Colin Semple

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Martin S. TaylorProfessor, MRC Human Genetics Unit, Institute of Genetics and Cancer, University of EdinburghVerified email at ed.ac.uk
Carninci PieroRIKEN IMS (Yokohama, JP) and Human Technopole (Milan, IT)Verified email at postman.riken.jp
Alison MeynertFulcrum GenomicsVerified email at fulcrumgenomics.com
James PrendergastUniversity of EdinburghVerified email at roslin.ed.ac.uk
Hideya KawajiTokyo Metropolitan Institute of Medical ScienceVerified email at igakuken.or.jp
Chris HaleyUniversity of EdinburghVerified email at igmm.ed.ac.uk
Vera B KaiserMRC Human Genetics UnitVerified email at igmm.ed.ac.uk
Carsten O. DaubAssociate Professor, Karolinska InstitutetVerified email at ki.se
Alistair ForrestSystems Biology and Genomics Lab, Harry Perkins Institute of Medical Research, UWAVerified email at perkins.uwa.edu.au
Nuria Lopez-BigasICREA Research Professor at the Institute for Research in BiomedicineVerified email at irbbarcelona.org
Benjamin L. MooreIlluminaVerified email at illumina.com
Stephanie Le Hellarduniversity of bergenVerified email at med.uib.no
Attila GyeneseiSzentágothai Research Centre, University of PécsVerified email at pte.hu
W BickmoreMRC Human Genetics Unit, University of EdinburghVerified email at igmm.ed.ac.uk
Gracjan MichlewskiProfessor, Head of Dioscuri Centre for RNA-Protein Interactions in Human Health and DiseaseVerified email at iimcb.gov.pl
Javier F. CaceresMRC Human Genetics UnitVerified email at ed.ac.uk
Yael CostaWellcome Trust-MRC Cambridge Stem Cell InstituteVerified email at cam.ac.uk
David HumeMater Research Institute-University of QueenslandVerified email at uq.edu.au
Nick GoldmanEMBL-European Bioinformatics InstituteVerified email at ebi.ac.uk
Emily V ChambersUniversity of SheffieldVerified email at sheffield.ac.uk

Colin Semple

Professor/Head of Bioinformatics, MRC Human Genetics Unit, University of Edinburgh

Verified email at ed.ac.uk - Homepage

Bioinformatics genomics evolution


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The transcriptional landscape of the mammalian genome P Carninci, T Kasukawa, S Katayama, J Gough, MC Frith, N Maeda, ... science 309 (5740), 1559-1563, 2005	4138	2005
An atlas of active enhancers across human cell types and tissues R Andersson, C Gebhard, I Miguel-Escalada, I Hoof, J Bornholdt, M Boyd, ... Nature 507 (7493), 455-461, 2014	2759	2014
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs RIKEN Genome Exploration Research Group Phase I Team: Carninci P. 2 Hayatsu ... Nature 420 (6915), 563-573, 2002	2159	2002
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020	1968*	2020
A promoter-level mammalian expression atlas Nature 507 (7493), 462-470, 2014	1780	2014
Genome-wide analysis of mammalian promoter architecture and evolution P Carninci, A Sandelin, B Lenhard, S Katayama, K Shimokawa, ... Nature genetics 38 (6), 626-635, 2006	1654	2006
Disruption of two novel genes by a translocation co-segregating with schizophrenia JK Millar, JC Wilson-Annan, S Anderson, S Christie, MS Taylor, ... Human molecular genetics 9 (9), 1415-1423, 2000	1600	2000
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection YJ Crow, A Leitch, BE Hayward, A Garner, R Parmar, E Griffith, M Ali, ... Nature genetics 38 (8), 910-916, 2006	794	2006
A high-resolution anatomical atlas of the transcriptome in the mouse embryo G Diez-Roux, S Banfi, M Sultan, L Geffers, S Anand, D Rozado, A Magen, ... PLoS biology 9 (1), e1000582, 2011	691	2011
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 A Tenesa, SM Farrington, JGD Prendergast, ME Porteous, M Walker, ... Nature genetics 40 (5), 631-637, 2008	691	2008
Proteins containing the UBA domain are able to bind to multi-ubiquitin chains CRM Wilkinson, M Seeger, R Hartmann-Petersen, M Stone, M Wallace, ... Nature cell biology 3 (10), 939-943, 2001	543	2001
Posttranscriptional regulation of miRNAs harboring conserved terminal loops G Michlewski, S Guil, CA Semple, JF Cáceres Molecular cell 32 (3), 383-393, 2008	436	2008
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line Nature genetics 41 (5), 553-562, 2009	422	2009
Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation J Fraser, C Ferrai, AM Chiariello, M Schueler, T Rito, G Laudanno, ... Molecular systems biology 11 (12), 852, 2015	394	2015
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages K Schroder, KM Irvine, MS Taylor, NJ Bokil, KA Le Cao, KA Masterman, ... Proceedings of the National Academy of Sciences 109 (16), E944-E953, 2012	350	2012
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk MG Dunlop, SE Dobbins, SM Farrington, AM Jones, C Palles, N Whiffin, ... Nature genetics 44 (7), 770-776, 2012	288	2012
POCUS: mining genomic sequence annotation to predict disease genes FS Turner, DR Clutterbuck, CAM Semple Genome biology 4, 1-9, 2003	273	2003
Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the centre of meiosis Y Costa, R Speed, R Öllinger, M Alsheimer, CA Semple, P Gautier, ... Journal of cell science 118 (12), 2755-2762, 2005	254	2005
Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells N Reynolds, B Collier, K Maratou, V Bingham, RM Speed, M Taggart, ... Human molecular genetics 14 (24), 3899-3909, 2005	228	2005
Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway ER Nimmo, JG Prendergast, MC Aldhous, NA Kennedy, P Henderson, ... Inflammatory bowel diseases 18 (5), 889-899, 2012	212	2012

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