| Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4 (3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers HA Mahdy, MK Ibrahim, AM Metwaly, A Belal, ABM Mehany, ... Bioorganic Chemistry 94, 103422, 2020 | 128 | 2020 |
| Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFR WT and EGFR T790M AA Nasser, IH Eissa, MR Oun, MA El-Zahabi, MS Taghour, A Belal, ... Organic & biomolecular chemistry 18 (38), 7608-7634, 2020 | 104 | 2020 |
| New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies H Elkady, A Elwan, HA El-Mahdy, AS Doghish, A Ismail, MS Taghour, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 403-416, 2022 | 102 | 2022 |
| Discovery of thieno [2, 3-d] pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents SA El-Metwally, MM Abou-El-Regal, IH Eissa, ABM Mehany, HA Mahdy, ... Bioorganic Chemistry 112, 104947, 2021 | 79 | 2021 |
| New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis NA Alsaif, MA Dahab, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ... Bioorganic Chemistry 110, 104807, 2021 | 74 | 2021 |
| Design, synthesis, and anti-proliferative evaluation of new quinazolin-4 (3H)-ones as potential VEGFR-2 inhibitors K El-Adl, AGA El-Helby, RR Ayyad, HA Mahdy, MM Khalifa, HA Elnagar, ... Bioorganic & Medicinal Chemistry 29, 115872, 2021 | 74 | 2021 |
| Design, molecular docking, in vitro, and in vivo studies of new quinazolin-4 (3H)-ones as VEGFR-2 inhibitors with potential activity against hepatocellular carcinoma IH Eissa, MK Ibrahim, AM Metwaly, A Belal, ABM Mehany, AA Abdelhady, ... Bioorganic Chemistry 107, 104532, 2021 | 71 | 2021 |
| Discovery of new quinazolin-4 (3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation IH Eissa, AGA El-Helby, HA Mahdy, MM Khalifa, HA Elnagar, ... Bioorganic Chemistry 105, 104380, 2020 | 69 | 2020 |
| New bis ([1, 2, 4] triazolo)[4, 3-a: 3′, 4′-c] quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer … MM Alanazi, HA Mahdy, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Bioorganic Chemistry 112, 104949, 2021 | 64 | 2021 |
| Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors IH Eissa, AM Metwaly, A Belal, ABM Mehany, RR Ayyad, K El‐Adl, ... Archiv der Pharmazie 352 (11), 1900123, 2019 | 62 | 2019 |
| Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II … AGA El-Helby, H Sakr, RR Ayyad, HA Mahdy, MM Khalifa, A Belal, ... Bioorganic chemistry 103, 104233, 2020 | 58 | 2020 |
| Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies MM Khalifa, AA Al-Karmalawy, EB Elkaeed, MS Nafie, MA Tantawy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 299-314, 2022 | 51 | 2022 |
| Design, synthesis, molecular docking, anticancer evaluations, and in silico pharmacokinetic studies of novel 5‐[(4‐chloro/2, 4‐dichloro) benzylidene] thiazolidine‐2, 4‐dione … K El‐Adl, AGA El‐Helby, H Sakr, RR Ayyad, HA Mahdy, M Nasser, ... Archiv der Pharmazie 354 (2), 2000279, 2021 | 47 | 2021 |
| New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies EB Elkaeed, MS Taghour, HA Mahdy, WM Eldehna, NM El-Deeb, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2191-2205, 2022 | 35 | 2022 |
| Modified benzoxazole-based VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, and anti-proliferative evaluation A Elwan, AE Abdallah, HA Mahdy, MA Dahab, MS Taghour, EB Elkaeed, ... Molecules 27 (15), 5047, 2022 | 28 | 2022 |
| Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation MS Taghour, HA Mahdy, MH Gomaa, A Aglan, MG Eldeib, A Elwan, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2063-2077, 2022 | 26 | 2022 |
| Screening of some sulfonamide and sulfonylurea derivatives as anti-Alzheimer’s agents targeting BACE1 and PPARγ N Li, Y Wang, W Li, H Li, L Yang, J Wang, HA Mahdy, ABM Mehany, ... Journal of Chemistry 2020, 1-19, 2020 | 24 | 2020 |
| Identification of new [1, 2, 4] triazolo [4, 3-a] quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, WA Alanazi, ... Bioorganic & Medicinal Chemistry 46, 116384, 2021 | 23 | 2021 |
| Design, synthesis, docking, and biological evaluation of some novel 5-chloro-2-substituted sulfanylbenzoxazole derivatives as anticonvulsant agents MK Ibrahim, K El-Adl, MF Zayed, HA Mahdy Medicinal Chemistry Research 24, 99-114, 2015 | 23 | 2015 |
| Discovery of 2, 4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms WM Eldehna, MS Taghour, T Al-Warhi, A Nocentini, MM Elbadawi, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 531-541, 2022 | 18 | 2022 |
Ibrahim H. EissaProfessor, Faculty of pharmacy, Al-Azhar UniversityVerified email at azhar.edu.eg
