| Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity BM Simoes, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ... Cell reports 12 (12), 1968-1977, 2015 | 188 | 2015 |
| Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells JI Barrasa, N Olmo, P Pérez-Ramos, A Santiago-Gómez, E Lecona, ... Apoptosis 16, 1054-1067, 2011 | 116 | 2011 |
| Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling R Eyre, DG Alférez, A Santiago-Gómez, K Spence, JC McConnell, C Hart, ... Nature communications 10 (1), 5016, 2019 | 115 | 2019 |
| P-cadherin signals through the laminin receptor α6β4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells AF Vieira, AS Ribeiro, MR Dionísio, B Sousa, AR Nobre, A Albergaria, ... Oncotarget 5 (3), 679, 2014 | 69 | 2014 |
| Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms E Lecona, N Olmo, J Turnay, A Santiago-Gómez, I López de Silanes, ... Biochemical Journal 409 (1), 311-320, 2008 | 51 | 2008 |
| 4F2hc-silencing impairs tumorigenicity of HeLa cells via modulation of galectin-3 and β-catenin signaling, and MMP-2 expression A Santiago-Gómez, JI Barrasa, N Olmo, E Lecona, H Burghardt, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (9), 2045-2056, 2013 | 49 | 2013 |
| Patient-derived mammosphere and xenograft tumour initiation correlates with progression to metastasis R Eyre, DG Alférez, K Spence, M Kamal, FL Shaw, BM Simões, ... Journal of mammary gland biology and neoplasia 21, 99-109, 2016 | 48 | 2016 |
| Acquired resistance of ER-positive breast cancer to endocrine treatment confers an adaptive sensitivity to TRAIL through posttranslational downregulation of c-FLIP L Piggott, A Silva, T Robinson, A Santiago-Gómez, BM Simões, M Becker, ... Clinical Cancer Research 24 (10), 2452-2463, 2018 | 42 | 2018 |
| Histone deacetylase inhibitors upregulate MMP11 gene expression through Sp1/Smad complexes in human colon adenocarcinoma cells JI Barrasa, N Olmo, A Santiago-Gómez, E Lecona, P Anglard, J Turnay, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (2), 570-581, 2012 | 31 | 2012 |
| Increased expression of interleukin-1 receptor characterizes anti-estrogen-resistant ALDH+ breast cancer stem cells A Sarmiento-Castro, E Caamaño-Gutiérrez, AH Sims, NJ Hull, MI James, ... Stem Cell Reports 15 (2), 307-316, 2020 | 30 | 2020 |
| Resistance to butyrate impairs bile acid-induced apoptosis in human colon adenocarcinoma cells via up-regulation of Bcl-2 and inactivation of Bax JI Barrasa, A Santiago-Gómez, N Olmo, MA Lizarbe, J Turnay Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (12), 2201-2209, 2012 | 30 | 2012 |
| Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer BM Simões, A Santiago-Gómez, C Chiodo, T Moreira, D Conole, S Lovell, ... Oncogene 39 (25), 4896-4908, 2020 | 27 | 2020 |
| PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer CRB Santiago-Gómez A, Kedward T, Simões BM, Dragoni I, NicAmhlaoibh R ... Cancer Letters, 2019 | 26 | 2019 |
| PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer CRB Santiago-Gomez A, Dragoni I, NicAmhlaoibh R, Trivier E, Sabin V, Simoes ... bioRxiv, 2019 | 26* | 2019 |
| Acquisition of resistance to butyrate induces resistance to luminal components and other types of stress in human colon adenocarcinoma cells N Olmo, J Turnay, E Lecona, M García-Díez, B Llorente, ... Toxicology in vitro 21 (2), 254-261, 2007 | 16 | 2007 |
| Structural characterization and unfolding mechanism of human 4F2hc ectodomain J Turnay, J Fort, N Olmo, A Santiago-Gómez, M Palacín, MA Lizarbe Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (5), 536-544, 2011 | 12 | 2011 |
| Structural and lipid-binding characterization of human annexin A13a reveals strong differences with its long A13b isoform S Fernández-Lizarbe, E Lecona, A Santiago-Gómez, N Olmo, MA Lizarbe, ... Biological Chemistry 398 (3), 359-371, 2017 | 7 | 2017 |
| A dormant sub-population expressing interleukin-1 receptor characterises anti-estrogen resistant ALDH+ breast cancer stem cells A Sarmiento-Castro, E Caamaño-Gutiérrez, AH Sims, MI James, ... BiorXiv, 821876, 2019 | 3 | 2019 |
| Sulforadex targets breast cancer stem-like cells in patient-derived cells and xenograft tumors BM Simões, D Alferez, R Eyre, K Spence, A Santiago-Gomez, I Tanaka, ... Cancer Research 75 (15_Supplement), 2319-2319, 2015 | 3 | 2015 |
| Ethnicity influences breast cancer stem cells' drug resistance M Kamal, EHO Nafie, S Elsers, S Alanwar, R Ibrahim, F Farag, M Mlees, ... Breast J 24, 701-703, 2018 | 1 | 2018 |
Bruno M. SimõesUniversity of ManchesterVerified email at ics.manchester.ac.uk
