| Coordination of Rho GTPase activities during cell protrusion M Machacek, L Hodgson, C Welch, H Elliott, O Pertz, P Nalbant, A Abell, ... Nature 461 (7260), 99-103, 2009 | 1155 | 2009 |
| Spatiotemporal dynamics of RhoA activity in migrating cells O Pertz, L Hodgson, RL Klemke, KM Hahn Nature 440 (7087), 1069-1072, 2006 | 1009 | 2006 |
| A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E‐cadherin homoassociation O Pertz, D Bozic, AW Koch, C Fauser, A Brancaccio, J Engel The EMBO journal, 1999 | 530 | 1999 |
| Vinculin modulation of paxillin–FAK interactions regulates ERK to control survival and motility MC Subauste, O Pertz, ED Adamson, CE Turner, S Junger, KM Hahn The Journal of cell biology 165 (3), 371-381, 2004 | 345 | 2004 |
| Spatio-temporal Rho GTPase signaling–where are we now? O Pertz Journal of cell science 123 (11), 1841-1850, 2010 | 311 | 2010 |
| A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space RD Fritz, M Letzelter, A Reimann, K Martin, L Fusco, L Ritsma, B Ponsioen, ... Science signaling 6 (285), rs12-rs12, 2013 | 258 | 2013 |
| GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases J Birkenfeld, P Nalbant, BP Bohl, O Pertz, KM Hahn, GM Bokoch Developmental cell 12 (5), 699-712, 2007 | 254 | 2007 |
| Frequency modulation of ERK activation dynamics rewires cell fate H Ryu, M Chung, M Dobrzyński, D Fey, Y Blum, SS Lee, M Peter, ... Molecular systems biology 11 (11), 838, 2015 | 226 | 2015 |
| Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism K Wong, O Pertz, K Hahn, H Bourne Proceedings of the National Academy of Sciences 103 (10), 3639-3644, 2006 | 220 | 2006 |
| Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions PM Müller, J Rademacher, RD Bagshaw, C Wortmann, C Barth, ... Nature cell biology 22 (4), 498-511, 2020 | 213 | 2020 |
| Homophilic adhesion by cadherins AW Koch, D Bozic, O Pertz, J Engel Current opinion in structural biology 9 (2), 275-281, 1999 | 194 | 1999 |
| Protein kinase A governs a RhoA–RhoGDI protrusion–retraction pacemaker in migrating cells E Tkachenko, M Sabouri-Ghomi, O Pertz, C Kim, E Gutierrez, M Machacek, ... Nature cell biology 13 (6), 660-667, 2011 | 188 | 2011 |
| Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC TM Kitzing, Y Wang, O Pertz, JW Copeland, R Grosse Oncogene 29 (16), 2441-2448, 2010 | 158 | 2010 |
| Designing biosensors for Rho family proteins—deciphering the dynamics of Rho family GTPase activation in living cells O Pertz, KM Hahn Journal of cell science 117 (8), 1313-1318, 2004 | 141 | 2004 |
| Calcium-dependent homoassociation of E-cadherin by NMR spectroscopy: changes in mobility, conformation and mapping of contact regions D Häussinger, T Ahrens, HJ Sass, O Pertz, J Engel, S Grzesiek Journal of molecular biology 324 (4), 823-839, 2002 | 141 | 2002 |
| Spatio-temporal co-ordination of RhoA, Rac1 and Cdc42 activation during prototypical edge protrusion and retraction dynamics K Martin, A Reimann, RD Fritz, H Ryu, NL Jeon, O Pertz Scientific reports 6 (1), 21901, 2016 | 137 | 2016 |
| RhoA/ROCK-mediated switching between Cdc42-and Rac1-dependent protrusion in MTLn3 carcinoma cells M El-Sibai, O Pertz, H Pang, SC Yip, M Lorenz, M Symons, JS Condeelis, ... Experimental cell research 314 (7), 1540-1552, 2008 | 124 | 2008 |
| Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival PA Gagliardi, M Dobrzyński, MA Jacques, C Dessauges, P Ender, Y Blum, ... Developmental cell 56 (12), 1712-1726. e6, 2021 | 118 | 2021 |
| Two distinct filopodia populations at the growth cone allow to sense nanotopographical extracellular matrix cues to guide neurite outgrowth KJ Jang, MS Kim, D Feltrin, NL Jeon, KY Suh, O Pertz PloS one 5 (12), e15966, 2010 | 112 | 2010 |
| SrGAP2-dependent integration of membrane geometry and slit-robo-repulsive cues regulates fibroblast contact inhibition of locomotion RD Fritz, D Menshykau, K Martin, A Reimann, V Pontelli, O Pertz Developmental cell 35 (1), 78-92, 2015 | 92 | 2015 |
Klaus M HahnProfessor of Pharmacology, University of North Carolina Chapel HillVerified email at med.unc.edu
