| LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 S Hacein-Bey-Abina, C Von Kalle, M Schmidt, MP McCormack, ... Science 302 (5644), 415-419, 2003 | 4506 | 2003 |
| Active genes dynamically colocalize to shared sites of ongoing transcription CS Osborne, L Chakalova, KE Brown, D Carter, A Horton, E Debrand, ... Nature genetics 36 (10), 1065-1071, 2004 | 1277 | 2004 |
| Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C B Mifsud, F Tavares-Cadete, AN Young, R Sugar, S Schoenfelder, ... Nature genetics 47 (6), 598-606, 2015 | 1058 | 2015 |
| Long-range chromatin regulatory interactions in vivo D Carter, L Chakalova, CS Osborne, Y Dai, P Fraser Nature genetics 32 (4), 623-626, 2002 | 824 | 2002 |
| Myc Dynamically and Preferentially Relocates to a Transcription Factory Occupied by Igh CS Osborne, L Chakalova, JA Mitchell, A Horton, AL Wood, DJ Bolland, ... PLoS biology 5 (8), e192, 2007 | 491 | 2007 |
| The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements S Schoenfelder, M Furlan-Magaril, B Mifsud, F Tavares-Cadete, R Sugar, ... Genome research 25 (4), 582-597, 2015 | 475 | 2015 |
| CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data J Cairns, P Freire-Pritchett, SW Wingett, C Várnai, A Dimond, V Plagnol, ... Genome biology 17, 1-17, 2016 | 433 | 2016 |
| Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome S Schoenfelder, R Sugar, A Dimond, BM Javierre, H Armstrong, B Mifsud, ... Nature genetics 47 (10), 1179-1186, 2015 | 396 | 2015 |
| Replication and transcription: shaping the landscape of the genome L Chakalova, E Debrand, JA Mitchell, CS Osborne, P Fraser Nature Reviews Genetics 6 (9), 669-677, 2005 | 260 | 2005 |
| Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code D Pannell, CS Osborne, S Yao, T Sukonnik, P Pasceri, A Karaiskakis, ... The EMBO journal, 2000 | 202 | 2000 |
| Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells P Freire-Pritchett, S Schoenfelder, C Várnai, SW Wingett, J Cairns, ... Elife 6, e21926, 2017 | 161 | 2017 |
| Large scale loss of data in low-diversity illumina sequencing libraries can be recovered by deferred cluster calling F Krueger, SR Andrews, CS Osborne PloS one 6 (1), e16607, 2011 | 125 | 2011 |
| The Corfu δβ thalassemia deletion disrupts γ-globin gene silencing and reveals post-transcriptional regulation of HbF expression L Chakalova, CS Osborne, YF Dai, B Goyenechea, ... Blood 105 (5), 2154-2160, 2005 | 112 | 2005 |
| MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs CD Wood, H Veenstra, S Khasnis, A Gunnell, HM Webb, ... Elife 5, e18270, 2016 | 109 | 2016 |
| The oncogenic transcription factor RUNX1/ETO corrupts cell cycle regulation to drive leukemic transformation N Martinez-Soria, L McKenzie, J Draper, A Ptasinska, H Issa, S Potluri, ... Cancer Cell 34 (4), 626-642. e8, 2018 | 104 | 2018 |
| The pre‐B‐cell receptor induces silencing of VpreB and λ5 transcription MJ Parker, S Licence, L Erlandsson, GR Galler, L Chakalova, ... The EMBO journal 24 (22), 3895-3905, 2005 | 94 | 2005 |
| Molecular determinants of NOTCH4 transcription in vascular endothelium J Wu, F Iwata, JA Grass, CS Osborne, L Elnitski, P Fraser, O Ohneda, ... Molecular and cellular biology, 2005 | 93 | 2005 |
| Retrovirus silencer blocking by the cHS4 insulator is CTCF independent S Yao, CS Osborne, RR Bharadwaj, P Pasceri, T Sukonnik, D Pannell, ... Nucleic acids research 31 (18), 5317-5323, 2003 | 83 | 2003 |
| Generation of an improved luciferase reporter gene plasmid that employs a novel mechanism for high-copy replication AG Bert, J Burrows, CS Osborne, PN Cockerill Plasmid 44 (2), 173-182, 2000 | 80 | 2000 |
| Amelioration of retroviral vector silencing in locus control region β-globin-transgenic mice and transduced F9 embryonic cells CS Osborne, P Pasceri, R Singal, T Sukonnik, GD Ginder, J Ellis Journal of virology 73 (7), 5490-5496, 1999 | 74 | 1999 |
