johnston, M Jiang, Z Guo, EN Baker PloS one 8 (4), e61325, 2013 | 9 | 2013 |
| Exploiting structural modelling tools to explore host-translocated effector proteins S Amoozadeh, J Johnston, CN Meisrimler International Journal of Molecular Sciences 22 (23), 12962, 2021 | 7 | 2021 |
| Structure of a double CACHE chemoreceptor ligand-binding domain from Pseudomonas syringae provides insights into the basis of proline recognition MKG Ehrhardt, ML Gerth, JM Johnston Biochemical and Biophysical Research Communications 549, 194-199, 2021 | 7 | 2021 |
| Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis J Jung, G Bashiri, JM Johnston, EN Baker FEBS Open Bio 6 (12), 1220-1226, 2016 | 7 | 2016 |
| A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket AF Chai, EMM Bulloch, GL Evans, JS Lott, EN Baker, JM Johnston Acta Crystallographica Section D: Biological Crystallography 71 (4), 862-872, 2015 | 7 | 2015 |
| Allosteric inhibition of Staphylococcus aureus MenD by 1,4-dihydroxy naphthoic acid: a feedback inhibition mechanism of the menaquinone biosynthesis pathway T Stanborough, NAT Ho, EMM Bulloch, G Bashiri, SS Dawes, ... Philosophical Transactions of the Royal Society B 378 (1871), 20220035, 2023 | 4 | 2023 |
| Crystal structure of a bicupin protein HutD involved in histidine utilization in Pseudomonas ML Gerth, Y Liu, W Jiao, XX Zhang, EN Baker, JS Lott, PB Rainey, ... Proteins: Structure, Function, and Bioinformatics 85 (8), 1580-1588, 2017 | 3 | 2017 |
Edward N. BakerDistinguished Professor of Structural Biology, School of Biological Sciences, University of AucklandVerified email at auckland.ac.nz
