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Nikhil R. Tasker
Nikhil R. Tasker
Verified email at pitt.edu
Title
Cited by
Cited by
Year
Biosynthesis, total synthesis, and biological profiles of Ergot alkaloids
NR Tasker, P Wipf
The Alkaloids: Chemistry and Biology 85, 1-112, 2021
302021
A Short Synthesis of Ergot Alkaloids and Evaluation of the 5-HT1/2 Receptor Selectivity of Lysergols and Isolysergols
NR Tasker, P Wipf
Organic Letters 24 (40), 7255-7259, 2022
172022
Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors
NR Tasker, EJ Rastelli, JC Burnett, ER Sharlow, JS Lazo, P Wipf
Bioorganic & medicinal chemistry letters 29 (16), 2008-2015, 2019
142019
In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors
NR Tasker, EJ Rastelli, IK Blanco, JC Burnett, ER Sharlow, JS Lazo, ...
Organic & Biomolecular Chemistry 17 (9), 2448-2466, 2019
142019
Next-generation cell-active inhibitors of the undrugged oncogenic PTP4A3 phosphatase
JS Lazo, IK Blanco, NR Tasker, EJ Rastelli, JC Burnett, SR Garrott, ...
Journal of Pharmacology and Experimental Therapeutics 371 (3), 652-662, 2019
112019
Credentialing and pharmacologically targeting PTP4A3 phosphatase as a molecular target for ovarian cancer
JS Lazo, ER Sharlow, R Cornelison, DJ Hart, DC Llaneza, AJ Mendelson, ...
Biomolecules 11 (7), 969, 2021
92021
Structure of the complex of an iminopyridinedione protein tyrosine phosphatase 4a3 phosphatase inhibitor with human serum albumin
MP Czub, AM Boulton, EJ Rastelli, NR Tasker, TS Maskrey, IK Blanco, ...
Molecular Pharmacology 98 (6), 648-657, 2020
82020
Biological studies of clavine alkaloids targeting CNS receptors
NR Tasker, EJ Pazur, P Wipf
Frontiers in Psychiatry 14, 1286941, 2023
32023
Photoflow preparation of PTP4A3 inhibitors, and concise total syntheses of ergot and clavine alkaloids
NR Tasker
University of Pittsburgh, 2023
22023
Concise total syntheses of lysergene, lysergine, isolysergine and festuclavine
NR Tasker, P Wipf
ARKIVOC 2, S1-S13, 2024
12024
C3-Functionalization of indoles with α-heteroaryl-substituted methyl alcohols
EJ Pazur, NR Tasker, P Wipf
Organic & Biomolecular Chemistry 21 (43), 8651-8657, 2023
12023
Synthesis of Iso-Dimethyltryptamines and Biological Analysis in a Model of Light-Induced Retinal Degeneration
E Pazur, N Tasker, K Vainionpää, A Kalatanova, H Leinonen, P Wipf
2024
Direct C3-functionalization of indoles with alpha-heteroaryl-substituted methyl alcohols via a metal-free hydrogen autotransfer-type reaction
E Pazur, N Tasker, P Wipf
2023
Shortest Synthesis of Lysergol and its Binding to 5-HT1/2Receptors
NR Tasker, P Wipf
Synfacts 19 (01), 0109, 2023
2023
In-flow photooxygenation of aminothienopyridinones generates novel ptp4a3 phosphatase inhibitors
JS Lazo, E Sharlow, P Wipf, N Tasker, E Rastelli
US Patent App. 17/309,259, 2022
2022
In-flow photooxygenation of aminothienopyridinones generates novel ptp4a3 phosphatase inhibitors
JS Lazo, E Sharlow, P Wipf, N Tasker, E Rastelli
US Patent App. 17/309,260, 2021
2021
Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin (vol 98, pg 648, 2020)
MP Czub, AM Boulton, EJ Rastelli, NR Tasker, TS Maskrey, IK Blanco, ...
MOLECULAR PHARMACOLOGY 98 (6), 781-781, 2020
2020
Small molecule PTP4A3 phosphatase inhibitors targeting acute myeloid leukemia
J Lazo, N Tasker, E Rastelli, P Wipf, E Sharlow
European Journal of Cancer 138, S55-S56, 2020
2020
Next Generation Potent Cell‐active Inhibitors of the Oncogenic PTP4A3 Phosphatase
IK Blanco, NR Tasker, EJ Rastelli, P Wipf, ER Sharlow, JS Lazo
The FASEB Journal 33 (S1), 674.11-674.11, 2019
2019
The Mechanism of Inhibition of the Undrugged Oncogenic Phosphatase PTP4A3 by a Novel Small Molecule JMS‐053
SR Garrott, IK Blanco, NR Tasker, EJ Rastelli, ER Sharlow, P Wipf, ...
The FASEB Journal 33 (S1), 674.14-674.14, 2019
2019
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