A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells Y Chen, CA Tristan, L Chen, VM Jovanovic, C Malley, PH Chu, S Ryu, ... Nature methods 18 (5), 528-541, 2021 | 94 | 2021 |
Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer KL Mine, N Shulzhenko, A Yambartsev, M Rochman, GFO Sanson, ... Nature communications 4 (1), 1806, 2013 | 90 | 2013 |
An essential role for DNA methyltransferase 3a in melanoma tumorigenesis T Deng, Y Kuang, L Wang, J Li, Z Wang, J Fei Biochemical and biophysical research communications 387 (3), 611-616, 2009 | 84 | 2009 |
ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming P Mishra, W Tang, V Putluri, TH Dorsey, F Jin, F Wang, D Zhu, L Amable, ... The Journal of clinical investigation 128 (1), 323-340, 2018 | 77 | 2018 |
The HMGN family of chromatin-binding proteins: dynamic modulators of epigenetic processes JE Kugler, T Deng, M Bustin Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1819 (7), 652-656, 2012 | 70 | 2012 |
HMGN1 modulates nucleosome occupancy and DNase I hypersensitivity at the CpG island promoters of embryonic stem cells T Deng, ZI Zhu, S Zhang, F Leng, S Cherukuri, L Hansen, ... Molecular and cellular biology 33 (16), 3377-3389, 2013 | 48 | 2013 |
Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers T Deng, ZI Zhu, S Zhang, Y Postnikov, D Huang, M Horsch, T Furusawa, ... Genome research 25 (9), 1295-1308, 2015 | 43 | 2015 |
Binding of HMGN proteins to cell specific enhancers stabilizes cell identity B He, T Deng, I Zhu, T Furusawa, S Zhang, W Tang, Y Postnikov, S Ambs, ... Nature communications 9 (1), 5240, 2018 | 38 | 2018 |
Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation T Deng, Y Postnikov, S Zhang, L Garrett, L Becker, I Rácz, SM Hölter, ... Nucleic Acids Research 45 (6), 3031-3045, 2017 | 38 | 2017 |
Scalable generation of sensory neurons from human pluripotent stem cells T Deng, VM Jovanovic, CA Tristan, C Weber, PH Chu, J Inman, S Ryu, ... Stem Cell Reports 18 (4), 1030-1047, 2023 | 25 | 2023 |
HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naive B cells S Zhang, I Zhu, T Deng, T Furusawa, M Rochman, MS Vacchio, ... Nucleic acids research 44 (15), 7144-7158, 2016 | 23 | 2016 |
Disruption of imprinting and aberrant embryo development in completely inbred embryonic stem cell‐derived mice T Deng, Y Kuang, D Zhang, L Wang, R Sun, G Xu, Z Wang, J Fei Development, growth & differentiation 49 (7), 603-610, 2007 | 22 | 2007 |
Epigenetic regulation of REX1 expression and chromatin binding specificity by HMGNs S Zhang, T Deng, W Tang, B He, T Furusawa, S Ambs, M Bustin Nucleic acids research 47 (9), 4449-4461, 2019 | 19 | 2019 |
H3K27ac nucleosomes facilitate HMGN localization at regulatory sites to modulate chromatin binding of transcription factors S Zhang, Y Postnikov, A Lobanov, T Furusawa, T Deng, M Bustin Communications biology 5 (1), 159, 2022 | 12 | 2022 |
Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion AR Snavely, K Heo, V Petrova, TSY Ho, X Huang, C Hermawan, R Kagan, ... Disease models & mechanisms 15 (12), dmm049358, 2022 | 8 | 2022 |
Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness S Ryu, C Weber, PH Chu, B Ernest, VM Jovanovic, T Deng, J Slamecka, ... Biofabrication 16 (1), 015016, 2023 | 3 | 2023 |
Scalable generation of pseudo-unipolar sensory neurons from human pluripotent stem cells T Deng, CA Tristan, C Weber, PH Chu, S Ryu, VM Jovanovic, ... BioRxiv, 2022.03. 24.485622, 2022 | 3 | 2022 |
Enhancing the fitness of embryoid bodies and organoids by chemical cytoprotection S Ryu, C Weber, PH Chu, CA Tristan, B Ernest, VM Jovanovic, T Deng, ... BioRxiv, 2022.03. 21.485225, 2022 | 2 | 2022 |
Nociceptor differentiation from human pluripotent stem cells I Singec, T Deng, A Simeonov US Patent App. 17/605,876, 2022 | 1 | 2022 |
H3K27 acetylated nucleosomes facilitate HMGN protein localization at regulatory sites to modulate the interaction of transcription factors with chromatin S Zhang, Y Postnikov, A Lobanov, T Furusawa, T Deng, M Bustin bioRxiv, 2021.05. 03.442466, 2021 | 1 | 2021 |