Chris Waudby
Chris Waudby
UCL School of Pharmacy
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Cited by
Cited by
An analytical solution to the kinetics of breakable filament assembly
TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ...
Science 326 (5959), 1533-1537, 2009
Atomic structure and hierarchical assembly of a cross-β amyloid fibril
AWP Fitzpatrick, GT Debelouchina, MJ Bayro, DK Clare, MA Caporini, ...
Proceedings of the National Academy of Sciences 110 (14), 5468-5473, 2013
Mechanosensitive self-replication driven by self-organization
JMA Carnall, CA Waudby, AM Belenguer, MCA Stuart, JJP Peyralans, ...
Science 327 (5972), 1502-1506, 2010
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
Structure and properties of a complex of α-synuclein and a single-domain camelid antibody
EJ De Genst, T Guilliams, J Wellens, EM O'day, CA Waudby, S Meehan, ...
Journal of molecular biology 402 (2), 326-343, 2010
Two-dimensional NMR lineshape analysis
CA Waudby, A Ramos, LD Cabrita, J Christodoulou
Scientific reports 6 (1), 24826, 2016
Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ...
Biophysical journal 101 (7), 1681-1689, 2011
The interaction of αB-crystallin with mature α-synuclein amyloid fibrils inhibits their elongation
CA Waudby, TPJ Knowles, GL Devlin, JN Skepper, H Ecroyd, JA Carver, ...
Biophysical journal 98 (5), 843-851, 2010
A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding
LD Cabrita, AME Cassaignau, HMM Launay, CA Waudby, T Wlodarski, ...
Nature Structural & Molecular Biology 23 (4), 278-285, 2016
Hsp90 inhibits α-synuclein aggregation by interacting with soluble oligomers
S Daturpalli, CA Waudby, S Meehan, SE Jackson
Journal of molecular biology 425 (22), 4614-4628, 2013
On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with Congo red and lacmoid
C Lendel, CW Bertoncini, N Cremades, CA Waudby, M Vendruscolo, ...
Biochemistry 48 (35), 8322-8334, 2009
Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, ...
PloS one 5 (10), e13481, 2010
Nature and regulation of protein folding on the ribosome
CA Waudby, CM Dobson, J Christodoulou
Trends in biochemical sciences 44 (11), 914-926, 2019
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLoS computational biology 7 (10), e1002169, 2011
In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells
CA Waudby, C Camilloni, AWP Fitzpatrick, LD Cabrita, CM Dobson, ...
PloS one 8 (8), e72286, 2013
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein
R Porcari, C Proukakis, CA Waudby, B Bolognesi, PP Mangione, ...
Journal of Biological Chemistry 290 (4), 2395-2404, 2015
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein
R Porcari, C Proukakis, CA Waudby, B Bolognesi, PP Mangione, ...
Journal of Biological Chemistry 290 (4), 2395-2404, 2015
Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor
A Deckert, CA Waudby, T Wlodarski, AS Wentink, X Wang, JP Kirkpatrick, ...
Proceedings of the National Academy of Sciences 113 (18), 5012-5017, 2016
D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile
S Valleix, G Verona, N Jourde-Chiche, B NÚdelec, PP Mangione, ...
Nature communications 7 (1), 10353, 2016
Protein folding on the ribosome studied using NMR spectroscopy
CA Waudby, H Launay, LD Cabrita, J Christodoulou
Progress in nuclear magnetic resonance spectroscopy 74, 57-75, 2013
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