| Somatic mutant clones colonize the human esophagus with age I Martincorena, JC Fowler, A Wabik, ARJ Lawson, F Abascal, MWJ Hall, ... Science 362 (6417), 911-917, 2018 | 946 | 2018 |
| Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas T Forshew, RG Tatevossian, ARJ Lawson, J Ma, G Neale, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 311 | 2009 |
| Somatic mutation landscapes at single-molecule resolution F Abascal, LMR Harvey, E Mitchell, ARJ Lawson, SV Lensing, P Ellis, ... Nature 593 (7859), 405-410, 2021 | 299 | 2021 |
| Somatic mutation rates scale with lifespan across mammals A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ... Nature 604 (7906), 517-524, 2022 | 260 | 2022 |
| Extensive heterogeneity in somatic mutation and selection in the human bladder ARJ Lawson, F Abascal, THH Coorens, Y Hooks, L O’Neill, C Latimer, ... Science 370 (6512), 75-82, 2020 | 216 | 2020 |
| Osimertinib benefit inEGFR-mutant NSCLC patients withT790M-mutation detected by circulating tumour DNA J Remon, C Caramella, C Jovelet, L Lacroix, A Lawson, S Smalley, ... Annals of Oncology 28 (4), 784-790, 2017 | 182 | 2017 |
| Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA D Gale, ARJ Lawson, K Howarth, M Madi, B Durham, S Smalley, ... PloS one 13 (3), e0194630, 2018 | 150 | 2018 |
| Patterns of within-host genetic diversity in SARS-CoV-2 G Tonkin-Hill, I Martincorena, R Amato, ARJ Lawson, M Gerstung, ... elife 10, e66857, 2021 | 133 | 2021 |
| MAPK pathway activation and the origins of pediatric low‐grade astrocytomas RG Tatevossian, ARJ Lawson, T Forshew, GFL Hindley, DW Ellison, ... Journal of cellular physiology 222 (3), 509-514, 2010 | 113 | 2010 |
| Increased somatic mutation burdens in normal human cells due to defective DNA polymerases PS Robinson, THH Coorens, C Palles, E Mitchell, F Abascal, S Olafsson, ... Nature genetics 53 (10), 1434-1442, 2021 | 109 | 2021 |
| Extensive phylogenies of human development inferred from somatic mutations THH Coorens, L Moore, PS Robinson, R Sanghvi, J Christopher, ... Nature 597 (7876), 387-392, 2021 | 98 | 2021 |
| Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing P Ellis, L Moore, MA Sanders, TM Butler, SF Brunner, H Lee-Six, ... Nature Protocols 16 (2), 841-871, 2021 | 89 | 2021 |
| MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas RG Tatevossian, B Tang, J Dalton, T Forshew, AR Lawson, J Ma, G Neale, ... Acta neuropathologica 120, 731-743, 2010 | 88 | 2010 |
| RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology ARJ Lawson, GFL Hindley, T Forshew, RG Tatevossian, GA Jamie, ... Genome research 21 (4), 505-514, 2011 | 76 | 2011 |
| RAF gene fusions are specific to pilocytic astrocytoma in a broad paediatric brain tumour cohort ARJ Lawson, RG Tatevossian, KP Phipps, SR Picker, A Michalski, ... Acta Neuropathologica 120, 271-273, 2010 | 65 | 2010 |
| Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer R Li, JR Ferdinand, KW Loudon, GS Bowyer, S Laidlaw, F Muyas, ... Cancer Cell 40 (12), 1583-1599. e10, 2022 | 51 | 2022 |
| Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways TA Jones, JN Jeyapalan, T Forshew, RG Tatevossian, ARJ Lawson, ... Acta neuropathologica communications 3, 1-13, 2015 | 45 | 2015 |
| Analytical performance and validation of an enhanced TAm-Seq circulating tumor DNA sequencing assay D Gale, V Plagnol, A Lawson, M Pugh, S Smalley, K Howarth, M Madi, ... Cancer Research 76 (14_Supplement), 3639-3639, 2016 | 25 | 2016 |
| Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight CD Hurst, G Cheng, FM Platt, MAA Castro, SM Nour-Al-Dain, P Eriksson, ... Cell Reports Medicine 2 (12), 2021 | 22 | 2021 |
| High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells M Boettcher, A Lawson, V Ladenburger, J Fredebohm, J Wolf, ... BMC genomics 15, 1-11, 2014 | 22 | 2014 |
