| Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR J Cehajic-Kapetanovic, K Xue, C Martinez-Fernandez de la Camara, ... Nature medicine 26 (3), 354-359, 2020 | 292 | 2020 |
| Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography MD Fischer, G Huber, SC Beck, N Tanimoto, R Muehlfriedel, E Fahl, ... PloS one 4 (10), e7507, 2009 | 249 | 2009 |
| Restoration of cone vision in the CNGA3−/− mouse model of congenital complete lack of cone photoreceptor function S Michalakis, R Mühlfriedel, N Tanimoto, V Krishnamoorthy, S Koch, ... Molecular therapy 18 (12), 2057-2063, 2010 | 233 | 2010 |
| Spectral domain optical coherence tomography in mouse models of retinal degeneration G Huber, SC Beck, C Grimm, A Sahaboglu-Tekgoz, F Paquet-Durand, ... Investigative ophthalmology & visual science 50 (12), 5888-5895, 2009 | 214 | 2009 |
| Heregulin ameliorates the dystrophic phenotype in mdx mice TOB Krag, S Bogdanovich, CJ Jensen, MD Fischer, J Hansen-Schwartz, ... Proceedings of the National Academy of Sciences 101 (38), 13856-13860, 2004 | 209 | 2004 |
| Immune responses to retinal gene therapy using adeno-associated viral vectors–Implications for treatment success and safety K Bucher, E Rodríguez-Bocanegra, D Dauletbekov, MD Fischer Progress in retinal and eye research 83, 100915, 2021 | 164 | 2021 |
| Safety and vision outcomes of subretinal gene therapy targeting cone photoreceptors in achromatopsia: a nonrandomized controlled trial MD Fischer, S Michalakis, B Wilhelm, D Zobor, R Muehlfriedel, S Kohl, ... JAMA ophthalmology 138 (6), 643-651, 2020 | 158 | 2020 |
| Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA NJ Parkinson, S Maslau, B Ferneyhough, G Zhang, L Gregory, D Buck, ... Genome research 22 (1), 125-133, 2012 | 153 | 2012 |
| AAV8 can induce innate and adaptive immune response in the primate eye FF Reichel, DL Dauletbekov, R Klein, T Peters, GA Ochakovski, IP Seitz, ... Molecular Therapy 25 (12), 2648-2660, 2017 | 141 | 2017 |
| Expression profiling reveals metabolic and structural components of extraocular muscles MD Fischer, JR Gorospe, E Felder, S Bogdanovich, F Pedrosa-Domellof, ... Physiological Genomics 9 (2), 71-84, 2002 | 136 | 2002 |
| A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa F Paquet-Durand, S Beck, S Michalakis, T Goldmann, G Huber, ... Human molecular genetics 20 (5), 941-947, 2011 | 130 | 2011 |
| Codon-optimized RPGR improves stability and efficacy of AAV8 gene therapy in two mouse models of X-linked retinitis pigmentosa MD Fischer, ME McClements, CMF de la Camara, JS Bellingrath, ... Molecular Therapy 25 (8), 1854-1865, 2017 | 124 | 2017 |
| Retinal gene therapy: surgical vector delivery in the translation to clinical trials GA Ochakovski, KU Bartz-Schmidt, MD Fischer Frontiers in neuroscience 11, 174, 2017 | 112 | 2017 |
| Definition of the unique human extraocular muscle allotype by expression profiling MD Fischer, MT Budak, M Bakay, JR Gorospe, D Kjellgren, ... Physiological genomics 22 (3), 283-291, 2005 | 104 | 2005 |
| Vision tests in the mouse: Functional phenotyping with electroretinography N Tanimoto, RL Muehlfriedel, MD Fischer, E Fahl, P Humphries, M Biel, ... Front Biosci 14, 2730-2737, 2009 | 93 | 2009 |
| Superior retinal gene transfer and biodistribution profile of subretinal versus intravitreal delivery of AAV8 in nonhuman primates IP Seitz, S Michalakis, B Wilhelm, FF Reichel, GA Ochakovski, E Zrenner, ... Investigative ophthalmology & visual science 58 (13), 5792-5801, 2017 | 90 | 2017 |
| Efficacy and safety of retinal gene therapy using adeno-associated virus vector for patients with choroideremia: a randomized clinical trial MD Fischer, GA Ochakovski, B Beier, IP Seitz, Y Vaheb, C Kortuem, ... JAMA ophthalmology 137 (11), 1247-1254, 2019 | 83 | 2019 |
| Humoral immune response after intravitreal but not after subretinal AAV8 in primates and patients FF Reichel, T Peters, B Wilhelm, M Biel, M Ueffing, B Wissinger, ... Investigative Ophthalmology & Visual Science 59 (5), 1910-1915, 2018 | 77 | 2018 |
| A new method to monitor visual field defects caused by photoreceptor degeneration by quantitative optical coherence tomography MD Fischer, JC Fleischhauer, MC Gillies, FK Sutter, H Helbig, ... Investigative ophthalmology & visual science 49 (8), 3617-3621, 2008 | 76 | 2008 |
| Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model GB Jaissle, CA May, SA Van De Pavert, A Wenzel, E Claes-May, A Gießl, ... Graefe's Archive for Clinical and Experimental Ophthalmology 248 (8), 1063-1070, 2010 | 70 | 2010 |
Robert E MacLarenUniversity of OxfordVerified email at eye.ox.ac.uk
