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Mahmoud F. Abo-Ashour
Mahmoud F. Abo-Ashour
Faculty of Pharmacy
Verified email at eru.edu.eg
Title
Cited by
Cited by
Year
Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene) thiazolidin-2-ylidene) amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and …
WM Eldehna, MF Abo-Ashour, A Nocentini, P Gratteri, IH Eissa, M Fares, ...
European journal of medicinal chemistry 139, 250-262, 2017
1252017
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC …
WM Eldehna, MF Abo-Ashour, A Nocentini, RS El-Haggar, S Bua, ...
European journal of medicinal chemistry 162, 147-160, 2019
902019
Novel indole-thiazolidinone conjugates: Design, synthesis and whole-cell phenotypic evaluation as a novel class of antimicrobial agents
MF Abo-Ashour, WM Eldehna, RF George, MM Abdel-Aziz, MM Elaasser, ...
European Journal of Medicinal Chemistry 160, 49-60, 2018
852018
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico …
MF Abo-Ashour, WM Eldehna, A Nocentini, A Bonardi, S Bua, HS Ibrahim, ...
European Journal of Medicinal Chemistry 184, 111768, 2019
722019
Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation
WM Eldehna, MF Abo-Ashour, HS Ibrahim, GH Al-Ansary, HA Ghabbour, ...
Journal of enzyme inhibition and medicinal chemistry 33 (1), 686-700, 2018
692018
Development of isatin-thiazolo [3, 2-a] benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and …
WM Eldehna, MA El Hassab, MF Abo-Ashour, T Al-Warhi, MM Elaasser, ...
Bioorganic Chemistry 110, 104748, 2021
632021
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX
WM Eldehna, MF Abo-Ashour, E Berrino, D Vullo, HA Ghabbour, ...
Bioorganic chemistry 83, 549-558, 2019
572019
Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies
MF Abo-Ashour, WM Eldehna, A Nocentini, HS Ibrahim, S Bua, ...
European Journal of Medicinal Chemistry 157, 28-36, 2018
552018
3-Methylthiazolo [3, 2-a] benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and …
AAM Alkhaldi, MM Al-Sanea, A Nocentini, WM Eldehna, ZM Elsayed, ...
European Journal of Medicinal Chemistry 207, 112745, 2020
532020
Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies
MF Abo-Ashour, WM Eldehna, A Nocentini, HS Ibrahim, S Bua, ...
Bioorganic Chemistry 87, 794-802, 2019
522019
Novel [(N-alkyl-3-indolylmethylene) hydrazono] oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in …
T Al-Warhi, MF Abo-Ashour, H Almahli, OJ Alotaibi, MM Al-Sanea, ...
Journal of enzyme inhibition and medicinal chemistry 35 (1), 1300-1309, 2020
512020
Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4, 5-dihydropyrazoles as anticancer agents with potential EGFR …
WM Eldehna, MA El Hassab, ZM Elsayed, T Al-Warhi, H Elkady, ...
Scientific reports 12 (1), 12821, 2022
392022
Identification of N-phenyl-2-(phenylsulfonyl) acetamides/propanamides as new SLC-0111 analogues: synthesis and evaluation of the carbonic anhydrase inhibitory activities
MM Elbadawi, WM Eldehna, A Nocentini, MF Abo-Ashour, EB Elkaeed, ...
European Journal of Medicinal Chemistry 218, 113360, 2021
252021
Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies
AH Eldeeb, MF Abo-Ashour, A Angeli, A Bonardi, DS Lasheen, ...
European Journal of Medicinal Chemistry 221, 113486, 2021
222021
Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active …
HA Allam, SH Fahim, MF Abo-Ashour, A Nocentini, ME Elbakry, ...
European Journal of Medicinal Chemistry 179, 547-556, 2019
222019
Synthesis and biological evaluation of 2-aminothiazole-thiazolidinone conjugates as potential antitubercular agents
MF Abo-Ashour, WM Eldehna, RF George, MM Abdel-Aziz, MM Elaasser, ...
Future medicinal chemistry 10 (12), 1405-1419, 2018
222018
Development of 2-oxindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells
WM Eldehna, MF Abo-Ashour, T Al-Warhi, ST Al-Rashood, A Alharbi, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 320-329, 2021
162021
Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment
MF Abo-Ashour, H Almahli, A Bonardi, A Khalil, T Al-Warhi, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2256-2264, 2022
82022
Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and …
MK Elgohary, SR Abd El Hadi, MF Abo-Ashour, ME Abo-El Fetoh, H Afify, ...
Bioorganic Chemistry 139, 106724, 2023
62023
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