Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer H Hurwitz, L Fehrenbacher, W Novotny, T Cartwright, J Hainsworth, ... New England journal of medicine 350 (23), 2335-2342, 2004 | 13376 | 2004 |
The biology of VEGF and its receptors N Ferrara, HP Gerber, J LeCouter Nature medicine 9 (6), 669-676, 2003 | 12545 | 2003 |
Vascular endothelial growth factor is a secreted angiogenic mitogen DW Leung, G Cachianes, WJ Kuang, DV Goeddel, N Ferrara | 6871 | 1989 |
The biology of vascular endothelial growth factor N Ferrara, T Davis-Smyth Endocrine reviews 18 (1), 4-25, 1997 | 6492 | 1997 |
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo KJ Kim, B Li, J Winer, M Armanini, N Gillett, HS Phillips, N Ferrara Nature 362 (6423), 841-844, 1993 | 5035 | 1993 |
Vascular endothelial growth factor: basic science and clinical progress N Ferrara Endocrine reviews 25 (4), 581-611, 2004 | 4970 | 2004 |
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders LP Aiello, RL Avery, PG Arrigg, BA Keyt, HD Jampel, ST Shah, ... New England Journal of Medicine 331 (22), 1480-1487, 1994 | 4946 | 1994 |
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene N Ferrara, K Carver-Moore, H Chen, M Dowd, L Lu, KS O'Shea, ... Nature 380 (6573), 439-442, 1996 | 4715 | 1996 |
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells N Ferrara, WJ Henzel Biochemical and biophysical research communications 161 (2), 851-858, 1989 | 4106 | 1989 |
Angiogenesis as a therapeutic target N Ferrara, RS Kerbel Nature 438 (7070), 967-974, 2005 | 3406 | 2005 |
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer N Ferrara, KJ Hillan, HP Gerber, W Novotny Nature reviews Drug discovery 3 (5), 391-400, 2004 | 3276 | 2004 |
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor C De Vries, JA Escobedo, H Ueno, K Houck, N Ferrara, LT Williams Science 255 (5047), 989-991, 1992 | 2833 | 1992 |
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway: requirement for Flk-1/KDR … HP Gerber, A McMurtrey, J Kowalski, M Yan, BA Keyt, V Dixit, N Ferrara Journal of Biological Chemistry 273 (46), 30336-30343, 1998 | 2687 | 1998 |
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation HP Gerber, TH Vu, AM Ryan, J Kowalski, Z Werb, N Ferrara Nature medicine 5 (6), 623-628, 1999 | 2633 | 1999 |
HIF-1α is essential for myeloid cell-mediated inflammation T Cramer, Y Yamanishi, BE Clausen, I Förster, R Pawlinski, N Mackman, ... Cell 112 (5), 645-657, 2003 | 2462 | 2003 |
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders LG Presta, H Chen, SJ O'Connor, V Chisholm, YG Meng, L Krummen, ... Cancer research 57 (20), 4593-4599, 1997 | 2448 | 1997 |
Molecular and biological properties of the vascular endothelial growth factor family of proteins N Ferrara, K Houck, LYN Jakeman, DW Leung Endocrine reviews 13 (1), 18-32, 1992 | 2312 | 1992 |
VEGF in signaling and disease: beyond discovery and development RS Apte, DS Chen, N Ferrara Cell 176 (6), 1248-1264, 2019 | 2098 | 2019 |
VEGF and the quest for tumour angiogenesis factors N Ferrara Nature Reviews Cancer 2 (10), 795-803, 2002 | 2053 | 2002 |
The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA KA Houck, N Ferrara, J Winer, G Cachianes, B Li, DW Leung Molecular endocrinology 5 (12), 1806-1814, 1991 | 1996 | 1991 |