متابعة
Alex Cagan
Alex Cagan
Wellcome Sanger Institute
بريد إلكتروني تم التحقق منه على sanger.ac.uk
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Somatic mutant clones colonize the human esophagus with age
I Martincorena, JC Fowler, A Wabik, ARJ Lawson, F Abascal, MWJ Hall, ...
Science 362 (6417), 911-917, 2018
9462018
Great ape genetic diversity and population history
J Prado-Martinez, PH Sudmant, JM Kidd, H Li, JL Kelley, ...
Nature 499 (7459), 471-475, 2013
9342013
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors
MD Young, TJ Mitchell, FA Vieira Braga, MGB Tran, BJ Stewart, ...
science 361 (6402), 594-599, 2018
5732018
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7
B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira, S Marelli, WT Harvey, ...
Cell reports 35 (13), 2021
4242021
Spatiotemporal immune zonation of the human kidney
BJ Stewart, JR Ferdinand, MD Young, TJ Mitchell, KW Loudon, AM Riding, ...
Science 365 (6460), 1461-1466, 2019
3182019
Evidence of long-term gene flow and selection during domestication from analyses of Eurasian wild and domestic pig genomes
LAF Frantz, JG Schraiber, O Madsen, HJ Megens, A Cagan, M Bosse, ...
Nature genetics 47 (10), 1141-1148, 2015
3022015
Somatic mutation landscapes at single-molecule resolution
F Abascal, LMR Harvey, E Mitchell, ARJ Lawson, SV Lensing, P Ellis, ...
Nature 593 (7859), 405-410, 2021
2992021
Somatic mutation rates scale with lifespan across mammals
A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ...
Nature 604 (7906), 517-524, 2022
2602022
Extensive heterogeneity in somatic mutation and selection in the human bladder
ARJ Lawson, F Abascal, THH Coorens, Y Hooks, L O’Neill, C Latimer, ...
Science 370 (6512), 75-82, 2020
2162020
The mutational landscape of human somatic and germline cells
L Moore, A Cagan, THH Coorens, MDC Neville, R Sanghvi, MA Sanders, ...
Nature 597 (7876), 381-386, 2021
2132021
Clonal dynamics of haematopoiesis across the human lifespan
E Mitchell, M Spencer Chapman, N Williams, KJ Dawson, N Mende, ...
Nature 606 (7913), 343-350, 2022
1932022
Embryonal precursors of Wilms tumor
THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ...
Science 366 (6470), 1247-1251, 2019
1272019
Extensive phylogenies of human development inferred from somatic mutations
THH Coorens, L Moore, PS Robinson, R Sanghvi, J Christopher, ...
Nature 597 (7876), 387-392, 2021
982021
Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing
P Ellis, L Moore, MA Sanders, TM Butler, SF Brunner, H Lee-Six, ...
Nature Protocols 16 (2), 841-871, 2021
892021
Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids
N Georgakopoulos, N Prior, B Angres, G Mastrogiovanni, A Cagan, ...
BMC developmental biology 20, 1-20, 2020
862020
Epidermal tissue adapts to restrain progenitors carrying clonal p53 mutations
K Murai, G Skrupskelyte, G Piedrafita, M Hall, V Kostiou, SH Ong, T Nagy, ...
Cell stem cell 23 (5), 687-699. e8, 2018
862018
Identification of genomic variants putatively targeted by selection during dog domestication
A Cagan, T Blass
BMC evolutionary biology 16, 1-13, 2016
782016
Genetic influences on brain gene expression in rats selected for tameness and aggression
HO Heyne, S Lautenschläger, R Nelson, F Besnier, M Rotival, A Cagan, ...
Genetics 198 (3), 1277-1290, 2014
732014
Evolution of the pygmy phenotype: Evidence of positive selection from genome-wide scans in African, Asian, and Melanesian pygmies
AB Migliano, IG Romero, M Metspalu, M Leavesley, L Pagani, T Antao, ...
Human biology 85 (1-3), 251-284, 2013
732013
Natural selection in the great apes
A Cagan, C Theunert, H Laayouni, G Santpere, M Pybus, F Casals, ...
Molecular biology and evolution 33 (12), 3268-3283, 2016
722016
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مقالات 1–20