Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16 J Lukas, D Parry, L Aagaard, DJ Mann, J Bartkova, M Strauss, G Peters, ... Nature 375 (6531), 503-506, 1995 | 1213 | 1995 |
Lack of cyclin D‐Cdk complexes in Rb‐negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product. D Parry, S Bates, DJ Mann, G Peters The EMBO journal 14 (3), 503-511, 1995 | 514 | 1995 |
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013 | 503 | 2013 |
Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa KA Brayton, AOT Lau, DR Herndon, L Hannick, LS Kappmeyer, SJ Berens, ... PLoS pathogens 3 (10), e148, 2007 | 461 | 2007 |
Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins C Swanton, DJ Mann, B Fleckenstein, F Neipel, G Peters, N Jones Nature 390 (6656), 184-187, 1997 | 428 | 1997 |
Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes MJ Gardner, R Bishop, T Shah, EP De Villiers, JM Carlton, N Hall, Q Ren, ... Science 309 (5731), 134-137, 2005 | 391 | 2005 |
Protein serine/threonine phosphatases; an expanding family PTW Cohen, ND Brewis, V Hughes, DJ Mann FEBS letters 268 (2), 355-359, 1990 | 314 | 1990 |
Protein myristoylation in health and disease MH Wright, WP Heal, DJ Mann, EW Tate Journal of chemical biology 3, 19-35, 2010 | 288 | 2010 |
The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability ES Child, DJ Mann Cell cycle 5 (12), 1313-1319, 2006 | 246 | 2006 |
Global profiling of co- and post-translationally N-myristoylated proteomes in human cells E Thinon, RA Serwa, M Broncel, JA Brannigan, U Brassat, MH Wright, ... Nature communications 5 (1), 4919, 2014 | 242 | 2014 |
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach MH Wright, B Clough, MD Rackham, K Rangachari, JA Brannigan, ... Nature chemistry 6 (2), 112-121, 2014 | 212 | 2014 |
H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression K Barnouin, ML Dubuisson, ES Child, SF de Mattos, J Glassford, ... Journal of Biological Chemistry 277 (16), 13761-13770, 2002 | 196 | 2002 |
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53 K Yamakoshi, A Takahashi, F Hirota, R Nakayama, N Ishimaru, Y Kubo, ... Journal of Cell Biology 186 (3), 393-407, 2009 | 184 | 2009 |
Modulation of p27Kip1 levels by the cyclin encoded by Kaposi's sarcoma‐associated herpesvirus DJ Mann, ES Child, C Swanton, H Laman, N Jones The EMBO journal, 1999 | 180 | 1999 |
Cellular senescence: its role in tumor suppression and aging N Ohtani, DJ Mann, E Hara Cancer science 100 (5), 792-797, 2009 | 139 | 2009 |
Theileria-transformed bovine leukocytes have cancer hallmarks K Tretina, HT Gotia, DJ Mann, JC Silva Trends in parasitology 31 (7), 306-314, 2015 | 124 | 2015 |
Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy PA Summers, BW Lewis, J Gonzalez-Garcia, RM Porreca, AHM Lim, ... Nature communications 12 (1), 162, 2021 | 119 | 2021 |
E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest DJ Mann, NC Jones Current Biology 6 (4), 474-483, 1996 | 110 | 1996 |
A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin K Suntharalingam, O Mendoza, AA Duarte, DJ Mann, R Vilar Metallomics 5 (5), 514-523, 2013 | 109 | 2013 |
A Tri‐copper (II) Complex Displaying DNA‐Cleaving Properties and Antiproliferative Activity against Cancer Cells K Suntharalingam, DJ Hunt, AA Duarte, AJP White, DJ Mann, R Vilar Chemistry–A European Journal 18 (47), 15133-15141, 2012 | 98 | 2012 |