| Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell–and patient-derived tumor organoids L Huang, A Holtzinger, I Jagan, M BeGora, I Lohse, N Ngai, C Nostro, ... Nature medicine 21 (11), 1364-1371, 2015 | 716 | 2015 |
| Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4 X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ... Nature medicine 23 (9), 1063-1071, 2017 | 279 | 2017 |
| Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators L Huang, SK Muthuswamy Current opinion in genetics & development 20 (1), 41-50, 2010 | 156 | 2010 |
| Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly H Wang, S Lacoche, L Huang, B Xue, SK Muthuswamy Proceedings of the National Academy of Sciences 110 (1), 163-168, 2013 | 151 | 2013 |
| Discovery of a selective inhibitor of doublecortin like kinase 1 FM Ferguson, B Nabet, S Raghavan, Y Liu, AL Leggett, M Kuljanin, ... Nature chemical biology 16 (6), 635-643, 2020 | 92 | 2020 |
| Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors SC Chafe, FS Vizeacoumar, G Venkateswaran, O Nemirovsky, S Awrey, ... Science advances 7 (35), eabj0364, 2021 | 77 | 2021 |
| PDX-derived organoids model in vivo drug response and secrete biomarkers L Huang, B Bockorny, I Paul, D Akshinthala, PO Frappart, O Gandarilla, ... JCI insight 5 (21), 2020 | 76 | 2020 |
| Chick embryonic Schwann cells migrate anodally in small electrical fields MJ McKasson, L Huang, KR Robinson Experimental neurology 211 (2), 585-587, 2008 | 74 | 2008 |
| Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids L Huang, R Desai, DN Conrad, NC Leite, D Akshinthala, CM Lim, ... Cell Stem Cell 28 (6), 1090-1104. e6, 2021 | 73 | 2021 |
| Personalized RNA medicine for pancreatic cancer ME Gilles, L Hao, L Huang, R Rupaimoole, PP Lopez-Casas, E Pulver, ... Clinical Cancer Research 24 (7), 1734-1747, 2018 | 63 | 2018 |
| The involvement of Ca2+ and integrins in directional responses of zebrafish keratocytes to electric fields L Huang, P Cormie, MA Messerli, KR Robinson Journal of cellular physiology 219 (1), 162-172, 2009 | 58 | 2009 |
| Epidermal keratinocyte polarity and motility require Ca2+ influx through TRPV1 DM Graham, L Huang, KR Robinson, MA Messerli Journal of cell science 126 (20), 4602-4613, 2013 | 51 | 2013 |
| Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer JE Grossman, L Muthuswamy, L Huang, D Akshinthala, S Perea, ... Clinical Cancer Research, 2022 | 49 | 2022 |
| Discovery of new targets to control metastasis in pancreatic cancer by single-cell transcriptomics analysis of circulating tumor cells S Dimitrov-Markov, J Perales-Patón, B Bockorny, A Dopazo, M Muñoz, ... Molecular Cancer Therapeutics 19 (8), 1751-1760, 2020 | 34 | 2020 |
| Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids Q Meng, S Xie, GK Gray, MH Dezfulian, O Gandarilla, W Li, L Huang, ... Journal for immunotherapy of cancer 9 (11), 2021 | 31 | 2021 |
| Abnormal exocrine–endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8 S Kahraman, E Dirice, G Basile, D Diegisser, J Alam, BB Johansson, ... Nature Metabolism 4 (1), 76-89, 2022 | 26 | 2022 |
| Synthesis and Structure–Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold FM Ferguson, Y Liu, W Harshbarger, L Huang, J Wang, X Deng, ... Journal of medicinal chemistry 63 (14), 7817-7826, 2020 | 19 | 2020 |
| Reversing the direction of galvanotaxis with controlled increases in boundary layer viscosity BM Kobylkevich, A Sarkar, BR Carlberg, L Huang, S Ranjit, DM Graham, ... Physical biology 15 (3), 036005, 2018 | 16 | 2018 |
| A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer B Bockorny, L Muthuswamy, L Huang, M Hadisurya, CM Lim, LL Tsai, ... medRxiv, 2023 | 6 | 2023 |
| Personalized tumor vaccine for pancreatic cancer S Orr, L Huang, J Moser, D Stroopinsky, O Gandarilla, C DeCicco, ... Cancer Immunology, Immunotherapy 72 (2), 301-313, 2023 | 5 | 2023 |
