Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity D Shin, R Mukherjee, D Grewe, D Bojkova, K Baek, A Bhattacharya, ... Nature 587 (7835), 657-662, 2020 | 924 | 2020 |
Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 383 | 2020 |
Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease CDL Miklós Békés, Gerbrand J. van der Heden van Noort, Reggy Ekkebus, Huib ... Molecular Cell 62 (4), 572-585, 2016 | 138 | 2016 |
Non-hydrolyzable Diubiquitin Probes Reveal Linkage- Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets’ D Flierman, GJ van der Heden van Noort, R Ekkebus, PP Geurink, ... Cell Chemical Biology 23 (4), 472-482, 2016 | 108 | 2016 |
An RNA virus hijacks an incognito function of a DNA repair enzyme R Virgen-Slane, JM Rozovics, KD Fitzgerald, T Ngo, W Chou, ... Proceedings of the National Academy of Sciences 109 (36), 14634-14639, 2012 | 102 | 2012 |
Synthesis of mono-ADP-ribosylated oligopeptides using ribosylated amino acid building blocks GJ van der Heden van Noort, MG van der Horst, HS Overkleeft, ... Journal of the American Chemical Society 132 (14), 5236-5240, 2010 | 66 | 2010 |
Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection R Mukherjee, A Bhattacharya, D Bojkova, AR Mehdipour, D Shin, ... Journal of Biological Chemistry 297 (2), 2021 | 52 | 2021 |
Stereoselective ribosylation of amino acids HAV Kistemaker, GJ van der Heden van Noort, HS Overkleeft, ... Organic letters 15 (9), 2306-2309, 2013 | 51 | 2013 |
Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: Towards synthetic epitope-based vaccines JJ Weterings, S Khan, GJ van der Heden, JW Drijfhout, CJM Melief, ... Bioorganic & medicinal chemistry letters 16 (12), 3258-3261, 2006 | 39 | 2006 |
Modification of picornavirus genomic RNA using ‘click’chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA MA Langereis, Q Feng, FHT Nelissen, R Virgen-Slane, ... Nucleic acids research 42 (4), 2473-2482, 2014 | 38 | 2014 |
2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation JJ Weterings, S Khan, CJM Melief, HS Overkleeft, SH van der Burg, ... Bioorganic & medicinal chemistry letters 19 (8), 2249-2251, 2009 | 32 | 2009 |
Ribosylation of adenosine: an orthogonally protected building block for the synthesis of ADP-ribosyl oligomers GJ van der Heden van Noort, HS Overkleeft, GA van der Marel, ... Organic Letters 13 (11), 2920-2923, 2011 | 31 | 2011 |
A general approach towards triazole‐linked adenosine diphosphate ribosylated peptides and proteins Q Liu, HAV Kistemaker, S Bhogaraju, I Dikic, HS Overkleeft, ... Angewandte Chemie International Edition 57 (6), 1659-1662, 2018 | 30 | 2018 |
DNA-triggered dye transfer on a quantum dot J Michaelis, GJ van der Heden van Noort, O Seitz Bioconjugate Chemistry 25 (1), 18-23, 2014 | 30 | 2014 |
Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection D Shin, A Bhattacharya, YL Cheng, MC Alonso, AR Mehdipour, ... Elife 9, e58277, 2020 | 28 | 2020 |
A Versatile One-Pot Procedure to Phosphate Monoesters and Pyrophosphates Using Di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite GJ van der Heden van Noort, CP Verhagen, MG van der Horst, ... Organic Letters 10 (20), 4461-4464, 2008 | 28 | 2008 |
Generation of the UFM1 Toolkit for Profiling UFM1‐Specific Proteases and Ligases KF Witting, GJ van der Heden van Noort, C Kofoed, C Talavera Ormeño, ... Angewandte Chemie 130 (43), 14360-14364, 2018 | 27 | 2018 |
Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler J Liwocha, DT Krist, GJ van der Heden van Noort, FM Hansen, VH Truong, ... Nature chemical biology 17 (3), 272-279, 2021 | 26 | 2021 |
Synthesis of nucleotidylated poliovirus VPg proteins GJ van der Heden van Noort, HS Overkleeft, GA van der Marel, ... The Journal of Organic Chemistry 75 (16), 5733-5736, 2010 | 25 | 2010 |
Synthesis of poly-ubiquitin chains using a bifunctional ubiquitin monomer GJ van der Heden van Noort, R Kooij, PR Elliott, D Komander, H Ovaa Organic letters 19 (24), 6490-6493, 2017 | 23 | 2017 |