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Ádám I. Horváth
Ádám I. Horváth
Verified email at ttk.elte.hu
Title
Cited by
Cited by
Year
Single residue variation in skeletal muscle myosin enables direct and selective drug targeting for spasticity and muscle stiffness
M Gyimesi, ÁI Horváth, D Túrós, SK Suthar, M Pénzes, C Kurdi, L Canon, ...
Cell 183 (2), 335-346. e13, 2020
292020
Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
ÁI Horváth, M Gyimesi, BH Várkuti, M Képiró, G Szegvári, I Lőrincz, ...
Scientific Reports 10 (1), 13341, 2020
92020
Investigation of the relationships between material properties and processing parameters of boron micro-alloyed quenched and tempered steels
J Loerinczi, G Kralik, M Kovacs, A Horvath
Materials Science Forum 414, 2003
92003
Titin activates myosin filaments in skeletal muscle by switching from an extensible spring to a mechanical rectifier
C Squarci, P Bianco, M Reconditi, I Pertici, M Caremani, T Narayanan, ...
Proceedings of the National Academy of Sciences 120 (9), e2219346120, 2023
72023
The New-Generation Muscle Relaxant MPH-220 Dissolves Spasticity in Muscles After Cns Injury-a Promising Drug to Address Post-Stroke Spasticity
M Gyimesi, AI Horvath, D Túrós, G Hegyi, SK Suthar, M Kovacs, ...
Biophysical Journal 118 (3), 434a, 2020
12020
Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms
A Málnási-Csizmadia, M Gyimesi, A Szabó, P Hári, SS Kumar, M Kovács, ...
US Patent 11,845,758, 2023
2023
Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms
A Málnási-Csizmadia, M Gyimesi, A Szabó, P Hári, SS Kumar, M Kovács, ...
US Patent 11,746,112, 2023
2023
Titin function in the active sarcomere studied in frog muscle fibers upon inhibition of myosin motors by para-nitro-blebbistatin
C Squarci, P Bianco, M Reconditi, I Pertici, M Caremani, T Narayanan, ...
Biophysical Journal 122 (3), 29a, 2023
2023
Regulation of APD and force by Na+/Ca2+ exchanger in hiPSC-cardiomyocytes
D Ismaili, K Gurr, A Horvath, L Yuan, MD Lemoine, C Schulz, J Sani, ...
Europace 24 (Supplement_1), euac053. 625, 2022
2022
The role of NM2 rearrangement during cytokinesis
AI Horvath, M Gyimesi, M Kepiro, B Varkuti, A Malnasi-Csizmadia
Biophysical Journal 121 (3), 259a-260a, 2022
2022
Application of neural-network-based deep-learning analysis to reveal changes of the movement parameters in rat neuromuscular disorder models
M Winternitz, M Gyimesi, AI Horvath, M Penzes, A Malnasi-Csizmadia
Biophysical Journal 121 (3), 258a-259a, 2022
2022
Passive and active mechanical properties of titin studied in intact frog muscle fibers upon inhibition of myosin motors by para-nitro-blebbistatin
C Squarci, P Bianco, M Reconditi, I Pertici, M Caremani, T Narayanan, ...
Biophysical Journal 121 (3), 515a, 2022
2022
First-in-class drug candidate (MPH-220) efficiently improves spastic gait disorders by selective inhibition of fast skeletal muscle myosin-2
M Gyimesi, AI Horvath, D Turos, SK Suthar, M Penzes, L Canon, C Kikuti, ...
Biophysical Journal 121 (3), 291a, 2022
2022
Culture conditions effect properties of the Na+/K+-ATPase pump current in hiPSC cardiomyocytes
D Ismaili, K Gurr, A Horvath, A Hansen, T Eschenhagen, T Christ
EP Europace 23 (Supplement_3), euab116. 577, 2021
2021
Abstract P221: First-In-Class Anti-Spastic Drug Candidate (MPH-220) Efficiently Relaxes Spastic Muscles and Improves Motor Functions in Gait Disorder in Preclinical Studies
M Gyimesi, A Horvath, D Turos, M Penzes, C Kurdi, M Kovacs, ...
Stroke 52 (Suppl_1), AP221-AP221, 2021
2021
First-In-Class Anti-Spastic Drug Candidate (MPH-220) Efficiently Relaxes Spastic Muscles and Improves Motor Functions in Gait Disorder in Preclinical Studies.
M Gyimesi, A Horvath, D Turos, M Penzes, C Kurdi, M Kovacs, ...
STROKE 52, 2021
2021
NEW-GENERATION ANTI-SPASTIC DRUG CANDIDATE (MPH-220) IMPROVES MOTOR FUNCTIONS OF SPASTIC RATS WITH BRAIN DAMAGE
M Gyimesi, A Horvath, D Turos, M Penzes, C Kurdi, A Szabo, M Kovacs, ...
INTERNATIONAL JOURNAL OF STROKE 15 (1_ SUPPL), 266-266, 2020
2020
3D Movement Analysis using Deep Learning Algorithms Reveals Alterations in Motor Functions After Neurological Injuries in RAT Spasticity Model
D Túrós, AI Horvath, M Gyimesi, A Malnasi-Csizmadia
Biophysical Journal 118 (3), 461a, 2020
2020
CRISPR/Cas9 genome editing repairs a novel ACTN2 mutation and prevents the disease phenotype in human iPSC-derived cardiomyocytes and engineered heart tissue
M Prondzynski, M Lemoine, A Horvath, E Krämer, ATL Zech, S Laufer, ...
Journal of Molecular and Cellular Cardiology 120, 7, 2018
2018
Properties of the sodium-calcium exchanger and the Na+/K+-ATPase in human induced pluripotent stem cell-derived cardiomyocytes
A Horvath, K Gurr, D Ismaili, I Mannhardt, B Ulmer, A Hansen, A Varro, ...
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 109, 20-20, 2017
2017
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