| Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses KB Chiappinelli, PL Strissel, A Desrichard, H Li, C Henke, B Akman, ... Cell 162 (5), 974-986, 2015 | 1699 | 2015 |
| Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast Jr, V Beral, ... Nature reviews Cancer 15 (11), 668-679, 2015 | 1125 | 2015 |
| Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers H Li, KB Chiappinelli, AA Guzzetta, H Easwaran, RWC Yen, R Vatapalli, ... Oncotarget 5 (3), 587, 2014 | 438 | 2014 |
| Epigenetic therapy ties MYC depletion to reversing immune evasion and treating lung cancer MJ Topper, M Vaz, KB Chiappinelli, CEDS Shields, N Niknafs, RWC Yen, ... Cell 171 (6), 1284-1300. e21, 2017 | 408 | 2017 |
| Combining epigenetic and immunotherapy to combat cancer KB Chiappinelli, CA Zahnow, N Ahuja, SB Baylin Cancer research 76 (7), 1683-1689, 2016 | 300 | 2016 |
| Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden ML Stone, KB Chiappinelli, H Li, LM Murphy, ME Travers, MJ Topper, ... Proceedings of the National Academy of Sciences 114 (51), E10981-E10990, 2017 | 247 | 2017 |
| Epigenetic therapy for ovarian cancer: promise and progress S Moufarrij, M Dandapani, E Arthofer, S Gomez, A Srivastava, ... Clinical epigenetics 11, 1-11, 2019 | 214 | 2019 |
| Novel methylation biomarker panel for the early detection of pancreatic cancer JM Yi, AA Guzzetta, VJ Bailey, SR Downing, L Van Neste, KB Chiappinelli, ... Clinical Cancer Research 19 (23), 6544-6555, 2013 | 160 | 2013 |
| The tumor immune microenvironment drives a prognostic relevance that correlates with bladder cancer subtypes C Pfannstiel, PL Strissel, KB Chiappinelli, D Sikic, S Wach, RM Wirtz, ... Cancer immunology research 7 (6), 923-938, 2019 | 133 | 2019 |
| Combining epigenetic and immune therapy to overcome cancer resistance S Gomez, T Tabernacki, J Kobyra, P Roberts, KB Chiappinelli Seminars in cancer biology 65, 99-113, 2020 | 109 | 2020 |
| Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells C Siebenkäs, KB Chiappinelli, AA Guzzetta, A Sharma, J Jeschke, ... PLoS One 12 (6), e0179501, 2017 | 92 | 2017 |
| FEN1 ensures telomere stability by facilitating replication fork re-initiation A Saharia, DC Teasley, JP Duxin, B Dao, KB Chiappinelli, SA Stewart Journal of biological chemistry 285 (35), 27057-27066, 2010 | 83 | 2010 |
| Complete characterization of the microRNAome in a patient with acute myeloid leukemia G Ramsingh, DC Koboldt, M Trissal, KB Chiappinelli, T Wylie, S Koul, ... Blood, The Journal of the American Society of Hematology 116 (24), 5316-5326, 2010 | 81 | 2010 |
| Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer S Moufarrij, A Srivastava, S Gomez, M Hadley, E Palmer, PT Austin, ... Scientific Reports 10 (1), 3470, 2020 | 79 | 2020 |
| Transposable element regulation and expression in cancer EE Grundy, N Diab, KB Chiappinelli The FEBS journal 289 (5), 1160-1179, 2022 | 71 | 2022 |
| Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers B Zhang, XY Xing, J Li, RF Lowdon, Y Zhou, N Lin, B Zhang, V Sundaram, ... BMC genomics 15, 1-21, 2014 | 65 | 2014 |
| Phosphatase and tensin homolog (PTEN) pseudogene expression in endometrial cancer: a conserved regulatory mechanism important in tumorigenesis? YJ Ioffe, KB Chiappinelli, DG Mutch, I Zighelboim, PJ Goodfellow Gynecologic oncology 124 (2), 340-346, 2012 | 52 | 2012 |
| HDAC6 plays a noncanonical role in the regulation of antitumor immune responses, dissemination, and invasiveness of breast cancer D Banik, S Noonepalle, M Hadley, E Palmer, M Gracia-Hernandez, ... Cancer research 80 (17), 3649-3662, 2020 | 39 | 2020 |
| Unraveling the molecular pathways of DNA-methylation inhibitors: human endogenous retroviruses induce the innate immune response in tumors R Strick, PL Strissel, SB Baylin, KB Chiappinelli Oncoimmunology 5 (5), e1122160, 2016 | 37 | 2016 |
| Locus-specific characterization of human endogenous retrovirus expression in prostate, breast, and colon cancers MC Steiner, JL Marston, LP Iñiguez, ML Bendall, KB Chiappinelli, ... Cancer research 81 (13), 3449-3460, 2021 | 26 | 2021 |
