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Martins Otikovs
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Carbonic Anhydrase Generates CO2 and H+ That Drive Spider Silk Formation Via Opposite Effects on the Terminal Domains
M Andersson, G Chen, M Otikovs, M Landreh, K Nordling, N Kronqvist, ...
PLoS biology 12 (8), e1001921, 2014
1992014
Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation
N Kronqvist, M Otikovs, V Chmyrov, G Chen, M Andersson, K Nordling, ...
Nature communications 5 (1), 3254, 2014
1672014
Efficient protein production inspired by how spiders make silk
N Kronqvist, M Sarr, A Lindqvist, K Nordling, M Otikovs, L Venturi, ...
Nature communications 8 (1), 15504, 2017
1172017
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV
D Rasina, M Otikovs, J Leitans, R Recacha, OV Borysov, I Kanepe-Lapsa, ...
Journal of Medicinal Chemistry 59 (1), 374-387, 2016
592016
Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit
K Jaudzems, K Tars, G Maurops, N Ivdra, M Otikovs, J Leitans, ...
ACS medicinal chemistry letters 5 (4), 373-377, 2014
512014
Diversified structural basis of a conserved molecular mechanism for pH‐dependent dimerization in spider silk N‐terminal domains
M Otikovs, G Chen, K Nordling, M Landreh, Q Meng, H Jörnvall, ...
Chembiochem 16 (12), 1720-1724, 2015
432015
Degree of biomimicry of artificial spider silk spinning assessed by NMR spectroscopy
M Otikovs, M Andersson, Q Jia, K Nordling, Q Meng, LB Andreas, ...
Angewandte Chemie 129 (41), 12745-12749, 2017
292017
Structural characterization of CspZ, a complement regulator factor H and FHL‐1 binding protein from Borrelia burgdorferi
K Brangulis, I Petrovskis, A Kazaks, J Bogans, M Otikovs, K Jaudzems, ...
The FEBS journal 281 (11), 2613-2622, 2014
222014
A regularized reconstruction pipeline for high‐definition diffusion MRI in challenging regions incorporating a per‐shot image correction
SF Cousin, G Liberman, E Solomon, M Otikovs, L Frydman
Magnetic resonance in medicine 82 (4), 1322-1330, 2019
182019
Diffusivity in breast malignancies analyzed for b > 1000 s/mm2 at 1 mm in‐plane resolutions: Insight from Gaussian and non‐Gaussian behaviors
M Otikovs, N Nissan, E Furman‐Haran, D Anaby, TM Allweis, R Agassi, ...
Journal of Magnetic Resonance Imaging 53 (6), 1913-1925, 2021
152021
Natural Abundance, Single-Scan 13C–13C-Based Structural Elucidations by Dissolution DNP NMR
M Otikovs, GL Olsen, E Kupče, L Frydman
Journal of the American Chemical Society 141 (5), 1857-1861, 2019
152019
Simultaneous multi-banding and multi-echo phase encoding for the accelerated acquisition of high-resolution volumetric diffusivity maps by spatiotemporally encoded MRI
L Ma, M Otikovs, SF Cousin, G Liberman, Q Bao, L Frydman
Magnetic Resonance Imaging 79, 130-139, 2021
52021
Unsupervised cycle‐consistent network using restricted subspace field map for removing susceptibility artifacts in EPI
Q Bao, W Xie, M Otikovs, L Xia, H Xie, X Liu, K Liu, Z Zhang, F Chen, ...
Magnetic Resonance in Medicine 90 (2), 458-472, 2023
32023
Mutually communicated model based on multi‐parametric MRI for automated segmentation and classification of prostate cancer
K Liu, P Li, M Otikovs, X Ning, L Xia, X Wang, L Yang, F Pan, Z Zhang, ...
Medical Physics 50 (6), 3445-3458, 2023
22023
Solution Structure of Tubuliform Spidroin N-Terminal Domain and Implications for pH Dependent Dimerization
M Šede, J Fridmanis, M Otikovs, J Johansson, A Rising, N Kronqvist, ...
Frontiers in Molecular Biosciences 9, 936887, 2022
22022
Solution NMR structure of Borrelia burgdorferi outer surface lipoprotein BBP28, a member of the mlp protein family
J Fridmanis, M Otikovs, K Brangulis, K Tārs, K Jaudzems
Proteins: Structure, Function, and Bioinformatics, 2020
22020
Novel Substituted 2-Aminoquinazolin-4 (3H)-One Derivatives as Malarial Aspartic Protease Inhibitors
A Jirgensons, I Domraceva, I Lapsa, D Rasina, K Jaudzems, M Otikovs
WO Patent WO2,015,063,544, 2015
22015
Spatiotemporal encoding MRI using subspace-constrained sampling and locally-low-rank regularization: Applications to diffusion weighted and diffusion kurtosis imaging of human …
M Otikovs, A Basak, L Frydman
Magnetic Resonance Imaging 94, 151-160, 2022
12022
Unsupervised deep learning model for correcting Nyquist ghosts of single‐shot spatiotemporal encoding
Q Bao, X Liu, J Xu, L Xia, M Otikovs, H Xie, K Liu, Z Zhang, X Zhou, C Liu
Magnetic Resonance in Medicine 91 (4), 1368-1383, 2024
2024
Relaxation–Diffusion T2–ADC Correlations in Breast Cancer Patients: A Spatiotemporally Encoded 3T MRI Assessment
M Otikovs, N Nissan, E Furman-Haran, D Anaby, R Agassi, M Sklair-Levy, ...
Diagnostics 13 (23), 3516, 2023
2023
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