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Tumor-specific Th17-polarized cells eradicate large established melanoma P Muranski, A Boni, PA Antony, L Cassard, KR Irvine, A Kaiser, ... Blood, The Journal of the American Society of Hematology 112 (2), 362-373, 2008 | 1057 | 2008 |
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts SA Quezada, TR Simpson, KS Peggs, T Merghoub, J Vider, X Fan, ... Journal of Experimental Medicine 207 (3), 637-650, 2010 | 1048 | 2010 |
T helper 17 cells promote cytotoxic T cell activation in tumor immunity N Martin-Orozco, P Muranski, Y Chung, XO Yang, T Yamazaki, S Lu, ... Immunity 31 (5), 787-798, 2009 | 997 | 2009 |
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function M Sukumar, J Liu, Y Ji, M Subramanian, JG Crompton, Z Yu, ... The Journal of clinical investigation 123 (10), 4479-4488, 2013 | 992 | 2013 |
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling CM Paulos, C Wrzesinski, A Kaiser, CS Hinrichs, M Chieppa, L Cassard, ... The Journal of clinical investigation 117 (8), 2197-2204, 2007 | 655 | 2007 |
Naive tumor-specific CD4+ T cells differentiated in vivo eradicate established melanoma Y Xie, A Akpinarli, C Maris, EL Hipkiss, M Lane, EKM Kwon, P Muranski, ... Journal of Experimental Medicine 207 (3), 651-667, 2010 | 547 | 2010 |
Th17 cells are long lived and retain a stem cell-like molecular signature P Muranski, ZA Borman, SP Kerkar, CA Klebanoff, Y Ji, L Sanchez-Perez, ... Immunity 35 (6), 972-985, 2011 | 517 | 2011 |
Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity CS Hinrichs, ZA Borman, L Cassard, L Gattinoni, R Spolski, Z Yu, ... Proceedings of the National Academy of Sciences 106 (41), 17469-17474, 2009 | 485 | 2009 |
Essentials of Th17 cell commitment and plasticity P Muranski, NP Restifo Blood, The Journal of the American Society of Hematology 121 (13), 2402-2414, 2013 | 482 | 2013 |
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ... Nature 498 (7455), 506-510, 2013 | 451 | 2013 |
Increased intensity lymphodepletion and adoptive immunotherapy—how far can we go? P Muranski, A Boni, C Wrzesinski, DE Citrin, SA Rosenberg, R Childs, ... Nature clinical practice Oncology 3 (12), 668-681, 2006 | 434 | 2006 |
Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy CS Hinrichs, ZA Borman, L Gattinoni, Z Yu, WR Burns, J Huang, ... Blood, The Journal of the American Society of Hematology 117 (3), 808-814, 2011 | 390 | 2011 |
IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors SP Kerkar, RS Goldszmid, P Muranski, D Chinnasamy, Z Yu, RN Reger, ... The Journal of clinical investigation 121 (12), 4746-4757, 2011 | 388 | 2011 |
Mitochondrial membrane potential identifies cells with enhanced stemness for cellular therapy M Sukumar, J Liu, GU Mehta, SJ Patel, R Roychoudhuri, JG Crompton, ... Cell metabolism 23 (1), 63-76, 2016 | 384 | 2016 |
Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics JG Crompton, M Sukumar, R Roychoudhuri, D Clever, A Gros, RL Eil, ... Cancer research 75 (2), 296-305, 2015 | 381 | 2015 |
Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells C Wrzesinski, CM Paulos, A Kaiser, P Muranski, DC Palmer, L Gattinoni, ... Journal of immunotherapy 33 (1), 1-7, 2010 | 346 | 2010 |
Determinants of Successful CD8+ T-Cell Adoptive Immunotherapy for Large Established Tumors in Mice CA Klebanoff, L Gattinoni, DC Palmer, P Muranski, Y Ji, CS Hinrichs, ... Clinical Cancer Research 17 (16), 5343-5352, 2011 | 341 | 2011 |
Pembrolizumab treatment for progressive multifocal leukoencephalopathy I Cortese, P Muranski, Y Enose-Akahata, SK Ha, B Smith, MC Monaco, ... New England Journal of Medicine 380 (17), 1597-1605, 2019 | 333 | 2019 |
Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts SP Kerkar, P Muranski, A Kaiser, A Boni, L Sanchez-Perez, Z Yu, ... Cancer research 70 (17), 6725-6734, 2010 | 302 | 2010 |