John Christodoulou
John Christodoulou
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Mapping long-range interactions in α-synuclein using spin-label NMR and ensemble molecular dynamics simulations
MM Dedmon, K Lindorff-Larsen, J Christodoulou, M Vendruscolo, ...
Journal of the American Chemical Society 127 (2), 476-477, 2005
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
Cisplatin binding sites on human albumin
AI Ivanov, J Christodoulou, JA Parkinson, KJ Barnham, A Tucker, ...
Journal of Biological Chemistry 273 (24), 14721-14730, 1998
Multi-metal binding site of serum albumin
W Bal, J Christodoulou, PJ Sadler, A Tucker
Journal of inorganic biochemistry 70 (1), 33-39, 1998
Heat shock protein 70 inhibits α-synuclein fibril formation via preferential binding to prefibrillar species
MM Dedmon, J Christodoulou, MR Wilson, CM Dobson
Journal of Biological Chemistry 280 (15), 14733-14740, 2005
Structure and properties of a complex of α-synuclein and a single-domain camelid antibody
EJ De Genst, T Guilliams, J Wellens, EM O'day, CA Waudby, S Meehan, ...
Journal of molecular biology 402 (2), 326-343, 2010
Two-dimensional NMR lineshape analysis
CA Waudby, A Ramos, LD Cabrita, J Christodoulou
Scientific reports 6 (1), 24826, 2016
Cytochrome display on amyloid fibrils
AJ Baldwin, R Bader, J Christodoulou, CE MacPhee, CM Dobson, ...
Journal of the American Chemical Society 128 (7), 2162-2163, 2006
The interaction of αB-crystallin with mature α-synuclein amyloid fibrils inhibits their elongation
CA Waudby, TPJ Knowles, GL Devlin, JN Skepper, H Ecroyd, JA Carver, ...
Biophysical journal 98 (5), 843-851, 2010
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease
G Toth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ...
PloS one 9 (2), e87133, 2014
Protein folding on the ribosome
LD Cabrita, CM Dobson, J Christodoulou
Current opinion in structural biology 20 (1), 33-45, 2010
A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
J Gsponer, J Christodoulou, A Cavalli, JM Bui, B Richter, CM Dobson, ...
Structure 16 (5), 736-746, 2008
A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding
LD Cabrita, AME Cassaignau, HMM Launay, CA Waudby, T Wlodarski, ...
Nature Structural & Molecular Biology 23 (4), 278-285, 2016
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy
STD Hsu, P Fucini, LD Cabrita, H Launay, CM Dobson, J Christodoulou
Proceedings of the National Academy of Sciences 104 (42), 16516-16521, 2007
Chaperone proteostasis in Parkinson's disease: Stabilization of the Hsp70/α‐synuclein complex by Hip
C Roodveldt, CW Bertoncini, A Andersson, AT Van Der Goot, ST Hsu, ...
The EMBO journal 28 (23), 3758-3770, 2009
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbjörner, ...
Journal of molecular biology 425 (14), 2397-2411, 2013
Molecular determinants of the aggregation behavior of α‐and β‐synuclein
RC Rivers, JR Kumita, GG Tartaglia, MM Dedmon, A Pawar, ...
Protein Science 17 (5), 887-898, 2008
A New Structural Transition of Serum Albumin Dependent on the State of Cys34: Detection by 1H‐NMR Spectroscopy
J Christodoulou, PJ Sadler, A Tucker
European journal of biochemistry 225 (1), 363-368, 1994
On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with Congo red and lacmoid
C Lendel, CW Bertoncini, N Cremades, CA Waudby, M Vendruscolo, ...
Biochemistry 48 (35), 8322-8334, 2009
Immunological features of α‐synuclein in Parkinson's disease
C Roodveldt, J Christodoulou, CM Dobson
Journal of cellular and molecular medicine 12 (5b), 1820-1829, 2008
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