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Ahmed H.E. Hassan
Ahmed H.E. Hassan
Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University
Verified email at mans.edu.eg - Homepage
Title
Cited by
Cited by
Year
Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors
A El-Demerdash, AA Al-Karmalawy, TM Abdel-Aziz, SS Elhady, ...
RSC advances 11 (50), 31339-31363, 2021
582021
Natural products hybrids: 3, 5, 4′-Trimethoxystilbene-5, 6, 7-trimethoxyflavone chimeric analogs as potential cytotoxic agents against diverse human cancer cells
AHE Hassan, E Choi, YM Yoon, KW Lee, SY Yoo, MC Cho, JS Yang, ...
European Journal of Medicinal Chemistry 161, 559-580, 2019
472019
Nanomedicine as a putative approach for active targeting of hepatocellular carcinoma
MH Elnaggar, AI Abushouk, AHE Hassan, HM Lamloum, A Benmelouka, ...
Seminars in cancer biology 69, 91-99, 2021
422021
Repurposing mosloflavone/5, 6, 7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of …
AHE Hassan, SY Yoo, KW Lee, YM Yoon, HW Ryu, Y Jeong, JS Shin, ...
European journal of medicinal chemistry 180, 253-267, 2019
422019
EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl) phenoxy) pyrimidin-5-yl) benzamide as a novel anti-inflammatory EGFR inhibitor
A Elkamhawy, AHE Hassan, S Paik, YS Lee, HH Lee, JS Shin, KT Lee, ...
Bioorganic Chemistry 86, 112-118, 2019
382019
Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4 + 3] Cycloaddition/SmI2-Pinacol Coupling
AHE Hassan, JK Lee, AN Pae, SJ Min, YS Cho
Organic letters 17 (11), 2672-2675, 2015
382015
Flavone-based arylamides as potential anticancers: design, synthesis and in vitro cell-based/cell-free evaluations
AHE Hassan, KT Lee, YS Lee
European journal of medicinal chemistry 187, 111965, 2020
332020
Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents
S Kang, JM Lee, B Jeon, A Elkamhawy, S Paik, J Hong, SJ Oh, SH Paek, ...
European Journal of Medicinal Chemistry 151, 186-198, 2018
332018
Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2, 5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds
AK Farag, AHE Hassan, BS Ahn, KD Park, EJ Roh
Journal of enzyme inhibition and medicinal chemistry 35 (1), 311-324, 2020
302020
Design, synthesis and evaluation of alkylphosphocholine-gefitinib conjugates as multitarget anticancer agents
MM Alam, AHE Hassan, YH Kwon, HJ Lee, NY Kim, KH Min, SY Lee, ...
Archives of pharmacal research 41, 35-45, 2018
302018
First-in-class DAPK1/CSF1R dual inhibitors: Discovery of 3, 5-dimethoxy-N-(4-(4-methoxyphenoxy)-2-((6-morpholinopyridin-3-yl) amino) pyrimidin-5-yl) benzamide as a potential …
AK Farag, AHE Hassan, H Jeong, Y Kwon, JG Choi, MS Oh, KD Park, ...
European Journal of Medicinal Chemistry 162, 161-175, 2019
292019
Synthesis and evaluation of 2-(3-arylureido) pyridines and 2-(3-arylureido) pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease
A Elkamhawy, J Park, AHE Hassan, AN Pae, J Lee, BG Park, EJ Roh
European Journal of Medicinal Chemistry 144, 529-543, 2018
292018
Thiazolidine-2, 4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents
A Elkamhawy, N youn Kim, AHE Hassan, J Park, S Paik, JE Yang, KS Oh, ...
European Journal of Medicinal Chemistry 188, 111955, 2020
282020
Construction of 8-Azabicyclo[3.2.1]octanes via Sequential DDQ-Mediated Oxidative Mannich Reactions of N-Aryl Pyrrolidines
H Jo, AHE Hassan, SY Jung, JK Lee, YS Cho, SJ Min
Organic letters 20 (4), 1175-1178, 2018
282018
Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl) phenoxy) pyrimidin-5-yl) benzamide: A novel EGFR inhibitor from a designed small library
A Elkamhawy, S Paik, AHE Hassan, YS Lee, EJ Roh
Bioorganic Chemistry 75, 393-405, 2017
262017
Design, synthesis and cytotoxicity of chimeric erlotinib-alkylphospholipid hybrids
MM Alam, AHE Hassan, KW Lee, MC Cho, JS Yang, J Song, KH Min, ...
Bioorganic Chemistry 84, 51-62, 2019
252019
Discovery of 1-(3-(benzyloxy) pyridin-2-yl)-3-(2-(piperazin-1-yl) ethyl) urea: A new modulator for amyloid beta-induced mitochondrial dysfunction
A Elkamhawy, J Park, AHE Hassan, H Ra, AN Pae, J Lee, BG Park, ...
European journal of medicinal chemistry 128, 56-69, 2017
252017
Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1, 4-dihydroisoquinolin-3 (2H)-ones: A novel class of TSPO ligands modulating amyloid-β …
A Elkamhawy, J Park, AHE Hassan, AN Pae, J Lee, BG Park, S Paik, J Do, ...
European journal of pharmaceutical sciences 104, 366-381, 2017
242017
Antiproliferative 3-deoxysphingomyelin analogs: Design, synthesis, biological evaluation and molecular docking of pyrrolidine-based 3-deoxysphingomyelin analogs as anticancer …
AHE Hassan, HR Park, YM Yoon, HI Kim, SY Yoo, KW Lee, YS Lee
Bioorganic Chemistry 84, 444-455, 2018
232018
Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-β modulators
A Elkamhawy, N youn Kim, AHE Hassan, J Park, JE Yang, KS Oh, BH Lee, ...
European Journal of Medicinal Chemistry 157, 691-704, 2018
232018
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