| Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 839 | 2015 |
| Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites S Kang, M Yang, Z Hong, L Zhang, Z Huang, X Chen, S He, Z Zhou, ... Acta Pharmaceutica Sinica B 10 (7), 1228-1238, 2020 | 647 | 2020 |
| Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions C Zhang, BR Griffith, Q Fu, C Albermann, X Fu, IK Lee, L Li, JS Thorson Science 313 (5791), 1291-1294, 2006 | 323 | 2006 |
| Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution GJ Williams, C Zhang, JS Thorson Nature chemical biology 3 (10), 657-662, 2007 | 311 | 2007 |
| Antibiotic optimization via in vitro glycorandomization X Fu, C Albermann, J Jiang, J Liao, C Zhang, JS Thorson Nature biotechnology 21 (12), 1467-1469, 2003 | 272 | 2003 |
| Antimalarial β-carboline and indolactam alkaloids from Marinactinospora thermotolerans, a deep sea isolate H Huang, Y Yao, Z He, T Yang, J Ma, X Tian, Y Li, C Huang, X Chen, W Li, ... Journal of natural products 74 (10), 2122-2127, 2011 | 184 | 2011 |
| Spiroindimicins A–D: New bisindole alkaloids from a deep-sea-derived actinomycete W Zhang, Z Liu, S Li, T Yang, Q Zhang, L Ma, X Tian, H Zhang, C Huang, ... Organic letters 14 (13), 3364-3367, 2012 | 159 | 2012 |
| Diversifying vancomycin via chemoenzymatic strategies X Fu, C Albermann, C Zhang, JS Thorson Organic Letters 7 (8), 1513-1515, 2005 | 135 | 2005 |
| Optimizing glycosyltransferase specificity via “hot spot” saturation mutagenesis presents a catalyst for novobiocin glycorandomization GJ Williams, RD Goff, C Zhang, JS Thorson Chemistry & biology 15 (4), 393-401, 2008 | 117 | 2008 |
| N–N-Coupled Indolosesquiterpene atropo-diastereomers from a marine-derived Actinomycete Q Zhang, A Mándi, S Li, Y Chen, W Zhang, X Tian, H Zhang, H Li, ... European Journal of Organic Chemistry 2012 (27), 5256-5262, 2012 | 115 | 2012 |
| Mechanistic insights into polycycle formation by reductive cyclization in ikarugamycin biosynthesis G Zhang, W Zhang, Q Zhang, T Shi, L Ma, Y Zhu, S Li, H Zhang, YL Zhao, ... Angewandte Chemie International Edition 53 (19), 4840-4844, 2014 | 106 | 2014 |
| Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase Y Xiao, S Li, S Niu, L Ma, G Zhang, H Zhang, G Zhang, J Ju, C Zhang Journal of the American Chemical Society 133 (4), 1092-1105, 2011 | 106 | 2011 |
| Pseudonocardians A–C, New Diazaanthraquinone Derivatives from a Deap-Sea Actinomycete Pseudonocardia sp. SCSIO 01299 S Li, X Tian, S Niu, W Zhang, Y Chen, H Zhang, X Yang, W Zhang, W Li, ... Marine drugs 9 (8), 1428-1439, 2011 | 104 | 2011 |
| Activation and characterization of a cryptic gene cluster reveals a cyclization cascade for polycyclic tetramate macrolactams S Saha, W Zhang, G Zhang, Y Zhu, Y Chen, W Liu, C Yuan, Q Zhang, ... Chemical Science 8 (2), 1607-1612, 2017 | 103 | 2017 |
| Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127 S Niu, S Li, Y Chen, X Tian, H Zhang, G Zhang, W Zhang, X Yang, ... The Journal of antibiotics 64 (11), 711-716, 2011 | 102 | 2011 |
| The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility C Zhang, C Albermann, X Fu, JS Thorson Journal of the American Chemical Society 128 (51), 16420-16421, 2006 | 97 | 2006 |
| Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses SA Borisova, C Zhang, H Takahashi, H Zhang, AW Wong, JS Thorson, ... Angewandte Chemie International Edition 45 (17), 2748-2753, 2006 | 96 | 2006 |
| Structural basis of transcription inhibition by fidaxomicin (lipiarmycin A3) W Lin, K Das, D Degen, A Mazumder, D Duchi, D Wang, YW Ebright, ... Molecular cell 70 (1), 60-71. e15, 2018 | 94 | 2018 |
| Identification and characterization of xiamycin A and oxiamycin gene cluster reveals an oxidative cyclization strategy tailoring indolosesquiterpene biosynthesis H Li, Q Zhang, S Li, Y Zhu, G Zhang, H Zhang, X Tian, S Zhang, J Ju, ... Journal of the American Chemical Society 134 (21), 8996-9005, 2012 | 92 | 2012 |
| Biosynthesis of himastatin: assembly line and characterization of three cytochrome P450 enzymes involved in the post-tailoring oxidative steps J Ma, Z Wang, H Huang, M Luo, D Zuo, B Wang, A Sun, YQ Cheng, ... Angewandte Chemie 123 (34), 7943-7948, 2011 | 92 | 2011 |
