Giovanni Gadda
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Same substrate, many reactions: oxygen activation in flavoenzymes
E Romero, JR Gómez Castellanos, G Gadda, MW Fraaije, A Mattevi
Chemical reviews 118 (4), 1742-1769, 2018
On the catalytic mechanism of choline oxidase
Fan, G Gadda
Journal of the American Chemical Society 127 (7), 2067-2074, 2005
Oxygen activation in flavoprotein oxidases: the importance of being positive
G Gadda
Biochemistry 51 (13), 2662-2669, 2012
Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments
S Tang, HC Wong, ZM Wang, Y Huang, J Zou, Y Zhuo, A Pennati, ...
Proceedings of the National Academy of Sciences 108 (39), 16265-16270, 2011
Role of Glu312 in Binding and Positioning of the Substrate for the Hydride Transfer Reaction in Choline Oxidase,
O Quaye, GT Lountos, Fan, AM Orville, G Gadda
Biochemistry 47 (1), 243-256, 2008
On the catalytic role of the conserved active site residue His466 of choline oxidase
M Ghanem, G Gadda
Biochemistry 44 (3), 893-904, 2005
Cloning, sequence analysis, and purification of choline oxidase from Arthrobacter globiformis: a bacterial enzyme involved in osmotic stress tolerance
F Fan, M Ghanem, G Gadda
Archives of biochemistry and biophysics 421 (1), 149-158, 2004
Characterization of Cholesterol Oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum
G Gadda, G Wels, L Pollegioni, S Zucchelli, D Ambrosius, MS Pilone, ...
European journal of biochemistry 250 (2), 369-376, 1997
Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases
G Gadda
Biochemistry 47 (52), 13745-13753, 2008
Cloning, Expression, and Purification of Choline Dehydrogenase from the Moderate Halophile Halomonas elongata
G Gadda, EE McAllister-Wilkins
Applied and environmental microbiology 69 (4), 2126-2132, 2003
The biochemistry of the metabolic poison propionate 3‐nitronate and its conjugate acid, 3‐nitropropionate
K Francis, C Smitherman, SF Nishino, JC Spain, G Gadda
IUBMB life 65 (9), 759-768, 2013
Nitronate monooxygenase, a model for anionic flavin semiquinone intermediates in oxidative catalysis
G Gadda, K Francis
Archives of biochemistry and biophysics 493 (1), 53-61, 2010
Crystallographic, Spectroscopic, and Computational Analysis of a Flavin C4a−Oxygen Adduct in Choline Oxidase,
AM Orville, GT Lountos, S Finnegan, G Gadda, R Prabhakar
Biochemistry 48 (4), 720-728, 2009
Spectroscopic and Kinetic Properties of Recombinant Choline Oxidase from Arthrobacter globiformis
M Ghanem, Fan, K Francis, G Gadda
Biochemistry 42 (51), 15179-15188, 2003
Kinetic mechanism of choline oxidase from Arthrobacter globiformis
G Gadda
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1646 (1-2), 112-118, 2003
The COMBREX project: design, methodology, and initial results
BP Anton, YC Chang, P Brown, HP Choi, LL Faller, J Guleria, Z Hu, ...
PLoS biology 11 (8), e1001638, 2013
Oxygen-and temperature-dependent kinetic isotope effects in choline oxidase: correlating reversible hydride transfer with environmentally enhanced tunneling
Fan, G Gadda
Journal of the American Chemical Society 127 (50), 17954-17961, 2005
Developing sensors for real-time measurement of high Ca2+ concentrations
J Zou, AM Hofer, MM Lurtz, G Gadda, AL Ellis, N Chen, Y Huang, ...
Biochemistry 46 (43), 12275-12288, 2007
Effects of reversing the protein positive charge in the proximity of the flavin N (1) locus of choline oxidase
M Ghanem, G Gadda
Biochemistry 45 (10), 3437-3447, 2006
Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3, 3-dimethylbutyraldehyde
Fan, MW Germann, G Gadda
Biochemistry 45 (6), 1979-1986, 2006
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