متابعة
Yu-Chiang Lai
Yu-Chiang Lai
بريد إلكتروني تم التحقق منه على bham.ac.uk
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise
J Jensen, PI Rustad, AJ Kolnes, YC Lai
Frontiers in physiology 2, 112, 2011
5082011
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ...
Cell reports 28 (7), 1717-1728. e6, 2019
3062019
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1
YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ...
The EMBO journal 34 (22), 2840-2861, 2015
1852015
Insulin action and signalling in fat and muscle from dexamethasone-treated rats
J Burén, YC Lai, M Lundgren, JW Eriksson, J Jensen
Archives of biochemistry and biophysics 474 (1), 91-101, 2008
1592008
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
M Johanns, YC Lai, MF Hsu, R Jacobs, D Vertommen, J Van Sande, ...
Nature communications 7 (1), 10856, 2016
1472016
Regulation of muscle glycogen synthase phosphorylation and kinetic properties by insulin, exercise, adrenaline and role in insulin resistance
J Jensen, YC Lai
Archives of physiology and biochemistry 115 (1), 13-21, 2009
1332009
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner
AP Seabright, NHF Fine, JP Barlow, SO Lord, I Musa, A Gray, JA Bryant, ...
The FASEB Journal 34 (5), 6284, 2020
1122020
Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation
KC Pao, M Stanley, C Han, YC Lai, P Murphy, K Balk, NT Wood, O Corti, ...
Nature chemical biology 12 (5), 324-331, 2016
1032016
A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK …
YC Lai, S Kviklyte, D Vertommen, L Lantier, M Foretz, B Viollet, S Hallén, ...
Biochemical Journal 460 (3), 363-375, 2014
902014
Kinetin riboside and its ProTides activate the Parkinson’s disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization
L Osgerby, YC Lai, PJ Thornton, J Amalfitano, CS Le Duff, I Jabeen, ...
Journal of medicinal chemistry 60 (8), 3518-3524, 2017
842017
GSK-3β regulation in skeletal muscles by adrenaline and insulin: evidence that PKA and PKB regulate different pools of GSK-3
J Jensen, EO Brennesvik, YC Lai, PR Shepherd
Cellular signalling 19 (1), 204-210, 2007
752007
Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle
Y Liu, YC Lai, EV Hill, D Tyteca, S Carpentier, A Ingvaldsen, ...
Biochemical Journal 455 (2), 195-206, 2013
742013
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release
D Nasteska, NHF Fine, FB Ashford, F Cuozzo, K Viloria, G Smith, A Dahir, ...
Nature communications 12 (1), 674, 2021
662021
Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle
L Bultot, TE Jensen, YC Lai, ALB Madsen, C Collodet, S Kviklyte, M Deak, ...
American Journal of Physiology-Endocrinology and Metabolism 311 (4), E706-E719, 2016
652016
Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents
YC Lai, E Zarrinpashneh, J Jensen
Journal of applied physiology 108 (5), 1106-1115, 2010
632010
Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle
Y Liu, D Vertommen, MH Rider, YC Lai
Cellular signalling 25 (9), 1877-1886, 2013
602013
A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle
YC Lai, Y Liu, R Jacobs, MH Rider
Biochemical Journal 447 (1), 137-147, 2012
602012
Glycogen content and contraction regulate glycogen synthase phosphorylation and affinity for UDP-glucose in rat skeletal muscles
YC Lai, JT Stuenæs, CH Kuo, J Jensen
American Journal of Physiology-Endocrinology and Metabolism 293 (6), E1622-E1629, 2007
602007
Effects of adrenaline on whole-body glucose metabolism and insulin-mediated regulation of glycogen synthase and PKB phosphorylation in human skeletal muscle
J Jensen, T Ruge, YC Lai, MK Svensson, JW Eriksson
Metabolism 60 (2), 215-226, 2011
502011
Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle
C Plaideau, YC Lai, S Kviklyte, N Zanou, L Löfgren, H Andersén, ...
Chemistry & biology 21 (11), 1497-1510, 2014
472014
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مقالات 1–20