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László Somsák
László Somsák
Professor of Chemistry, University of Debrecen
Verified email at unideb.hu
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Cited by
Cited by
Year
Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments
L Somsák, V Nagy, Z Hadady, T Docsa, P Gergely
Current pharmaceutical design 9 (15), 1177-1189, 2003
2482003
New inhibitors of glycogen phosphorylase as potential antidiabetic agents
L Somsák, K Czifrák, M Tóth, E Bokor, ED Chrysina, KM Alexacou, ...
Current medicinal chemistry 15 (28), 2933-2983, 2008
2022008
Carbanionic reactivity of the anomeric center in carbohydrates
L Somsák
Chemical reviews 101 (1), 81-136, 2001
1782001
Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of d-gluco-and d-xylopyranosylidene-spiro-(thio) hydantoins …
L Somsák, L Kovács, M Tóth, E Ősz, L Szilágyi, Z Györgydeák, Z Dinya, ...
Journal of medicinal chemistry 44 (17), 2843-2848, 2001
1742001
C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential
E Bokor, S Kun, D Goyard, M Toth, JP Praly, S Vidal, L Somsak
Chemical Reviews 117 (3), 1687-1764, 2017
1422017
Advances in glycogen phosphorylase inhibitor design.
NG Oikonomakos, L Somsak
Current opinion in investigational drugs (London, England: 2000) 9 (4), 379-395, 2008
1252008
Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin
E Ősz, L Somsák, L Szilágyi, L Kovács, T Docsa, B Tóth, P Gergely
Bioorganic & medicinal chemistry letters 9 (10), 1385-1390, 1999
1111999
Kinetic and crystallographic studies on 2‐(β‐D‐glucopyranosyl)‐5‐methyl‐1, 3, 4‐oxadiazole,‐benzothiazole, and‐benzimidazole, inhibitors of muscle glycogen phosphorylase b …
ED Chrysina, MN Kosmopoulou, C Tiraidis, R Kardakaris, N Bischler, ...
Protein science 14 (4), 873-888, 2005
1002005
Radical-mediated brominations at ring positions of carbohydrates
L Somsák, RJ Ferrier
Advances in carbohydrate chemistry and biochemistry 49, 37-92, 1991
961991
Glucose derived inhibitors of glycogen phosphorylase
L Somsak
Comptes Rendus Chimie 14 (2-3), 211-223, 2011
942011
Synthesis of 1-(D-glucopyranosyl)-1, 2, 3-triazoles and their evaluation as glycogen phosphorylase inhibitors
É Bokor, T Docsa, P Gergely, L Somsák
Bioorganic & medicinal chemistry 18 (3), 1171-1180, 2010
912010
Binding of N‐acetyl‐N ′‐β‐d‐glucopyranosyl urea and N‐benzoyl‐N ′‐β‐d‐glucopyranosyl urea to glycogen phosphorylase b Kinetic and …
NG Oikonomakos, M Kosmopoulou, SE Zographos, DD Leonidas, ...
European journal of biochemistry 269 (6), 1684-1696, 2002
892002
Synthesis and structure–activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase
M Tóth, S Kun, É Bokor, M Benltifa, G Tallec, S Vidal, T Docsa, P Gergely, ...
Bioorganic & medicinal chemistry 17 (13), 4773-4785, 2009
832009
Amide-1, 2, 3-triazole bioisosterism: the glycogen phosphorylase case
ED Chrysina, É Bokor, KM Alexacou, MD Charavgi, GN Oikonomakos, ...
Tetrahedron: Asymmetry 20 (6-8), 733-740, 2009
832009
A simple method for the synthesis of acylated pyranoid glycals under aprotic conditions
L Somsák, I Németh
Journal of carbohydrate chemistry 12 (4-5), 679-684, 1993
831993
A new, scalable preparation of a glucopyranosylidene-spiro-thiohydantoin: one of the best inhibitors of glycogen phosphorylases
L Somsák, V Nagy
Tetrahedron: Asymmetry 11 (8), 1719-1727, 2000
772000
Synthesis of N-(β-D-glucopyranosyl)-and N-(2-acetamido-2-deoxy-β-D-glucopyranosyl) amides as inhibitors of glycogen phosphorylase
Z Györgydeák, Z Hadady, N Felföldi, A Krakomperger, V Nagy, M Tóth, ...
Bioorganic & medicinal chemistry 12 (18), 4861-4870, 2004
762004
Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase b
NG Oikonomakos, VT Skamnaki, E Ösz, L Szilágyi, L Somsák, T Docsa, ...
Bioorganic & medicinal chemistry 10 (2), 261-268, 2002
692002
Effect of glucopyranosylidene-spiro-thiohydantoin on glycogen metabolism in liver tissues of streptozotocin-induced and obese diabetic rats
T Docsa, K Czifrák, C Hüse, L Somsák, P Gergely
Molecular Medicine Reports 4 (3), 477-481, 2011
662011
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition
D Goyard, B Kónya, AS Chajistamatiou, ED Chrysina, J Leroy, S Balzarin, ...
European Journal of Medicinal Chemistry 108, 444-454, 2016
632016
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