| Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly (lactic acid) microspheres for the treatment of glaucoma B Chiang, YC Kim, AC Doty, HE Grossniklaus, SP Schwendeman, ... Journal of Controlled Release 228, 48-57, 2016 | 89 | 2016 |
| Mechanisms of in vivo release of triamcinolone acetonide from PLGA microspheres AC Doty, DG Weinstein, K Hirota, KF Olsen, R Ackermann, Y Wang, ... Journal of Controlled Release 256, 19-25, 2017 | 80 | 2017 |
| Characterizing release mechanisms of leuprolide acetate-loaded PLGA microspheres for IVIVC development I: in vitro evaluation K Hirota, AC Doty, R Ackermann, J Zhou, KF Olsen, MR Feng, Y Wang, ... Journal of controlled release 244, 302-313, 2016 | 70 | 2016 |
| Discovery of potent and orally available bicyclo [1.1. 1] pentane-derived indoleamine-2, 3-dioxygenase 1 (IDO1) inhibitors Q Pu, H Zhang, L Guo, M Cheng, AC Doty, H Ferguson, X Fradera, ... ACS Medicinal Chemistry Letters 11 (8), 1548-1554, 2020 | 51 | 2020 |
| Discovery of amino-cyclobutarene-derived indoleamine-2, 3-dioxygenase 1 (IDO1) inhibitors for cancer immunotherapy H Zhang, K Liu, Q Pu, A Achab, MJ Ardolino, M Cheng, Y Deng, AC Doty, ... ACS medicinal chemistry letters 10 (11), 1530-1536, 2019 | 40 | 2019 |
| Phosphatidylinositol induces fluid phase formation and packing defects in phosphatidylcholine model membranes A Peng, DS Pisal, A Doty, SV Balu-Iyer Chemistry and physics of lipids 165 (1), 15-22, 2012 | 38 | 2012 |
| Mechanistic analysis of triamcinolone acetonide release from PLGA microspheres as a function of varying in vitro release conditions AC Doty, Y Zhang, DG Weinstein, Y Wang, S Choi, W Qu, S Mittal, ... European Journal of Pharmaceutics and Biopharmaceutics 113, 24-33, 2017 | 36 | 2017 |
| Validation of a cage implant system for assessing in vivo performance of long-acting release microspheres AC Doty, K Hirota, KF Olsen, N Sakamoto, R Ackermann, MR Feng, ... Biomaterials 109, 88-96, 2016 | 28 | 2016 |
| Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors D Li, Y Deng, A Achab, I Bharathan, BA Hopkins, W Yu, H Zhang, ... ACS medicinal chemistry letters 12 (3), 389-396, 2021 | 16 | 2021 |
| An imaging toolkit for physical characterization of long-acting pharmaceutical implants D Skomski, Z Liu, Y Su, CT John, A Doty, SP Forster, R Teller, SE Barrett, ... Journal of Pharmaceutical Sciences 109 (9), 2798-2811, 2020 | 8 | 2020 |
| Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1, 6-naphthyridine, or octahydro-1H-pyrrolo [3, 2-c] pyridine scaffold W Yu, Y Deng, D Sloman, D Li, K Liu, X Fradera, CA Lesburg, T Martinot, ... Bioorganic & Medicinal Chemistry Letters 49, 128314, 2021 | 7 | 2021 |
| SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors W Yu, Y Deng, B Hopkins, X Huang, D Sloman, H Zhang, D Li, ... Bioorganic & Medicinal Chemistry Letters 47, 128214, 2021 | 4 | 2021 |
| Formulation strategies to enable delivery of therapeutic peptides across cell membranes AC Doty, CM Jarvis, EV Munsell Approaching the Next Inflection in Peptide Therapeutics: Attaining Cell …, 2022 | 2 | 2022 |
| Mechanistic Analysis of In Vitro and In Vivo Drug Release from PLGA Microspheres. AC Doty | 2 | 2015 |
| Discovery and optimization of potent, selective, and orally available IDO1 heme-binding inhibitors featuring a novel A-pocket piece H Zhang, A Achab, M Ardolino, X Chai, M Cheng, Y Deng, A Doty, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | 1 | 2018 |
| RIG-I agonism promotes immune activation in syngeneic tumor model M Zielstorff, Y Chen, J Presland, A Byford, A Doty, E Munsell, C Parish, ... Cancer Research 82 (12_Supplement), 3143-3143, 2022 | | 2022 |
| Innovation in delivering synthetically challenging bicyclic arginase inhibitors to enhance immunotherapy D Li, H Zhang, TW Lyons, TA Martinot, A Achab, M Lu, LM Nogle, ... Cancer Research 81 (13_Supplement), 297-297, 2021 | | 2021 |
| Discovery of potent and structurally diverse IDO1 selective heme-displacing inhibitors from optimization of hits from a mass spectrometry based affinity (ALIS) screen Y Han, A Achab, C Andrews, J Ballard, I Bharathan, X Chai, P Chen, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| A Cage Implant System for Assessing In Vivo Controlled Release Performance of Long-Acting Release PLGA Microspheres A Doty, K Hirota, R Ackermann, K Olsen, R Feng, W Qu, Y Wang, S Choi, ... | | |
| Aqueous Remote Loading of Cationic Peptides in PLGA Microspheres M Giles, A Doty, SP Schwendeman | | |
