Kate E Lawlor
Kate E Lawlor
Group Head, Cell Death and Inflammatory Signalling, Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research and Adjunct Research Fellow, Department of Molecular and Translational Science, Monash University
Verified email at - Homepage
Cited by
Cited by
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
H Stanton, FM Rogerson, CJ East, SB Golub, KE Lawlor, CT Meeker, ...
Nature 434 (7033), 648-652, 2005
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
KE Lawlor, N Khan, A Mildenhall, M Gerlic, BA Croker, AA D’Cruz, C Hall, ...
Nature communications 6, 6282, 2015
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ...
Cell 157 (5), 1175-1188, 2014
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
JE Vince, WWL Wong, I Gentle, KE Lawlor, R Allam, L O'reilly, K Mason, ...
Immunity 36 (2), 215-227, 2012
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Nez, ...
Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017
FcγRIIb controls bone marrow plasma cell persistence and apoptosis
Z Xiang, AJ Cutler, RJ Brownlie, K Fairfax, KE Lawlor, E Severinson, ...
Nature immunology 8 (4), 419, 2007
TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
KR Balka, C Louis, TL Saunders, AM Smith, DJ Calleja, DB D’Silva, ...
Cell Reports 31 (1), 107492, 2020
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
JA Rickard, H Anderton, N Etemadi, U Nachbur, M Darding, N Peltzer, ...
Elife 3, e03464, 2014
Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair
CB Little, CT Meeker, SB Golub, KE Lawlor, PJ Farmer, SM Smith, ...
The Journal of clinical investigation 117 (6), 1627-1636, 2007
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non‐apoptotic caspase‐8 is required for inflammasome priming
R Allam, KE Lawlor, ECW Yu, AL Mildenhall, DM Moujalled, RS Lewis, ...
EMBO reports 15 (9), 982-990, 2014
Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
N Lalaoui, SE Boyden, H Oda, GM Wood, DL Stone, D Chau, L Liu, ...
Nature 577 (7788), 103-108, 2020
Distinct cell-specific control of autoimmunity and infection by FcγRIIb
RJ Brownlie, KE Lawlor, HA Niederer, AJ Cutler, Z Xiang, MR Clatworthy, ...
Journal of Experimental Medicine 205 (4), 883-895, 2008
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and-7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation
JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ...
Cell Reports 25 (9), 2339-2353. e4, 2018
TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1
DM Moujalled, WD Cook, T Okamoto, J Murphy, KE Lawlor, JE Vince, ...
Cell death & disease 4 (1), e465, 2014
Severe inflammatory arthritis and lymphadenopathy in the absence of TNF
IK Campbell, K O’Donnell, KE Lawlor, IP Wicks
The Journal of clinical investigation 107 (12), 1519-1527, 2001
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner
WWL Wong, JE Vince, N Lalaoui, KE Lawlor, D Chau, A Bankovacki, ...
Blood 123 (16), 2562-2572, 2014
IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic syndrome
AJ Murphy, MJ Kraakman, HL Kammoun, D Dragoljevic, MKS Lee, ...
Cell metabolism 23 (1), 155-164, 2016
Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation
PJ Egan, KE Lawlor, WS Alexander, IP Wicks
The Journal of clinical investigation 111 (6), 915-924, 2003
Critical role for granulocyte colony-stimulating factor in inflammatory arthritis
KE Lawlor, IK Campbell, D Metcalf, K O'Donnell, A van Nieuwenhuijze, ...
Proceedings of the National Academy of Sciences 101 (31), 11398-11403, 2004
Ambiguities in NLRP3 inflammasome regulation: is there a role for mitochondria?
KE Lawlor, JE Vince
Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (4), 1433-1440, 2014
The system can't perform the operation now. Try again later.
Articles 1–20