| Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism PB Yu, CC Hong, C Sachidanandan, JL Babitt, DY Deng, SA Hoyng, ... Nature chemical biology 4 (1), 33-41, 2008 | 1272 | 2008 |
| BMP type I receptor inhibition reduces heterotopic ossification PB Yu, DY Deng, CS Lai, CC Hong, GD Cuny, ML Bouxsein, DW Hong, ... Nature medicine 14 (12), 1363-1369, 2008 | 722 | 2008 |
| Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension L Long, ML Ormiston, X Yang, M Southwood, S Gräf, RD Machado, ... Nature medicine 21 (7), 777-785, 2015 | 474 | 2015 |
| Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors GD Cuny, BY Paul, JK Laha, X Xing, JF Liu, CS Lai, DY Deng, ... Bioorganic & medicinal chemistry letters 18 (15), 4388-4392, 2008 | 410 | 2008 |
| ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A SJ Hatsell, V Idone, DMA Wolken, L Huang, HJ Kim, L Wang, X Wen, ... Science translational medicine 7 (303), 303ra137-303ra137, 2015 | 401 | 2015 |
| Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells J Hao, MA Daleo, CK Murphy, PB Yu, JN Ho, J Hu, RT Peterson, ... PloS one 3 (8), e2904, 2008 | 282 | 2008 |
| Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis M Derwall, R Malhotra, CS Lai, Y Beppu, E Aikawa, JS Seehra, WM Zapol, ... Arteriosclerosis, thrombosis, and vascular biology 32 (3), 613-622, 2012 | 268 | 2012 |
| Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells BY Paul, H Beppu, N Kawai, E Li, KD Bloch Journal of Biological Chemistry 280 (26), 24443-24450, 2005 | 259 | 2005 |
| BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia H Beppu, F Ichinose, N Kawai, RC Jones, PB Yu, WM Zapol, K Miyazono, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 287 (6 …, 2004 | 255 | 2004 |
| Targeting BMP signalling in cardiovascular disease and anaemia NW Morrell, DB Bloch, P Ten Dijke, MJTH Goumans, A Hata, J Smith, ... Nature Reviews Cardiology 13 (2), 106-120, 2016 | 236 | 2016 |
| A new class of small molecule inhibitor of BMP signaling CE Sanvitale, G Kerr, A Chaikuad, MC Ramel, AH Mohedas, S Reichert, ... PloS one 8 (4), e62721, 2013 | 235 | 2013 |
| Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts N Kamiya, T Kobayashi, Y Mochida, PB Yu, M Yamauchi, HM Kronenberg, ... Journal of Bone and Mineral Research 25 (2), 200-210, 2010 | 232 | 2010 |
| Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice AU Steinbicker, TB Bartnikas, LK Lohmeyer, P Leyton, C Mayeur, SM Kao, ... Blood, The Journal of the American Society of Hematology 118 (15), 4224-4230, 2011 | 207 | 2011 |
| Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva T Fukuda, M Kohda, K Kanomata, J Nojima, A Nakamura, J Kamizono, ... Journal of Biological Chemistry 284 (11), 7149-7156, 2009 | 206 | 2009 |
| Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation AU Steinbicker, C Sachidanandan, AJ Vonner, RZ Yusuf, DY Deng, ... Blood, The Journal of the American Society of Hematology 117 (18), 4915-4923, 2011 | 204 | 2011 |
| Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells JH Boergermann, J Kopf, PB Yu, P Knaus The international journal of biochemistry & cell biology 42 (11), 1802-1807, 2010 | 197 | 2010 |
| Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification D Dey, J Bagarova, SJ Hatsell, KA Armstrong, L Huang, J Ermann, ... Science translational medicine 8 (366), 366ra163-366ra163, 2016 | 180 | 2016 |
| Transforming growth factor β can stimulate Smad1 phosphorylation independently of bone morphogenic protein receptors KH Wrighton, X Lin, BY Paul, XH Feng Journal of Biological Chemistry 284 (15), 9755-9763, 2009 | 164 | 2009 |
| Development of an ALK2-biased BMP type I receptor kinase inhibitor AH Mohedas, X Xing, KA Armstrong, AN Bullock, GD Cuny, PB Yu ACS chemical biology 8 (6), 1291-1302, 2013 | 159 | 2013 |
| Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4 Y Xia, BY Paul, Y Sidis, H Beppu, KD Bloch, AL Schneyer, HY Lin Journal of biological chemistry 282 (25), 18129-18140, 2007 | 139 | 2007 |
Randall PetersonUniversity of Utahبريد إلكتروني تم التحقق منه على pharm.utah.edu
