| Design, synthesis and molecular modeling studies of new series of s-triazine derivatives as antimicrobial agents against multi-drug resistant clinical isolates NS Haiba, HH Khalil, MA Moniem, MH El-Wakil, AA Bekhit, SN Khattab Bioorganic Chemistry 89, 103013, 2019 | 31 | 2019 |
| New chalcone-tethered 1, 3, 5-triazines potentiate the anticancer effect of cisplatin against human lung adenocarcinoma A549 cells by enhancing DNA damage and cell apoptosis MH El-Wakil, SN Khattab, AF El-Yazbi, N El-Nikhely, A Soffar, HH Khalil Bioorganic Chemistry 105, 104393, 2020 | 30 | 2020 |
| Discovery of a novel DNA binding agent via design and synthesis of new thiazole hybrids and fused 1, 2, 4-triazines as potential antitumor agents: Computational, spectrometric … MH El-Wakil, AF El-Yazbi, HMA Ashour, MA Khalil, KA Ismail, IM Labouta Bioorganic chemistry 90, 103089, 2019 | 27 | 2019 |
| Synthesis of some (E)-6-[2-(furan-2-yl)ethenyl]-1,2,4-triazin-5-ones and their biological evaluation as antitumor agents HM Ashour, MH El-Wakil, MA Khalil, KA Ismail, IM Labouta Medicinal Chemistry Research 22, 1909-1924, 2013 | 27 | 2013 |
| Design, synthesis and molecular modeling studies of new series of antitumor 1, 2, 4-triazines with potential c-Met kinase inhibitory activity MH El-Wakil, HM Ashour, MN Saudi, AM Hassan, IM Labouta Bioorganic Chemistry 76, 154-165, 2018 | 25 | 2018 |
| Target identification, lead optimization and antitumor evaluation of some new 1, 2, 4-triazines as c-Met kinase inhibitors MH El-Wakil, HM Ashour, MN Saudi, AM Hassan, IM Labouta Bioorganic chemistry 73, 154-169, 2017 | 24 | 2017 |
| Structural optimization, synthesis and in vitro synergistic anticancer activities of combinations of new N3-substituted dihydropyrimidine calcium channel blockers with … MH El-Wakil, M Teleb, MM Abu-Serie, S Huang, GW Zamponi, H Fahmy Bioorganic Chemistry 115, 105262, 2021 | 10 | 2021 |
| Transforming Type II to Type I c-Met kinase inhibitors via combined scaffold hopping and structure-guided synthesis of new series of 1, 3, 4-thiadiazolo [2, 3-c]-1, 2, 4 … MH El-Wakil, M Teleb Bioorganic Chemistry 116, 105304, 2021 | 8 | 2021 |
| Nitrofurazone repurposing towards design and synthesis of novel apoptotic-dependent anticancer and antimicrobial agents: Biological evaluation, kinetic studies and molecular … MH El-Wakil, MA Meheissen, MM Abu-Serie Bioorganic Chemistry 113, 104971, 2021 | 8 | 2021 |
| Identification of a Novel DNA Gyrase Inhibitor via Design and Synthesis of New Antibacterial Pyrido[1′,2′:1,2]pyrimido[4,5‐e][1,3,4]thiadiazin‐5‐ol Derivatives HH Khalil, SN Khattab, MM Toughan, AMM El‐Saghier, MH El‐Wakil ChemistrySelect 5 (22), 6556-6564, 2020 | 2 | 2020 |
| Identification of new 5-(2, 6-dichlorophenyl)-3-oxo-2, 3-dihydro-5H-thiazolo [3, 2-a] pyrimidine-7-carboxylic acids as p38α MAPK inhibitors: Design, synthesis, antitumor … MH El-Wakil, HA El-Dershaby, RA Ghazallah, AF El-Yazbi, ... Bioorganic Chemistry, 107226, 2024 | | 2024 |
| BMS-777607 MH El-Wakil, HM Ashour, MN Saudi, AM Hassan, IM Labouta | | |
