Mireia Castillo-Martin
Mireia Castillo-Martin
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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
T Palomero, ML Sulis, M Cortina, PJ Real, K Barnes, M Ciofani, ...
Nature medicine 13 (10), 1203-1210, 2007
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model
CW Kinkade, M Castillo-Martin, A Puzio-Kuter, J Yan, TH Foster, H Gao, ...
The Journal of clinical investigation 118 (9), 3051-3064, 2008
γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
PJ Real, V Tosello, T Palomero, M Castillo, E Hernando, E De Stanchina, ...
Nature medicine 15 (1), 50-58, 2009
Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch-and hedgehog-dependent tumor-initiating cells
J Domingo-Domenech, SJ Vidal, V Rodriguez-Bravo, M Castillo-Martin, ...
Cancer cell 22 (3), 373-388, 2012
A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia
D Herranz, A Ambesi-Impiombato, T Palomero, SA Schnell, L Belver, ...
Nature medicine 20 (10), 1130-1137, 2014
Inactivation of p53 and Pten promotes invasive bladder cancer
AM Puzio-Kuter, M Castillo-Martin, CW Kinkade, X Wang, TH Shen, ...
Genes & development 23 (6), 675-680, 2009
Molecular pathways of urothelial development and bladder tumorigenesis
M Castillo-Martin, J Domingo-Domenech, O Karni-Schmidt, T Matos, ...
Urologic oncology: seminars and original investigations 28 (4), 401-408, 2010
PHF6 mutations in T-cell acute lymphoblastic leukemia
P Van Vlierberghe, T Palomero, H Khiabanian, J Van der Meulen, ...
Nature genetics 42 (4), 338-342, 2010
Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy
A Aytes, A Mitrofanova, C Lefebvre, MJ Alvarez, M Castillo-Martin, ...
Cancer cell 25 (5), 638-651, 2014
Massive parallel sequencing uncovers actionable FGFR2PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma
D Sia, B Losic, A Moeini, L Cabellos, K Hao, K Revill, D Bonal, ...
Nature communications 6 (1), 6087, 2015
Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia
E Piovan, J Yu, V Tosello, D Herranz, A Ambesi-Impiombato, AC Da Silva, ...
Cancer cell 24 (6), 766-776, 2013
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer
M Chen, J Zhang, K Sampieri, JG Clohessy, L Mendez, ...
Nature genetics 50 (2), 206-218, 2018
A systems biology approach identifies FUT8 as a driver of melanoma metastasis
P Agrawal, B Fontanals-Cirera, E Sokolova, S Jacob, CA Vaiana, ...
Cancer cell 31 (6), 804-819. e7, 2017
EMT-and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
L Wang, A Saci, PM Szabo, SD Chasalow, M Castillo-Martin, ...
Nature communications 9 (1), 3503, 2018
PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth
S Kuchay, C Giorgi, D Simoneschi, J Pagan, S Missiroli, A Saraf, ...
Nature 546 (7659), 554-558, 2017
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia
D Herranz, A Ambesi-Impiombato, J Sudderth, M Sánchez-Martín, ...
Nature medicine 21 (10), 1182-1189, 2015
The metabolic co-regulator PGC1α suppresses prostate cancer metastasis
V Torrano, L Valcarcel-Jimenez, AR Cortazar, X Liu, J Urosevic, ...
Nature cell biology 18 (6), 645-656, 2016
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression
M Chen, CP Pratt, ME Zeeman, N Schultz, BS Taylor, A O'Neill, ...
Cancer cell 20 (2), 173-186, 2011
The TLX1 oncogene drives aneuploidy in T cell transformation
K De Keersmaecker, PJ Real, GD Gatta, T Palomero, ML Sulis, V Tosello, ...
Nature medicine 16 (11), 1321-1327, 2010
Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression
O Karni-Schmidt, M Castillo-Martin, T HuaiShen, N Gladoun, ...
The American journal of pathology 178 (3), 1350-1360, 2011
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