| The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype S Zhou, JD Schuetz, KD Bunting, AM Colapietro, J Sampath, JJ Morris, ... Nature medicine 7 (9), 1028-1034, 2001 | 3015 | 2001 |
| Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression P Kuehl, J Zhang, Y Lin, J Lamba, M Assem, J Schuetz, PB Watkins, ... Nature genetics 27 (4), 383-391, 2001 | 2689 | 2001 |
| Identification of functionally variant MDR1 alleles among European Americans and African Americans RB Kim, BF Leake, EF Choo, GK Dresser, SV Kubba, UI Schwarz, ... Clinical Pharmacology & Therapeutics 70 (2), 189-199, 2001 | 1292 | 2001 |
| The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme P Krishnamurthy, DD Ross, T Nakanishi, K Bailey-Dell, S Zhou, ... Journal of Biological Chemistry 279 (23), 24218-24225, 2004 | 875 | 2004 |
| MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs JD Schuetz, MC Connelly, D Sun, SG Paibir, PM Flynn, RV Srinivas, ... Nature medicine 5 (9), 1048-1051, 1999 | 734 | 1999 |
| Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo S Zhou, JJ Morris, Y Barnes, L Lan, JD Schuetz, BP Sorrentino Proceedings of the National Academy of Sciences 99 (19), 12339-12344, 2002 | 712 | 2002 |
| Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. JC Kolars, P Schmiedlin-Ren, JD Schuetz, C Fang, PB Watkins The Journal of clinical investigation 90 (5), 1871-1878, 1992 | 671 | 1992 |
| Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. EG Schuetz, WT Beck, JD Schuetz Molecular pharmacology 49 (2), 311-318, 1996 | 670 | 1996 |
| Mrp4 confers resistance to topotecan and protects the brain from chemotherapy M Leggas, M Adachi, GL Scheffer, D Sun, P Wielinga, G Du, KE Mercer, ... Molecular and cellular biology 24 (17), 7612-7621, 2004 | 516 | 2004 |
| Role of ABCG2/BCRP in biology and medicine P Krishnamurthy, JD Schuetz Annu. Rev. Pharmacol. Toxicol. 46, 381-410, 2006 | 470 | 2006 |
| Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration RM Perciavalle, DP Stewart, B Koss, J Lynch, S Milasta, M Bathina, ... Nature cell biology 14 (6), 575-583, 2012 | 460 | 2012 |
| Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450 EG Schuetz, S Strom, K Yasuda, V Lecureur, M Assem, C Brimer, ... Journal of Biological Chemistry 276 (42), 39411-39418, 2001 | 451 | 2001 |
| Identification of a mammalian mitochondrial porphyrin transporter PC Krishnamurthy, G Du, Y Fukuda, D Sun, J Sampath, KE Mercer, ... Nature 443 (7111), 586-589, 2006 | 424 | 2006 |
| Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro PJ Houghton, GS Germain, FC Harwood, JD Schuetz, CF Stewart, ... Cancer research 64 (7), 2333-2337, 2004 | 423 | 2004 |
| High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter C Özvegy-Laczka, T Hegedűs, G Várady, O Ujhelly, JD Schuetz, A Varadi, ... Molecular pharmacology 65 (6), 1485-1495, 2004 | 405 | 2004 |
| Transcriptional control of intestinal cytochrome P-4503A by 1α, 25-dihydroxy vitamin D3 KE Thummel, C Brimer, K Yasuda, J Thottassery, T Senn, Y Lin, ... Molecular Pharmacology 60 (6), 1399-1406, 2001 | 402 | 2001 |
| A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. EY Krynetski, JD Schuetz, AJ Galpin, CH Pui, MV Relling, WE Evans Proceedings of the National Academy of Sciences 92 (4), 949-953, 1995 | 385 | 1995 |
| Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver JD Schuetz, DL Beach, PS Guzelian Pharmacogenetics and Genomics 4 (1), 11-20, 1994 | 369 | 1994 |
| Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4) N Zelcer, G Reid, P Wielinga, A Kuil, I van der Heijden, JD Schuetz, ... Biochemical Journal 371 (2), 361-367, 2003 | 368 | 2003 |
| Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir T Imaoka, H Kusuhara, M Adachi, JD Schuetz, K Takeuchi, Y Sugiyama Molecular pharmacology 71 (2), 619-627, 2007 | 363 | 2007 |
