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Bosch Jürgen
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 12 (1), 1-222, 2016
13378*2016
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
2912016
The apicomplexan glideosome and adhesins – Structures and function
LE Boucher, J Bosch
Journal of Structural Biology, 2015
1212015
Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite
J Bosch, CA Buscaglia, B Krumm, BP Ingason, R Lucas, C Roach, ...
Proceedings of the National Academy of Sciences 104 (17), 7015-7020, 2007
1062007
Structure of the MTIP–MyoA complex, a key component of the malaria parasite invasion motor
J Bosch, S Turley, TM Daly, SM Bogh, ML Villasmil, C Roach, N Zhou, ...
Proceedings of the National Academy of Sciences 103 (13), 4852-4857, 2006
862006
Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase
J Bosch, MA Robien, C Mehlin, E Boni, A Riechers, FS Buckner, ...
Journal of medicinal chemistry 49 (20), 5939-5946, 2006
782006
The closed MTIP-myosin A-tail complex from the malaria parasite invasion machinery
J Bosch, S Turley, CM Roach, TM Daly, LW Bergman, WGJ Hol
Journal of molecular biology 372 (1), 77-88, 2007
672007
Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction
AUP Hain, RR Weltzer, H Hammond, B Jayabalasingham, RR Dinglasan, ...
Journal of structural biology 180 (3), 551-562, 2012
582012
Microfluidic assessment of red blood cell mediated microvascular occlusion
Y Man, E Kucukal, R An, QD Watson, J Bosch, PA Zimmerman, JA Little, ...
Lab on a Chip 20 (12), 2086-2099, 2020
562020
Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum …
JB AU Hain, D Bartee, NG Sanders, AS Miller,DJ Sullivan, J Levitskaya, CF Meyers
Journal of Medicinal Chemistry 57 (11), 4521–4531, 2014
542014
Crystal structure of glyceraldehyde‐3‐phosphate dehydrogenase from Plasmodium falciparum at 2.25 Å resolution reveals intriguing extra electron density in the active site
MA Robien, J Bosch, FS Buckner, WCE Van Voorhis, EA Worthey, P Myler, ...
Proteins: Structure, Function, and Bioinformatics 62 (3), 570-577, 2006
502006
Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin
RG Saraiva, CR Huitt-Roehl, A Tripathi, YQ Cheng, J Bosch, ...
Scientific reports 8 (1), 6176, 2018
462018
Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium
CLMJ Verlinde, E Fan, S Shibata, Z Zhang, Z Sun, W Deng, J Ross, J Kim, ...
Current topics in medicinal chemistry 9 (18), 1678-1687, 2009
442009
Autophagy in Plasmodium, a multifunctional pathway?
AUP Hain, J Bosch
Computational and structural biotechnology journal 8 (11), e201308002, 2013
422013
Structural genomics of pathogenic protozoa: an overview
E Fan, D Baker, S Fields, MH Gelb, FS Buckner, WC Van Voorhis, ...
Structural Proteomics: High-Throughput Methods, 497-513, 2008
412008
DXP Synthase‐Catalyzed C N Bond Formation: Nitroso Substrate Specificity Studies Guide Selective Inhibitor Design
F Morris, R Vierling, L Boucher, J Bosch, CL Freel Meyers
ChemBioChem 14 (11), 1309-1315, 2013
392013
Characterization of the ATG8-conjugation system in 2 Plasmodium species with special focus on the liver stage: possible linkage between the apicoplastic and autophagic systems?
B Jayabalasingham, C Voss, K Ehrenman, JD Romano, ME Smith, ...
Autophagy 10 (2), 269-284, 2014
362014
Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum
J Bosch, MH Paige, AB Vaidya, LW Bergman, WGJ Hol
Journal of structural biology 178 (1), 61-73, 2012
362012
Structure of a ribulose 5‐phosphate 3‐epimerase from Plasmodium falciparum
J Caruthers, J Bosch, F Buckner, W Van Voorhis, P Myler, E Worthey, ...
PROTEINS: Structure, Function, and Bioinformatics 62 (2), 338-342, 2006
332006
Guidelines for the use and interpretation of assays for monitoring autophagy 1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
322021
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