Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers. M Ismail, S Botros, A Metwally, S William, A Farghally, LF Tao, TA Day, ... The American journal of tropical medicine and hygiene 60 (6), 932-935, 1999 | 542 | 1999 |
Synthesis and in vitro Evaluation of New Benzothiazole Derivatives as Schistosomicidal Agents MA Mahran, S William, F Ramzy, AM Sembel Molecules 12 (3), 622-633, 2007 | 122 | 2007 |
Praziquantel-induced tegumental damage in vitro is diminished in schistosomes derived from praziquantel-resistant infections TADAYJLB S. WILLIAM", S. BOTROS", M. ISMAIL#, A. FARGHALLY# parasitology, 2001 | 106 | 2001 |
Stability and reproductive fitness of Schistosoma mansoni isolates with decreased sensitivity to praziquantel S William, A Sabra, F Ramzy, M Mousa, Z Demerdash, JL Bennett, ... International journal for parasitology 31 (10), 1093-1100, 2001 | 86 | 2001 |
MCR synthesis of praziquantel derivatives AD Haixia Liu, Samia William, Eberhardt Herdtweck, Sanaa Botros Chemical biology & drug design 79 (4), 470-477, 2012 | 76 | 2012 |
Lack of evidence for an antischistosomal activity of myrrh in experimental animals S Botros, S William, F Ebeid, D Cioli, N Katz, TA Day, JL Bennett The American journal of tropical medicine and hygiene 71 (2), 206-210, 2004 | 75 | 2004 |
Effect of praziquantel on the immature stages of Schistosoma haematobium S Botros, L Pica-Mattoccia, S William, N El-Lakkani, D Cioli International journal for parasitology 35 (13), 1453-1457, 2005 | 62 | 2005 |
Activity of 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine against Schistosomiasis mansoni in Mice S Botros, S William, O Hammam, Z Zídek, A Holý Antimicrobial agents and chemotherapy 47 (12), 3853-3858, 2003 | 54 | 2003 |
Effect of the broad spectrum anthelmintic drug flubendazole upon Schistosoma mansoni experimentally infected mice NG Nessim, SI Hassan, S William, H El-Baz Arzneimittelforschung 50 (12), 1129-1133, 2000 | 37 | 2000 |
Validation of sensitivity to praziquantel using Schistosoma mansoni worm muscle tension and Ca2+-uptake as possible in vitro correlates to in vivo ED50 determination S William, S Botros International journal for parasitology 34 (8), 971-977, 2004 | 35 | 2004 |
Essential surgery: the way forward JA Henry, C Bem, C Grimes, E Borgstein, N Mkandawire, WEG Thomas, ... World journal of surgery 39, 822-832, 2015 | 34 | 2015 |
A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection A Radwan, NM El-Lakkany, S William, GS El-Feky, MY Al-Shorbagy, ... Parasites & vectors 12, 1-12, 2019 | 23 | 2019 |
Antischistosomal Activity of Hexadecyloxypropyl Cyclic 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine and Other Alkoxyalkyl Esters of Acyclic Nucleoside … SS Botros, S William, JR Beadle, N Valiaeva, KY Hostetler Antimicrobial agents and chemotherapy 53 (12), 5284-5287, 2009 | 18 | 2009 |
Effect of simultaneous and/or consecutive administration of the broad spectrum anthelmintic flubendazole together with praziquantel in experimental Schistosoma mansoni infection S William, F Guirguis, NG Nessim Arzneimittelforschung 53 (07), 532-537, 2003 | 16 | 2003 |
Further assessment of Mirazid as antischistosomal drug in experimental schistosomiasis hematobium F Ramzy, S Mahmoud, S William Pharmaceutical biology 48 (7), 775-779, 2010 | 15 | 2010 |
Neocryptolepine analogues containing N-substituted side-chains at C-11: synthesis and antischistosomicidal activity IE Sayed, F Ramzy, S William, ME Bahanasawy, MM Abd El-Sattar Medicinal Chemistry Research 21, 4219-4229, 2012 | 12 | 2012 |
Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity SS Botros, S William, ANA Sabra, NM El-Lakkany, SHS El-Din, ... International Journal for Parasitology: Drugs and Drug Resistance 9, 35-43, 2019 | 10 | 2019 |
The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo SS Botros, NM El-Lakkany, SHS El-Din, S William, AN Sabra, ... Experimental parasitology 208, 107793, 2020 | 6 | 2020 |
Testing two antimalarial drugs on Giardia lamblia in experimentally infected Hamsters S William, F Ramzy Re J Med Sci 41, 1-6, 2008 | 5 | 2008 |
Helminth genome analysis: the current status of the filarial and schistosome genome projects SA William, DA Johnston Parasitology 118, S19-38, 1999 | 4 | 1999 |