PD-1 blockade in tumors with mismatch-repair deficiency DT Le, JN Uram, H Wang, BR Bartlett, H Kemberling, AD Eyring, ... New England Journal of Medicine 372 (26), 2509-2520, 2015 | 8819 | 2015 |
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ... Science 357 (6349), 409-413, 2017 | 5501 | 2017 |
Detection of circulating tumor DNA in early-and late-stage human malignancies C Bettegowda, M Sausen, RJ Leary, I Kinde, Y Wang, N Agrawal, ... Science translational medicine 6 (224), 224ra24-224ra24, 2014 | 4344 | 2014 |
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers H Li, KB Chiappinelli, AA Guzzetta, H Easwaran, RWC Yen, R Vatapalli, ... Oncotarget 5 (3), 587, 2014 | 412 | 2014 |
Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity NS Azad, EM Posadas, VE Kwitkowski, SM Steinberg, L Jain, ... Journal of clinical oncology: official journal of the American Society of …, 2008 | 373 | 2008 |
PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers M Yarchoan, LA Albacker, AC Hopkins, M Montesion, K Murugesan, ... JCI insight 4 (6), 2019 | 372 | 2019 |
The future of epigenetic therapy in solid tumours—lessons from the past N Azad, CA Zahnow, CM Rudin, SB Baylin Nature reviews Clinical oncology 10 (5), 256-266, 2013 | 368 | 2013 |
Phase I/Ib Study of Olaparib and Carboplatin in BRCA1 or BRCA2 Mutation-Associated Breast or Ovarian Cancer With Biomarker Analyses JM Lee, JL Hays, CM Annunziata, AM Noonan, L Minasian, JA Zujewski, ... Journal of the National Cancer Institute 106 (6), dju089, 2014 | 210 | 2014 |
Significance and implications of FDA approval of pembrolizumab for biomarker-defined disease MM Boyiadzis, JM Kirkwood, JL Marshall, CC Pritchard, NS Azad, ... Journal for immunotherapy of cancer 6 (1), 1-7, 2018 | 207 | 2018 |
Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases G Karagkounis, MS Torbenson, HD Daniel, NS Azad, LA Diaz Jr, ... Cancer 119 (23), 4137-4144, 2013 | 193 | 2013 |
Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: a phase 1 study MA Lowery, HA Burris, F Janku, RT Shroff, JM Cleary, NS Azad, L Goyal, ... The lancet Gastroenterology & hepatology 4 (9), 711-720, 2019 | 181 | 2019 |
Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors E Sausville, P LoRusso, M Carducci, J Carter, MF Quinn, L Malburg, ... Cancer chemotherapy and pharmacology 73, 539-549, 2014 | 177 | 2014 |
Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): A multicentre, open-label, phase 2a, multiple basket study M Javle, MJ Borad, NS Azad, R Kurzrock, GK Abou-Alfa, B George, ... The Lancet Oncology 22 (9), 1290-1300, 2021 | 173 | 2021 |
Programmed cell death ligand-1 (PD-L1) and CD8 expression profiling identify an immunologic subtype of pancreatic ductal adenocarcinomas with favorable survival L Danilova, WJ Ho, Q Zhu, T Vithayathil, A De Jesus-Acosta, NS Azad, ... Cancer immunology research 7 (6), 886-895, 2019 | 164 | 2019 |
Hand-foot skin reaction increases with cumulative sorafenib dose and with combination anti-vascular endothelial growth factor therapy NS Azad, JB Aragon-Ching, WL Dahut, M Gutierrez, WD Figg, L Jain, ... Clinical Cancer Research 15 (4), 1411-1416, 2009 | 164 | 2009 |
Current and emerging therapies for patients with advanced pancreatic ductal adenocarcinoma: a bright future ES Christenson, E Jaffee, NS Azad The Lancet Oncology 21 (3), e135-e145, 2020 | 160 | 2020 |
An analysis of genetic heterogeneity in untreated cancers JG Reiter, M Baretti, JM Gerold, AP Makohon-Moore, A Daud, ... Nature Reviews Cancer 19 (11), 639-650, 2019 | 157 | 2019 |
Single-center phase II trial of transarterial chemoembolization with drug-eluting beads for patients with unresectable hepatocellular carcinoma: initial experience in the … DK Reyes, JA Vossen, IR Kamel, NS Azad, TA Wahlin, MS Torbenson, ... Cancer journal (Sudbury, Mass.) 15 (6), 526, 2009 | 156 | 2009 |
Colorectal cancer in the young: epidemiology, prevention, management RL Siegel, CD Jakubowski, SA Fedewa, A Davis, NS Azad American Society of Clinical Oncology Educational Book 40, e75-e88, 2020 | 154 | 2020 |
Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours D Mahalingam, G Wilding, S Denmeade, J Sarantopoulas, D Cosgrove, ... British journal of cancer 114 (9), 986-994, 2016 | 152 | 2016 |