CRISPR-Cas9 knockin mice for genome editing and cancer modeling RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ... Cell 159 (2), 440-455, 2014 | 1522 | 2014 |
Treating metastatic cancer with nanotechnology A Schroeder, DA Heller, MM Winslow, JE Dahlman, GW Pratt, R Langer, ... Nature Reviews Cancer 12 (1), 39-50, 2012 | 1124 | 2012 |
Emerging frontiers in drug delivery MW Tibbitt, JE Dahlman, R Langer Journal of the American Chemical Society 138 (3), 704-717, 2016 | 746 | 2016 |
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight JE Dahlman, C Barnes, OF Khan, A Thiriot, S Jhunjunwala, TE Shaw, ... Nature nanotechnology 9 (8), 648-655, 2014 | 552 | 2014 |
Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure HB Sager, M Hulsmans, KJ Lavine, MB Moreira, T Heidt, G Courties, ... Circulation research 119 (7), 853-864, 2016 | 289 | 2016 |
Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease JE Dahlman, OO Abudayyeh, J Joung, JS Gootenberg, F Zhang, ... Nature biotechnology 33 (11), 1159-1161, 2015 | 242 | 2015 |
Small RNA combination therapy for lung cancer W Xue, JE Dahlman, T Tammela, OF Khan, S Sood, A Dave, W Cai, ... Proceedings of the National Academy of Sciences 111 (34), E3553-E3561, 2014 | 227 | 2014 |
Silencing or stimulation? siRNA delivery and the immune system KA Whitehead, JE Dahlman, RS Langer, DG Anderson Annu Rev Chem Biomol Eng 2 (1), 77-96, 2011 | 212 | 2011 |
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction HB Sager, P Dutta, JE Dahlman, M Hulsmans, G Courties, Y Sun, T Heidt, ... Science translational medicine 8 (342), 342ra80-342ra80, 2016 | 147 | 2016 |
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ... Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018 | 135 | 2018 |
Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics JE Dahlman, KJ Kauffman, Y Xing, TE Shaw, FF Mir, CC Dlott, R Langer, ... Proceedings of the National Academy of Sciences 114 (8), 2060-2065, 2017 | 132 | 2017 |
Genetic and hypoxic alterations of the micro RNA‐210‐ISCU 1/2 axis promote iron–sulfur deficiency and pulmonary hypertension K White, Y Lu, S Annis, AE Hale, BN Chau, JE Dahlman, C Hemann, ... EMBO molecular medicine 7 (6), 695-713, 2015 | 112 | 2015 |
Challenges in carrier‐mediated intracellular delivery: moving beyond endosomal barriers MP Stewart, A Lorenz, J Dahlman, G Sahay Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 8 (3 …, 2016 | 111 | 2016 |
Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature OF Khan, EW Zaia, S Jhunjhunwala, W Xue, W Cai, DS Yun, CM Barnes, ... Nano letters 15 (5), 3008-3016, 2015 | 106 | 2015 |
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ... Nature metabolism 1 (9), 912-926, 2019 | 93 | 2019 |
A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, ... Nano letters 18 (3), 2148-2157, 2018 | 90 | 2018 |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components J Dahlman, RJ Platt, DG Anderson, RS Langer, F Zhang US Patent App. 14/705,719, 2015 | 90 | 2015 |
Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling S Yun, M Budatha, JE Dahlman, BG Coon, RT Cameron, R Langer, ... Nature cell biology 18 (10), 1043-1053, 2016 | 81 | 2016 |
Conjugated lipomers and uses thereof JE Dahlman, AD Schroeder, DG Anderson, RS Langer, CG Levins US Patent 9,238,716, 2016 | 80 | 2016 |
Ionizable Amphiphilic Dendrimer‐Based Nanomaterials with Alkyl‐Chain‐Substituted Amines for Tunable siRNA Delivery to the Liver Endothelium In Vivo OF Khan, EW Zaia, H Yin, RL Bogorad, JM Pelet, MJ Webber, I Zhuang, ... Angewandte Chemie International Edition 53 (52), 14397-14401, 2014 | 70 | 2014 |