Mohamed Ismail
Mohamed Ismail
Prof. of organic Chemistry, Faculty of Science, Mansoura University, Egypt.
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Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge
EW White, F Tanious, MA Ismail, AP Reszka, S Neidle, DW Boykin, ...
Biophysical chemistry 126 (1-3), 140-153, 2007
New treatment option for second-stage African sleeping sickness: in vitro and in vivo efficacy of aza analogs of DB289
T Wenzler, DW Boykin, MA Ismail, JE Hall, RR Tidwell, R Brun
Antimicrobial agents and chemotherapy 53 (10), 4185-4192, 2009
Synthesis and antiprotozoal activity of aza-analogues of furamidine
MA Ismail, R Brun, JD Easterbrook, FA Tanious, WD Wilson, DW Boykin
Journal of medicinal chemistry 46 (22), 4761-4769, 2003
Accumulation and intracellular distribution of antitrypanosomal diamidine compounds DB75 and DB820 in African trypanosomes
AM Mathis, JL Holman, LM Sturk, MA Ismail, DW Boykin, RR Tidwell, ...
Antimicrobial Agents and Chemotherapy 50 (6), 2185-2191, 2006
Novel dicationic imidazo [1, 2-a] pyridines and 5, 6, 7, 8-tetrahydro-imidazo [1, 2-a] pyridines as antiprotozoal agents
MA Ismail, R Brun, T Wenzler, FA Tanious, WD Wilson, DW Boykin
Journal of medicinal chemistry 47 (14), 3658-3664, 2004
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
EMBO Molecular Medicine 10 (1), 22-31, 2018
Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents
MA Ismail, R Brun, T Wenzler, FA Tanious, WD Wilson, DW Boykin
Bioorganic & medicinal chemistry 12 (20), 5405-5413, 2004
Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo [1, 2-a] pyridines and 5, 6, 7, 8-tetrahydro-imidazo [1, 2-a] pyridines
MA Ismail, RK Arafa, T Wenzler, R Brun, FA Tanious, WD Wilson, ...
Bioorganic & medicinal chemistry 16 (2), 683-691, 2008
Synthesis, DNA affinity, and antiprotozoal activity of linear dications: terphenyl diamidines and analogues
MA Ismail, RK Arafa, R Brun, T Wenzler, Y Miao, WD Wilson, C Generaux, ...
Journal of medicinal chemistry 49 (17), 5324-5332, 2006
Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in trypanosomes
AM Mathis, AS Bridges, MA Ismail, A Kumar, I Francesconi, ...
Antimicrobial agents and chemotherapy 51 (8), 2801-2810, 2007
Adsorption of Cu (II), Cd (II), Hg (II), Pb (II) and Zn (II) from aqueous single metal solutions by guanyl-modified cellulose
MAH I.M. Kenawy, M.A.H. Hafez, M.A. Ismail
International Journal of Biological Macromolecules, 2017
Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents
MA Ismail, A Batista-Parra, Y Miao, WD Wilson, T Wenzler, R Brun, ...
Bioorganic & medicinal chemistry 13 (24), 6718-6726, 2005
Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif
M Munde, MA Ismail, R Arafa, P Peixoto, CJ Collar, Y Liu, L Hu, ...
Journal of the American Chemical Society 129 (44), 13732-13743, 2007
Out-of-shape DNA minor groove binders: induced fit interactions of heterocyclic dications with the DNA minor groove
Y Miao, MPH Lee, GN Parkinson, A Batista-Parra, MA Ismail, S Neidle, ...
Biochemistry 44 (45), 14701-14708, 2005
Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines
R Nhili, P Peixoto, S Depauw, S Flajollet, X Dezitter, MM Munde, ...
Nucleic acids research 41 (1), 125-138, 2013
Evaluation of 4-amidinophenyl-2, 2′-bithiophene and its aza-analogue as novel corrosion inhibitors for CS in acidic media: experimental and theoretical study
AS Fouda, MA Ismail, GY EL-ewady, AS Abousalem
Journal of Molecular Liquids 240, 372-388, 2017
Water-mediated binding of agents that target the DNA minor groove
Y Liu, A Kumar, S Depauw, R Nhili, MH David-Cordonnier, MP Lee, ...
Journal of the American Chemical Society 133 (26), 10171-10183, 2011
Progress in the chemistry of 4‐thiazolidinones
WS Hamama, MA Ismail, S Shaaban, HH Zoorob
Journal of Heterocyclic Chemistry 45 (4), 939-956, 2008
Biological, ultrastructural effect and subcellular localization of aromatic diamidines in Trypanosoma cruzi
DGJ Batista, MGO Pacheco, A Kumar, D Branowska, MA Ismail, L Hu, ...
Parasitology 137 (2), 251-259, 2010
DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site
M Munde, A Kumar, R Nhili, S Depauw, MH David-Cordonnier, MA Ismail, ...
Journal of molecular biology 402 (5), 847-864, 2010
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