Albert Morales
Albert Morales
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Mitochondrial glutathione, a key survival antioxidant
M Marí, A Morales, A Colell, C García-Ruiz, JC Fernández-Checa
Antioxidants & redox signaling 11 (11), 2685-2700, 2009
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species: role of mitochondrial glutathione
C García-Ruiz, A Colell, M Marí, A Morales, JC Fernández-Checa
Journal of Biological Chemistry 272 (17), 11369-11377, 1997
Mitochondrial free cholesterol loading sensitizes to TNF-and Fas-mediated steatohepatitis
M Marí, F Caballero, A Colell, A Morales, J Caballeria, A Fernandez, ...
Cell metabolism 4 (3), 185-198, 2006
GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect
JC Fernandez-Checa, N Kaplowitz, C Garcia-Ruiz, A Colell, M Miranda, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 273 (1 …, 1997
Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of …
C García-Ruiz, A Colell, A Morales, N Kaplowitz, JC Fernández-Checa
Molecular pharmacology 48 (5), 825-834, 1995
Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor
A Colell, C García-Ruiz, M Miranda, E Ardite, M Marí, A Morales, ...
Gastroenterology 115 (6), 1541-1551, 1998
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione
F Caballero, A Fernández, N Matías, L Martínez, R Fucho, M Elena, ...
Journal of Biological Chemistry 285 (24), 18528-18536, 2010
Sphingolipids and cell death
A Morales, H Lee, FM Goñi, R Kolesnick, JC Fernandez-Checa
Apoptosis 12, 923-939, 2007
Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice
C García-Ruiz, A Colell, M Marí, A Morales, M Calvo, C Enrich, ...
The Journal of clinical investigation 111 (2), 197-208, 2003
Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma
J Montero, A Morales, L Llacuna, JM Lluis, O Terrones, G Basanez, ...
Cancer research 68 (13), 5246-5256, 2008
Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-κB via c-SRC–and oxidant-dependent cell death
JM Lluis, F Buricchi, P Chiarugi, A Morales, JC Fernandez-Checa
Cancer research 67 (15), 7368-7377, 2007
Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes.
C Garcia-Ruiz, A Morales, A Ballesta, J Rodes, N Kaplowitz, ...
The Journal of clinical investigation 94 (1), 193-201, 1994
Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes
C García-Ruiz, A Morales, A Colell, A Ballesta, J Rodés, N Kaplowitz, ...
Hepatology 21 (1), 207-214, 1995
Oxidative stress: role of mitochondria and protection by glutathione
JC Fernandez‐Checa, C García‐Ruiz, A Colell, A Morales, M Mari, ...
Biofactors 8 (1-2), 7-11, 1998
Mitochondrial glutathione: features, regulation and role in disease
M Marí, A Morales, A Colell, C García-Ruiz, N Kaplowitz, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (5), 3317-3328, 2013
Redox control of liver function in health and disease
M Mari, A Colell, A Morales, C von Montfort, C Garcia-Ruiz, ...
Antioxidants & redox signaling 12 (11), 1295-1331, 2010
Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: Effect of membrane physical properties andS-adenosyl-L-methionine
A Colell, C Garcia-Ruiz, A Morales, A Ballesta, M Ookhtens, J Rodes, ...
Hepatology 26 (3), 699-708, 1997
Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-α
C Garcıa-Ruiz, A Colell, A Morales, M Calvo, C Enrich, ...
Journal of Biological Chemistry 277 (39), 36443-36448, 2002
Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis
N Tarrats, A Moles, A Morales, C García‐Ruiz, JC Fernández‐Checa, ...
Hepatology 54 (1), 319-327, 2011
Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of γ-glutamylcysteine synthetase
A Morales, C Garcı́a-Ruiz, M Miranda, M Marı́, A Colell, E Ardite, ...
Journal of Biological Chemistry 272 (48), 30371-30379, 1997
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