| Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding A Anandan, GL Evans, K Condic-Jurkic, ML O’Mara, CM John, NJ Phillips, ... Proceedings of the National Academy of Sciences 114 (9), 2218-2223, 2017 | 127 | 2017 |
| Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ... Biochemical Journal 411 (2), 351-360, 2008 | 86 | 2008 |
| Thermodynamics of the fragile X mental retardation protein RGG box interactions with G quartet forming RNA KJ Zanotti, PE Lackey, GL Evans, MR Mihailescu Biochemistry 45 (27), 8319-8330, 2006 | 76 | 2006 |
| Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens? V Mitsakos, RCJ Dobson, FG Pearce, SR Devenish, GL Evans, ... Bioorganic & medicinal chemistry letters 18 (2), 842-844, 2008 | 58 | 2008 |
| A lipid site shapes the agonist response of a pentameric ligand-gated ion channel CM Hénault, C Govaerts, R Spurny, M Brams, A Estrada-Mondragon, ... Nature chemical biology 15 (12), 1156-1164, 2019 | 49 | 2019 |
| Implications of Binding Mode and Active Site Flexibility for Inhibitor Potency against the Salicylate Synthase from Mycobacterium tuberculosis G Chi, A Manos-Turvey, PD O’Connor, JM Johnston, GL Evans, EN Baker, ... Biochemistry 51 (24), 4868-4879, 2012 | 45 | 2012 |
| The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition A Castell, FL Short, GL Evans, TVM Cookson, EMM Bulloch, DDA Joseph, ... Biochemistry 52 (10), 1776-1787, 2013 | 26 | 2013 |
| Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis TVM Cookson, A Castell, EMM Bulloch, GL Evans, FL Short, EN Baker, ... Biochemical Journal 461 (1), 87-98, 2014 | 25 | 2014 |
| Repurposing the chemical scaffold of the anti‐arthritic drug lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis GL Evans, SA Gamage, EMM Bulloch, EN Baker, WA Denny, JS Lott ChemBioChem 15 (6), 852-864, 2014 | 24 | 2014 |
| Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex G Bashiri, JM Johnston, GL Evans, EMM Bulloch, DC Goldstone, ... Acta Crystallographica Section D: Biological Crystallography 71 (11), 2297-2308, 2015 | 23 | 2015 |
| Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site M Brams, C Govaerts, K Kambara, KL Price, R Spurny, A Gharpure, ... Elife 9, e51511, 2020 | 20 | 2020 |
| Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the … TVM Cookson, GL Evans, A Castell, EN Baker, JS Lott, EJ Parker Biochemistry 54 (39), 6082-6092, 2015 | 18 | 2015 |
| A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis G Evans, L Schuldt, MDW Griffin, SRA Devenish, F Grant Pearce, ... Archives of biochemistry and biophysics 512 (2), 154-159, 2011 | 18 | 2011 |
| PDBe and PDBe‐KB: Providing high‐quality, up‐to‐date and integrated resources of macromolecular structures to support basic and applied research and education M Varadi, S Anyango, SD Appasamy, D Armstrong, M Bage, J Berrisford, ... Protein Science 31 (10), e4439, 2022 | 13 | 2022 |
| Anthranilate phosphoribosyltransferase: Binding determinants for 5′-phospho-alpha-d-ribosyl-1′-pyrophosphate (PRPP) and the implications for inhibitor design GL Evans, DP Furkert, N Abermil, P Kundu, KM de Lange, EJ Parker, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (2), 264-274, 2018 | 7 | 2018 |
| A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket AF Chai, EMM Bulloch, GL Evans, JS Lott, EN Baker, JM Johnston Acta Crystallographica Section D: Biological Crystallography 71 (4), 862-872, 2015 | 7 | 2015 |
| Conformational flexibility of EptA driven by an interdomain helix provides insights for enzyme–substrate recognition A Anandan, NW Dunstan, TM Ryan, HDT Mertens, KYL Lim, GL Evans, ... IUCrJ 8 (5), 732-746, 2021 | 6 | 2021 |
| The physiologic effects of synchronous external circulatory assistance in patients in cardiogenic shock. CT Cloutier, HS Soroff, F Giron, WC Birtwell, JV Messer, TJ Ryan, ... Surgical Forum 22, 187-188, 1971 | 6 | 1971 |
| The Molecular Recognition Of The Insecticide Sulfoxaflor By Nicotinic Receptors Is Based On Atomic Interactions Identical To Bee‐Harming Neonicotinoids C Ulens, Q Bisseling, M Brams, A Mehregan, G Evans, D Pasini, F Gruss The FASEB Journal 33 (S1), 813.6-813.6, 2019 | 3 | 2019 |
| Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups GL Evans, DP Furkert, N Abermil, P Kundu, KM de Lange, EJ Parker, ... Data in brief 15, 1019-1029, 2017 | 3 | 2017 |
Associate Professor J. Shaun LottSchool of Biological Sciences, University of AucklandVerified email at auckland.ac.nz
