Doxorubicin-DNA adducts induce a non-topoisomerase II–mediated form of cell death LP Swift, A Rephaeli, A Nudelman, DR Phillips, SM Cutts Cancer research 66 (9), 4863-4871, 2006 | 411 | 2006 |
Human SNM1A and XPF–ERCC1 collaborate to initiate DNA interstrand cross-link repair AT Wang, B Sengerová, E Cattell, T Inagawa, JM Hartley, K Kiakos, ... Genes & development 25 (17), 1859-1870, 2011 | 170 | 2011 |
Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation RA Forrest, LP Swift, A Rephaeli, A Nudelman, KI Kimura, DR Phillips, ... Biochemical pharmacology 83 (12), 1602-1612, 2012 | 96 | 2012 |
Sequence specificity of adriamycin-DNA adducts in human tumor cells SM Cutts, LP Swift, A Rephaeli, A Nudelman, DR Phillips Molecular cancer therapeutics 2 (7), 661-670, 2003 | 70 | 2003 |
Activation of adriamycin by the pH-dependent formaldehyde-releasing prodrug hexamethylenetetramine LP Swift, SM Cutts, A Rephaeli, A Nudelman, DR Phillips Molecular cancer therapeutics 2 (2), 189-198, 2003 | 63 | 2003 |
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification HT Baddock, S Brolih, Y Yosaatmadja, M Ratnaweera, M Bielinski, ... Nucleic acids research 50 (3), 1484-1500, 2022 | 54 | 2022 |
The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity LP Swift, SM Cutts, A Nudelman, I Levovich, A Rephaeli, DR Phillips Cancer chemotherapy and pharmacology 61, 739-749, 2008 | 50 | 2008 |
Recent advances in understanding and exploiting the activation of anthracyclines by formaldehyde SM Cutts, LP Swift, A Rephaeli, A Nudelman, DR Phillips Current Medicinal Chemistry-Anti-Cancer Agents 5 (5), 431-447, 2005 | 40 | 2005 |
XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: Suitability as a biomarker for patient selection SB Hatch, LP Swift, S Caporali, R Carter, EJ Hill, TP MacGregor, S D'Atri, ... International journal of cancer 134 (6), 1495-1503, 2014 | 28 | 2014 |
Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate SM Cutts, LP Swift, V Pillay, RA Forrest, A Nudelman, A Rephaeli, ... Molecular Cancer Therapeutics 6 (4), 1450-1459, 2007 | 24 | 2007 |
Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species I Levovich, A Nudelman, G Berkovitch, LP Swift, SM Cutts, DR Phillips, ... Cancer chemotherapy and pharmacology 62, 471-482, 2008 | 23 | 2008 |
Structural requirements for the formation of anthracycline-DNA adducts SM Cutts, BS Parker, LP Swift, KI Kimura, DR Phillips Anti-cancer drug design 15 (5), 373-386, 2000 | 14 | 2000 |
The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts RA Forrest, LP Swift, BJ Evison, A Rephaeli, A Nudelman, DR Phillips, ... Cancer chemotherapy and pharmacology 71, 809-816, 2013 | 11 | 2013 |
Barminomycin, a model for the development of new anthracyclines K Kimura, DMS Spencer, R Bilardi, LP Swift, AJ Box, RTC Brownlee, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2010 | 8 | 2010 |
Analysis of DNA interstrand cross-links and their repair by modified comet assay LP Swift, L Castle, PJ McHugh DNA electrophoresis: Methods and protocols, 79-88, 2020 | 6 | 2020 |
N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells VL Emms, LA Lewis, L Beja, NFA Bulman, E Pires, FW Muskett, ... Chemical Science 14 (44), 12498-12505, 2023 | 3 | 2023 |
Enhancing the Anti-cancer Activity of Adriamycin LP Swift La Trobe University, 2004 | 1 | 2004 |
Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target M Bielinski, LR Henderson, Y Yosaatmadja, LP Swift, HT Baddock, ... Chemical Science, 2024 | | 2024 |
SNM1A (DCLRE1A) is crucial for efficient repair of complex DNA breaks in human cells P McHugh, L Swift, BC Lagerholm, H Baddock, L Henderson, ... | | 2023 |
SNM1A (DCLRE1A) is crucial for efficient repair of complex DNA breaks in human cells LP Swift, BC Lagerholm, HT Baddock, LR Henderson, M Ratnaweera, ... bioRxiv, 2022.07. 21.500940, 2022 | | 2022 |