| Novel Inhibitors of Protein Arginine Deiminase with Potential Activity in Multiple Sclerosis Animal Model L Wei, E Wasilewski, SK Chakka, AM Bello, MA Moscarello, LP Kotra Journal of medicinal chemistry, 2013 | 64 | 2013 |
| Passive membrane permeability of macrocycles can be controlled by exocyclic amide bonds JL Hickey, S Zaretsky, MA St. Denis, S Kumar Chakka, MM Morshed, ... Journal of medicinal chemistry 59 (11), 5368-5376, 2016 | 60 | 2016 |
| Identification of novel class of falcipain-2 inhibitors as potential antimalarial agents SK Chakka, M Kalamuddin, S Sundararaman, L Wei, S Mundra, ... Bioorganic & medicinal chemistry 23 (9), 2221-2240, 2015 | 40 | 2015 |
| Synthesis of tetrahydroisoquinoline (TIQ)–oxazoline ligands and their application in enantioselective Henry reactions RB Kawthekar, SK Chakka, V Francis, PG Andersson, HG Kruger, ... Tetrahedron: Asymmetry 21 (7), 846-852, 2010 | 35 | 2010 |
| Synthesis of tetrahydroisoquinoline-diamine ligands and their application in asymmetric transfer hydrogenation BK Peters, SK Chakka, T Naicker, GEM Maguire, HG Kruger, ... Tetrahedron: Asymmetry 21 (6), 679-687, 2010 | 33 | 2010 |
| Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors S Arora, N Sinha, P Nair, SK Chakka, A Hajare, A Reddy, P Patil, ... US Patent 8,338,450, 2012 | 30 | 2012 |
| Synthesis and Screening of C1‐Substituted Tetrahydroisoquinoline Derivatives for Asymmetric Transfer Hydrogenation Reactions SK Chakka, PG Andersson, GEM Maguire, HG Kruger, T Govender European Journal of Organic Chemistry 2010 (5), 972-980, 2010 | 29 | 2010 |
| A novel class of Plasmodial ClpP protease inhibitors as potential antimalarial agents S Mundra, V Thakur, AM Bello, S Rathore, M Asad, L Wei, J Yang, ... Bioorganic & Medicinal Chemistry 25 (20), 5662-5677, 2017 | 28 | 2017 |
| Iridium-catalyzed asymmetric hydrogenation of olefins using TIQ phosphine–oxazoline ligands SK Chakka, BK Peters, PG Andersson, GEM Maguire, HG Kruger, ... Tetrahedron: Asymmetry 21 (18), 2295-2301, 2010 | 28 | 2010 |
| Structure–activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias MK Purohit, SK Chakka, I Scovell, A Neschadim, AM Bello, N Salum, ... Bioorganic & Medicinal Chemistry 22 (9), 2739-2752, 2014 | 26 | 2014 |
| Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis A Sarswat, E Wasilewski, SK Chakka, AM Bello, AV Caprariello, ... Bioorganic & medicinal chemistry 25 (9), 2643-2656, 2017 | 23 | 2017 |
| Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR LM Stevers, M Wolter, GW Carlile, D Macdonald, L Richard, F Gielkens, ... Nature Communications 13 (1), 3586, 2022 | 14 | 2022 |
| Asymmetric conjugate addition of thioglycolate to a range of chalcones using tetrahydroisoquinoline (TIQ) N, N′-dioxide ligands SK Chakka, ZED Cele, SC Sosibo, V Francis, PI Arvidsson, HG Kruger, ... Tetrahedron: Asymmetry 23 (8), 616-622, 2012 | 10 | 2012 |
| Comparison of tetrahydroisoquinoline (TIQ) thiazole and oxazoline ligands for asymmetric Henry reactions SS Pawar, SK Chakka, PG Andersson, HG Kruger, GEM Maguire, ... South African Journal of Chemistry 65, 23-29, 2012 | 3 | 2012 |
| (R)-4-Phenyl-2-[(S)-1, 2, 3, 4-tetrahydroisoquinolin-3-yl]-4, 5-dihydro-1, 3-oxazole SK Chakka, T Govender, HG Kruger, GEM Maguire Acta Crystallographica Section E: Structure Reports Online 66 (7), o1818-o1818, 2010 | 3 | 2010 |
| 1, 7-Dimethylpentacyclo [5.4. 0.02, 6.03, 10.05, 9] undecane-8, 11-dione SK Chakka, OK Onajole, T Govender, GEM Maguire, H Su, HG Kruger Acta Crystallographica Section E: Structure Reports Online 66 (8), o1901-o1902, 2010 | 1 | 2010 |
| DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor AP Silvestri, Q Zhang, Y Ping, EW Muir, J Zhao, SK Chakka, G Wang, ... ACS Medicinal Chemistry Letters 14 (6), 820-826, 2023 | | 2023 |
| Abstract B018: The development of macrocyclic peptide Ras inhibitors K Josephson, A Silvestri, JL Fribourgh, WM Bray, B David, CC Hanna, ... Molecular Cancer Research 21 (5_Supplement), B018-B018, 2023 | | 2023 |
| [(1R, 3S)-6, 7-Dimethoxy-1-phenyl-1, 2, 3, 4-tetrahydroisoquinolin-3-yl] methanol 2.33-hydrate SK Chakka, MG McKay, T Govender, HG Kruger, GEM Maguire Acta Crystallographica Section E: Structure Reports Online 67 (3), o700-o700, 2011 | | 2011 |
| Synthesis of novel tetrahydroisoquinoline chiral ligands for application in asymmetric transfer hydrogenation. BK Peters | | 2010 |
