Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder D Demontis, RK Walters, J Martin, M Mattheisen, TD Als, E Agerbo, ... Nature genetics 51 (1), 63-75, 2019 | 2231 | 2019 |
Social supports and serotonin transporter gene moderate depression in maltreated children J Kaufman, BZ Yang, H Douglas-Palumberi, S Houshyar, D Lipschitz, ... Proceedings of the National Academy of Sciences 101 (49), 17316-17321, 2004 | 1167 | 2004 |
Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor J Duan, MS Wainwright, JM Comeron, N Saitou, AR Sanders, J Gelernter, ... Human molecular genetics 12 (3), 205-216, 2003 | 1153 | 2003 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1120 | 2019 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 931 | 2021 |
Brain-derived neurotrophic factor–5-HTTLPR gene interactions and environmental modifiers of depression in children J Kaufman, BZ Yang, H Douglas-Palumberi, D Grasso, D Lipschitz, ... Biological psychiatry 59 (8), 673-680, 2006 | 908 | 2006 |
A functional polymorphism of the μ-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients DW Oslin, W Berrettini, HR Kranzler, H Pettinati, J Gelernter, JR Volpicelli, ... Neuropsychopharmacology 28 (8), 1546-1552, 2003 | 732 | 2003 |
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders RK Walters, R Polimanti, EC Johnson, JN McClintick, MJ Adams, ... Nature neuroscience 21 (12), 1656-1669, 2018 | 631 | 2018 |
Human dopamine D1 receptor encoded by an intronless gene on chromosome 5 RK Sunahara, HB Niznik, DM Weiner, TM Stormann, MR Brann, ... Nature 347 (6288), 80-83, 1990 | 622 | 1990 |
Psychiatric genomics: an update and an agenda PF Sullivan, A Agrawal, CM Bulik, OA Andreassen, AD Børglum, G Breen, ... American Journal of Psychiatry 175 (1), 15-27, 2018 | 620 | 2018 |
Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African-and European-American and Japanese populations and in alcohol … J Gelernter, H Kranzler, JF Cubells Human genetics 101, 243-246, 1997 | 578 | 1997 |
DCDC2 is associated with reading disability and modulates neuronal development in the brain H Meng, SD Smith, K Hager, M Held, J Liu, RK Olson, BF Pennington, ... Proceedings of the National Academy of Sciences 102 (47), 17053-17058, 2005 | 567 | 2005 |
The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults DG Kilpatrick, KC Koenen, KJ Ruggiero, R Acierno, S Galea, HS Resnick, ... American Journal of Psychiatry 164 (11), 1693-1699, 2007 | 523 | 2007 |
International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci CM Nievergelt, AX Maihofer, T Klengel, EG Atkinson, CY Chen, KW Choi, ... Nature communications 10 (1), 4558, 2019 | 520 | 2019 |
Largest GWAS of PTSD (N= 20 070) yields genetic overlap with schizophrenia and sex differences in heritability LE Duncan, A Ratanatharathorn, AE Aiello, LM Almli, AB Amstadter, ... Molecular psychiatry 23 (3), 666-673, 2018 | 480 | 2018 |
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations HR Kranzler, H Zhou, RL Kember, R Vickers Smith, AC Justice, ... Nature communications 10 (1), 1499, 2019 | 468 | 2019 |
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability JA Pasman, KJH Verweij, Z Gerring, S Stringer, S Sanchez-Roige, ... Nature neuroscience 21 (9), 1161-1170, 2018 | 453 | 2018 |
A prospective cohort study investigating factors associated with depression during medical internship S Sen, HR Kranzler, JH Krystal, H Speller, G Chan, J Gelernter, C Guille Archives of general psychiatry 67 (6), 557-565, 2010 | 452 | 2010 |
Genome-wide association study of alcohol dependence: significant findings in African-and European-Americans including novel risk loci J Gelernter, HR Kranzler, R Sherva, L Almasy, R Koesterer, AH Smith, ... Molecular psychiatry 19 (1), 41-49, 2014 | 417 | 2014 |
Multiple independent loci at chromosome 15q25. 1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD NL Saccone, RC Culverhouse, TH Schwantes-An, DS Cannon, X Chen, ... PLoS genetics 6 (8), e1001053, 2010 | 406 | 2010 |