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Cigdem Sevim Bayrak
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Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities
LO Huang, A Rauch, E Mazzaferro, M Preuss, S Carobbio, CS Bayrak, ...
Nature Metabolism 3 (2), 228-243, 2021
752021
De novo variants in exomes of congenital heart disease patients identify risk genes and pathways
C Sevim Bayrak, P Zhang, M Tristani-Firouzi, BD Gelb, Y Itan
Genome medicine 12, 1-18, 2020
472020
RAG-3D: a search tool for RNA 3D substructures
M Zahran, C Sevim Bayrak, S Elmetwaly, T Schlick
Nucleic acids research 43 (19), 9474-9488, 2015
392015
Identification of discriminative gene-level and protein-level features associated with pathogenic gain-of-function and loss-of-function variants
CS Bayrak, D Stein, A Jain, K Chaudhary, GN Nadkarni, TT Van Vleck, ...
The American Journal of Human Genetics 108 (12), 2301-2318, 2021
242021
Using sequence signatures and kink-turn motifs in knowledge-based statistical potentials for RNA structure prediction
CS Bayrak, N Kim, T Schlick
Nucleic acids research 45 (9), 5414-5422, 2017
232017
Identifying disease-causing mutations in genomes of single patients by computational approaches
C Sevim Bayrak, Y Itan
Human Genetics 139, 769-776, 2020
152020
Dual graph partitioning highlights a small group of pseudoknot-containing RNA submotifs
S Jain, CS Bayrak, L Petingi, T Schlick
Genes 9 (8), 371, 2018
112018
A computational approach for detecting physiological homogeneity in the midst of genetic heterogeneity
P Zhang, A Cobat, YS Lee, Y Wu, CS Bayrak, C Boccon-Gibod, ...
The American Journal of Human Genetics 108 (6), 1012-1025, 2021
62021
Genome-wide prediction of pathogenic gain-and loss-of-function variants from ensemble learning of a diverse feature set
D Stein, Sevim Bayrak, Y Wu, ME Kars, PD Stenson, DN Cooper, ...
bioRxiv, 2022.06. 08.495288, 2022
32022
Conformational transitions in the Ramachandran space of amino acids using the dynamic rotational isomeric state (DRIS) model
CS Bayrak, B Erman
Molecular BioSystems 10 (3), 663-671, 2014
32014
Predicting most probable conformations of a given peptide sequence in the random coil state
CS Bayrak, B Erman
Molecular BioSystems 8 (11), 3010-3016, 2012
32012
Identifying novel high-impact rare disease-causing mutations, genes and pathways in exomes of Ashkenazi Jewish inflammatory bowel disease patients
Y Wu, K Gettler, M Giri, D Li, CS Bayrak, A Jain, P Maffucci, K Sabic, ...
medRxiv, 2020.07. 01.20143750, 2020
22020
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients
Y Wu, K Gettler, ME Kars, M Giri, D Li, CS Bayrak, P Zhang, A Jain, ...
Nature communications 14 (1), 2256, 2023
12023
Chemokine receptor 5 signaling in PFC mediates stress susceptibility in female mice
HY Lin, F Cathomas, L Li, RD Cuttoli, C Guevara, C Sevim Bayrak, ...
bioRxiv, 2023.08. 18.553789, 2023
12023
Identification of Discriminative Gene-level and Protein-level Features Associated with Gain-of-Function and Loss-of-Function Mutations
CS Bayrak, A Jain, D Stein, K Chaudhary, GN Nadkarni, T Van Vleck, ...
bioRxiv, 2021.01. 01.424981, 2021
12021
Patient Subtyping Analysis of Baseline Multi-omic Data Reveals Distinct Pre-immune States Predictive of Vaccination Responses
CS Bayrak, C Forst, DR Jones, D Gresham, S Pushalkar, S Wu, C Vogel, ...
Biorxiv: the Preprint Server for Biology, 2024
2024
Patient Subtyping Analysis of Baseline Multi-omic Data Reveals Distinct Pre-immune States Predictive of Vaccination Responses
C Sevim Bayrak, C Forst, DR Jones, DJJ Gresham, S Pushalkar, S Wu, ...
bioRxiv, 2024.01. 18.576213, 2024
2024
Genome-wide prediction of pathogenic gain-and loss-of-function variants from ensemble learning of a diverse feature set
D Stein, ME Kars, Y Wu, S Bayrak, PD Stenson, DN Cooper, ...
Genome Medicine 15 (1), 103, 2023
2023
Identifying shared genetic factors underlying epilepsy and congenital heart disease in Europeans
Y Wu, CS Bayrak, B Dong, S He, PD Stenson, DN Cooper, Y Itan, L Chen
Human Genetics 142 (2), 275-288, 2023
2023
A comprehensive knowledgebase of known and predicted human genetic variants associated with COVID-19 susceptibility and severity
ME Kars, D Stein, Sevim Bayrak, PD Stenson, DN Cooper, Y Itan
medRxiv, 2022.11. 03.22281867, 2022
2022
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