| Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-124, 2012 | 5130 | 2012 |
| Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial SB Hanauer, BG Feagan, GR Lichtenstein, LF Mayer, S Schreiber, ... The Lancet 359 (9317), 1541-1549, 2002 | 5090 | 2002 |
| Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of … MS Silverberg, J Satsangi, T Ahmad, IDR Arnott, CN Bernstein, SR Brant, ... Canadian Journal of Gastroenterology and Hepatology 19, 5A-36A, 2005 | 3932 | 2005 |
| Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3522 | 2010 |
| Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ... Nature genetics 42 (12), 1118-1125, 2010 | 3131 | 2010 |
| Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 (7359), 214-219, 2011 | 2951 | 2011 |
| Adalimumab for maintenance of clinical response and remission in patients with Crohn’s disease: the CHARM trial JF Colombel, WJ Sandborn, P Rutgeerts, R Enns, SB Hanauer, ... Gastroenterology 132 (1), 52-65, 2007 | 2688 | 2007 |
| Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012 | 2532 | 2012 |
| A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 J Hampe, A Franke, P Rosenstiel, A Till, M Teuber, K Huse, M Albrecht, ... Nature genetics 39 (2), 207-211, 2007 | 2311 | 2007 |
| Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2299 | 2010 |
| Genome-wide association study reveals genetic risk underlying Parkinson's disease J Simon-Sanchez, C Schulte, JM Bras, M Sharma, JR Gibbs, D Berg, ... Nature genetics 41 (12), 1308-1312, 2009 | 2190 | 2009 |
| Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, ... Nature genetics 43 (4), 333-338, 2011 | 2188 | 2011 |
| Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2159 | 2011 |
| Structural variation of chromosomes in autism spectrum disorder CR Marshall, A Noor, JB Vincent, AC Lionel, L Feuk, J Skaug, M Shago, ... The American Journal of Human Genetics 82 (2), 477-488, 2008 | 2129 | 2008 |
| Transcriptome and genome sequencing uncovers functional variation in humans T Lappalainen, M Sammeth, MR Friedländer, PAC ‘t Hoen, J Monlong, ... Nature 501 (7468), 506-511, 2013 | 2040 | 2013 |
| Mucosal flora in inflammatory bowel disease A Swidsinski, A Ladhoff, A Pernthaler, S Swidsinski, V Loening–Baucke, ... Gastroenterology 122 (1), 44-54, 2002 | 1807 | 2002 |
| Selecting therapeutic targets in inflammatory bowel disease (STRIDE): determining therapeutic goals for treat-to-target L Peyrin-Biroulet, W Sandborn, BE Sands, W Reinisch, W Bemelman, ... Official journal of the American College of Gastroenterology| ACG 110 (9 …, 2015 | 1801 | 2015 |
| Large-scale association analysis identifies new risk loci for coronary artery disease CARDIoGRAMplusC4D Consortium, P Deloukas, S Kanoni, C Willenborg, ... Nature genetics 45 (1), 25-33, 2013 | 1728 | 2013 |
| Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246-252, 2011 | 1701 | 2011 |
| Tofacitinib as induction and maintenance therapy for ulcerative colitis WJ Sandborn, C Su, BE Sands, GR D’Haens, S Vermeire, S Schreiber, ... New England Journal of Medicine 376 (18), 1723-1736, 2017 | 1649 | 2017 |
