Design, synthesis and biological screening of new 4-thiazolidinone derivatives with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile KRA Abdellatif, MA Abdelgawad, HAH Elshemy, SSR Alsayed Bioorganic chemistry 64, 1-12, 2016 | 84 | 2016 |
Design and synthesis of new coumarin hybrids and insight into their mode of antiproliferative action HAH Elshemy, MA Zaki Bioorganic & Medicinal Chemistry 25 (3), 1066-1075, 2017 | 81 | 2017 |
Synthesis of novel chromene derivatives of expected antitumor activity MM Kandeel, AM Kamal, EKA Abdelall, HAH Elshemy European Journal of Medicinal Chemistry 59, 183-193, 2013 | 64 | 2013 |
New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition MA Abdelgawad, RB Bakr, W Ahmad, MM Al-Sanea, HAH Elshemy Bioorganic chemistry 92, 103218, 2019 | 56 | 2019 |
Synthesis of novel substituted 4H-chromenes and their antioxidant screening MA Abdelgawad, HAH Elshemy, KRA Abdellatif, HA Omar Journal of Chemical and Pharmaceutical Research, 2013 5 (1), 387-394, 2013 | 49* | 2013 |
Synthesis, anti-inflammatory, cyclooxygenases inhibitions assays and histopathological study of poly-substituted 1, 3, 5-triazines: Confirmation of regiospecific pyrazole … HAH Elshemy, EKA Abdelall, AA Azouz, A Moawad, WAM Ali, NM Safwat European Journal of Medicinal Chemistry 127, 10-21, 2017 | 48 | 2017 |
A multicomponent reaction to design antimalarial pyridyl-indole derivatives: Synthesis, biological activities and molecular docking HAH Elshemy, MA Zaki, EI Mohamed, SI Khan, PF Lamie Bioorganic Chemistry 97, 103673, 2020 | 40 | 2020 |
1-(4-Methane (amino) sulfonylphenyl)-3-(4-substituted-phenyl)-5-(4-trifluoromethylphenyl)-1H-2-pyrazolines/pyrazoles as potential anti-inflammatory agents KRA Abdellatif, HAH Elshemy, AA Azoz Bioorganic chemistry 63, 13-23, 2015 | 40 | 2015 |
Synthesis, characterization and biological evaluation of novel 4′-fluoro-2′-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents KRA Abdellatif, HAH Elshemy, SA Salama, HA Omar Journal of enzyme inhibition and medicinal chemistry 30 (3), 484-491, 2015 | 37 | 2015 |
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights MM Al-Sanea, A Elkamhawy, S Paik, K Lee, AM El Kerdawy, BSN Abbas, ... Bioorganic & medicinal chemistry 28 (13), 115525, 2020 | 31 | 2020 |
Design, synthesis and biological screening of some novel celecoxib and etoricoxib analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile SSR Alsayed, HAH Elshemy, MA Abdelgawad, MS Abdel-Latif, ... Bioorganic Chemistry 70, 173-183, 2017 | 30 | 2017 |
DESIGN AND SYNTHESIS OF SUBSTITUTED CHROMENES AS POTENTIAL ANTICANCER AGENTS HAHE Aliaa M. Kamal, Manal M. Kandeel, Eman K Abd El international journal of pharmaceutical research and development 4 (3), 310-322, 2012 | 29* | 2012 |
Synthesis and anti-inflammatory evaluation of new 1,3,5-triaryl-4,5-dihydro-1H-pyrazole derivatives possessing an aminosulphonyl pharmacophore KRA Abdellatif, MA Abdelgawad, HAH Elshemy, SSR Alsayed, G Kamel Archives of pharmacal research 38, 1932-1942, 2015 | 27 | 2015 |
Design, synthesis of new anti-inflammatory agents with a pyrazole core: COX-1/COX-2 inhibition assays, anti-inflammatory, ulcerogenic, histopathological, molecular Modeling … KRA Abdellatif, EKA Abdelall, HAH Elshemy, PF Lamie, E Elnahaas, ... Journal of Molecular Structure 1240, 130554, 2021 | 25 | 2021 |
Optimization of pyrazole-based compounds with 1, 2, 4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase … KRA Abdellatif, EKA Abdelall, HAH Elshemy, JN Philoppes, ... Bioorganic chemistry 114, 105122, 2021 | 24 | 2021 |
Determination of flutamide and two major metabolites using HPLC–DAD and HPTLC methods NS Abdelwahab, HAH Elshemy, NF Farid Chemistry Central Journal 12, 1-15, 2018 | 24 | 2018 |
Design, synthesis, antioxidant and anticancer activity of new coumarin derivatives linked with thiazole, isoxazole or pyrazole moiety KRA Abdellatif, MA Abdelgawad, HAH Elshemy, NM Kahk, DM El Amir Letters in Drug Design & Discovery 14 (7), 773-781, 2017 | 24 | 2017 |
Anti-inflammatory indomethacin analogs endowed with preferential COX-2 inhibitory activity NH Amin, MT El-Saadi, AA Hefny, AH Abdelazeem, HAH Elshemy, ... Future medicinal chemistry 10 (21), 2521-2535, 2018 | 18 | 2018 |
New indomethacin analogs as selective COX‐2 inhibitors: Synthesis, COX‐1/2 inhibitory activity, anti‐inflammatory, ulcerogenicity, histopathological, and docking studies KRA Abdellatif, EKA Abdelall, HAH Elshemy, ES El‐Nahass, ... Archiv der Pharmazie 354 (4), 2000328, 2021 | 16 | 2021 |
New benzoxazole derivatives as antiprotozoal agents: in silico studies, synthesis, and biological evaluation MA Abdelgawad, MM Al-Sanea, MA Zaki, EIA Mohamed, SI Khan, ... Journal of Chemistry 2021, 1-11, 2021 | 13 | 2021 |