Katherine B Chiappinelli
Katherine B Chiappinelli
Assistant Professor, The George Washington University
Verified email at - Homepage
Cited by
Cited by
Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses
KB Chiappinelli, PL Strissel, A Desrichard, H Li, C Henke, B Akman, ...
Cell 162 (5), 974-986, 2015
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast Jr, V Beral, ...
Nature reviews Cancer 15 (11), 668-679, 2015
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers
H Li, KB Chiappinelli, AA Guzzetta, H Easwaran, RWC Yen, R Vatapalli, ...
Oncotarget 5 (3), 587, 2014
Epigenetic therapy ties MYC depletion to reversing immune evasion and treating lung cancer
MJ Topper, M Vaz, KB Chiappinelli, CEDS Shields, N Niknafs, RWC Yen, ...
Cell 171 (6), 1284-1300. e21, 2017
Combining epigenetic and immunotherapy to combat cancer
KB Chiappinelli, CA Zahnow, N Ahuja, SB Baylin
Cancer research 76 (7), 1683-1689, 2016
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden
ML Stone, KB Chiappinelli, H Li, LM Murphy, ME Travers, MJ Topper, ...
Proceedings of the National Academy of Sciences 114 (51), E10981-E10990, 2017
Epigenetic therapy for ovarian cancer: promise and progress
S Moufarrij, M Dandapani, E Arthofer, S Gomez, A Srivastava, ...
Clinical epigenetics 11 (1), 1-11, 2019
Novel methylation biomarker panel for the early detection of pancreatic cancer
JM Yi, AA Guzzetta, VJ Bailey, SR Downing, L Van Neste, KB Chiappinelli, ...
Clinical Cancer Research 19 (23), 6544-6555, 2013
The tumor immune microenvironment drives a prognostic relevance that correlates with bladder cancer subtypes
C Pfannstiel, PL Strissel, KB Chiappinelli, D Sikic, S Wach, RM Wirtz, ...
Cancer immunology research 7 (6), 923-938, 2019
Combining epigenetic and immune therapy to overcome cancer resistance
S Gomez, T Tabernacki, J Kobyra, P Roberts, KB Chiappinelli
Seminars in cancer biology 65, 99-113, 2020
Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells
C Siebenkäs, KB Chiappinelli, AA Guzzetta, A Sharma, J Jeschke, ...
PLoS One 12 (6), e0179501, 2017
Complete characterization of the microRNAome in a patient with acute myeloid leukemia
G Ramsingh, DC Koboldt, M Trissal, KB Chiappinelli, T Wylie, S Koul, ...
Blood, The Journal of the American Society of Hematology 116 (24), 5316-5326, 2010
FEN1 ensures telomere stability by facilitating replication fork re-initiation
A Saharia, DC Teasley, JP Duxin, B Dao, KB Chiappinelli, SA Stewart
Journal of Biological Chemistry 285 (35), 27057-27066, 2010
Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer
S Moufarrij, A Srivastava, S Gomez, M Hadley, E Palmer, PT Austin, ...
Scientific Reports 10 (1), 3470, 2020
Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers
B Zhang, XY Xing, J Li, RF Lowdon, Y Zhou, N Lin, B Zhang, V Sundaram, ...
BMC genomics 15, 1-21, 2014
Transposable element regulation and expression in cancer
EE Grundy, N Diab, KB Chiappinelli
The FEBS journal 289 (5), 1160-1179, 2022
Phosphatase and tensin homolog (PTEN) pseudogene expression in endometrial cancer: a conserved regulatory mechanism important in tumorigenesis?
YJ Ioffe, KB Chiappinelli, DG Mutch, I Zighelboim, PJ Goodfellow
Gynecologic oncology 124 (2), 340-346, 2012
Unraveling the molecular pathways of DNA-methylation inhibitors: human endogenous retroviruses induce the innate immune response in tumors
R Strick, PL Strissel, SB Baylin, KB Chiappinelli
Oncoimmunology 5 (5), e1122160, 2016
HDAC6 plays a noncanonical role in the regulation of antitumor immune responses, dissemination, and invasiveness of breast cancer
D Banik, S Noonepalle, M Hadley, E Palmer, M Gracia-Hernandez, ...
Cancer research 80 (17), 3649-3662, 2020
Locus-specific characterization of human endogenous retrovirus expression in prostate, breast, and colon cancers
MC Steiner, JL Marston, LP Iñiguez, ML Bendall, KB Chiappinelli, ...
Cancer research 81 (13), 3449-3460, 2021
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