| Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments L Somsak, V Nagy, Z Hadady, T Docsa, P Gergely Current pharmaceutical design 9 (15), 1177-1189, 2003 | 251 | 2003 |
| New inhibitors of glycogen phosphorylase as potential antidiabetic agents L Somsák, K Czifrák, M Tóth, E Bokor, ED Chrysina, KM Alexacou, ... Current medicinal chemistry 15 (28), 2933-2983, 2008 | 217 | 2008 |
| C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential E Bokor, S Kun, D Goyard, M Toth, JP Praly, S Vidal, L Somsak Chemical Reviews 117 (3), 1687-1764, 2017 | 212 | 2017 |
| Carbanionic reactivity of the anomeric center in carbohydrates L Somsák Chemical reviews 101 (1), 81-136, 2001 | 206 | 2001 |
| Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of d-gluco-and d-xylopyranosylidene-spiro-(thio) hydantoins … L Somsák, L Kovács, M Tóth, E Ősz, L Szilágyi, Z Györgydeák, Z Dinya, ... Journal of medicinal chemistry 44 (17), 2843-2848, 2001 | 183 | 2001 |
| Advances in glycogen phosphorylase inhibitor design. NG Oikonomakos, L Somsak Current opinion in investigational drugs (London, England: 2000) 9 (4), 379-395, 2008 | 132 | 2008 |
| Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin E Ősz, L Somsák, L Szilágyi, L Kovács, T Docsa, B Tóth, P Gergely Bioorganic & medicinal chemistry letters 9 (10), 1385-1390, 1999 | 123 | 1999 |
| Kinetic and crystallographic studies on 2‐(β‐D‐glucopyranosyl)‐5‐methyl‐1, 3, 4‐oxadiazole,‐benzothiazole, and‐benzimidazole, inhibitors of muscle glycogen phosphorylase b … ED Chrysina, MN Kosmopoulou, C Tiraidis, R Kardakaris, N Bischler, ... Protein science 14 (4), 873-888, 2005 | 108 | 2005 |
| Glucose derived inhibitors of glycogen phosphorylase L Somsak Comptes Rendus Chimie 14 (2-3), 211-223, 2011 | 103 | 2011 |
| Synthesis of 1-(D-glucopyranosyl)-1, 2, 3-triazoles and their evaluation as glycogen phosphorylase inhibitors É Bokor, T Docsa, P Gergely, L Somsák Bioorganic & medicinal chemistry 18 (3), 1171-1180, 2010 | 101 | 2010 |
| Radical-mediated brominations at ring positions of carbohydrates L Somsák, RJ Ferrier Advances in carbohydrate chemistry and biochemistry 49, 37-92, 1991 | 98 | 1991 |
| Binding of N‐acetyl‐N ′‐β‐d‐glucopyranosyl urea and N‐benzoyl‐N ′‐β‐d‐glucopyranosyl urea to glycogen phosphorylase b Kinetic and … NG Oikonomakos, M Kosmopoulou, SE Zographos, DD Leonidas, ... European journal of biochemistry 269 (6), 1684-1696, 2002 | 97 | 2002 |
| Amide-1, 2, 3-triazole bioisosterism: the glycogen phosphorylase case ED Chrysina, É Bokor, KM Alexacou, MD Charavgi, GN Oikonomakos, ... Tetrahedron: Asymmetry 20 (6-8), 733-740, 2009 | 92 | 2009 |
| A simple method for the synthesis of acylated pyranoid glycals under aprotic conditions L Somsák, I Németh Journal of carbohydrate chemistry 12 (4-5), 679-684, 1993 | 92 | 1993 |
| Synthesis and structure–activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase M Tóth, S Kun, É Bokor, M Benltifa, G Tallec, S Vidal, T Docsa, P Gergely, ... Bioorganic & medicinal chemistry 17 (13), 4773-4785, 2009 | 90 | 2009 |
| Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition D Goyard, B Kónya, AS Chajistamatiou, ED Chrysina, J Leroy, S Balzarin, ... European Journal of Medicinal Chemistry 108, 444-454, 2016 | 88 | 2016 |
| Synthesis of N-(β-D-glucopyranosyl)-and N-(2-acetamido-2-deoxy-β-D-glucopyranosyl) amides as inhibitors of glycogen phosphorylase Z Györgydeák, Z Hadady, N Felföldi, A Krakomperger, V Nagy, M Tóth, ... Bioorganic & medicinal chemistry 12 (18), 4861-4870, 2004 | 88 | 2004 |
| A new, scalable preparation of a glucopyranosylidene-spiro-thiohydantoin: one of the best inhibitors of glycogen phosphorylases L Somsák, V Nagy Tetrahedron: Asymmetry 11 (8), 1719-1727, 2000 | 84 | 2000 |
| Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase b NG Oikonomakos, VT Skamnaki, E Ösz, L Szilágyi, L Somsák, T Docsa, ... Bioorganic & medicinal chemistry 10 (2), 261-268, 2002 | 73 | 2002 |
| Effect of glucopyranosylidene-spiro-thiohydantoin on glycogen metabolism in liver tissues of streptozotocin-induced and obese diabetic rats T Docsa, K Czifrák, C Hüse, L Somsák, P Gergely Molecular Medicine Reports 4 (3), 477-481, 2011 | 71 | 2011 |
Pál GergelyProfessor of Medical Chemistry, University of DebrecenVerified email at unideb.hu
