| Inhibition of the JAK/STAT pathway by ruxolitinib ameliorates thioacetamide-induced hepatotoxicity ME Shaker, SH Hazem, SA Ashamallah Food and Chemical Toxicology 96, 290-301, 2016 | 25 | 2016 |
| The novel Janus kinase inhibitor ruxolitinib confers protection against carbon tetrachloride-induced hepatotoxicity via multiple mechanisms SH Hazem, ME Shaker, SA Ashamallah, TM Ibrahim Chemico-Biological Interactions 220, 116-127, 2014 | 22 | 2014 |
| Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: Novel insights on autophagy, apoptosis, and pyroptosis R Abdelhady, S Saber, M Ahmed Abdel-Reheim, M Mohammad S. Alamri, ... Frontiers in Pharmacology 14, 1239025, 2023 | 16 | 2023 |
| Comparison of lactate and β-hydroxybutyrate in the treatment of concanavalin-A induced hepatitis SH Hazem, MF Hamed, MAA Saad, NM Gameil International Immunopharmacology 61, 376-384, 2018 | 14 | 2018 |
| Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-α/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced autoimmune hepatitis in mice M Elshal, SH Hazem Inflammopharmacology 30 (6), 2317-2329, 2022 | 8 | 2022 |
| Inhibition of Bruton tyrosine kinase by acalabrutinib dampens lipopolysaccharide/galactosamine-induced hepatic damage ME Shaker, HAM Gomaa, KS Alharbi, MM Al-Sanea, ME El-Mesery, ... Biomedicine & Pharmacotherapy 131, 110736, 2020 | 8 | 2020 |
| The NEDD8-activating enzyme inhibition with MLN4924 sensitizes human cancer cells of different origins to apoptosis and necroptosis M El-Mesery, MA Anany, SH Hazem, ME Shaker Archives of Biochemistry and Biophysics 691, 108513, 2020 | 8 | 2020 |
| Roflumilast extenuates inflammation and oxidative stress in cadmium-induced hepatic and testicular injury in rats NSS Aboulqassim, SH Hazem, MH Sharawy, GM Suddek International Immunopharmacology 124, 111027, 2023 | 3 | 2023 |
| The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice ME Shaker, OM Hendawy, M El-Mesery, SH Hazem International Immunopharmacology 103, 108463, 2022 | 3 | 2022 |
| STA9090 as a potential therapeutic agent for liver fibrosis by modulating the HSP90/TβRII/proteasome interplay: novel insights from in vitro and in vivo investigations OA Mohammed, MA Abdel-Reheim, MMS Alamri, J Alfaifi, MIE Adam, ... Pharmaceuticals 16 (8), 1080, 2023 | 2 | 2023 |
| WITHDRAWN: vinpocetine and Lactobacillus improve fatty liver in rats via modulating the oxidative stress, inflammation, adiponectin and gut microbiome AA Shaaban, EM Khalaf, SH Hazem, ME Shaker, A Shata, NA Nouh, ... Life Sciences 331, 121931, 2023 | 1 | 2023 |
| Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities ME Shaker, HAM Gomaa, MA Abdelgawad, M El-Mesery, AA Shaaban, ... International Immunopharmacology 120, 110373, 2023 | 1 | 2023 |
| Unveiling the therapeutic potential of exogenous beta-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis (vol 14, 1239025, 2023) R Abdelhady, S Saber, MA Abdel-Reheim, MMS Alamri, J Alfaifi, ... FRONTIERS IN PHARMACOLOGY 15, 2024 | | 2024 |
| Corrigendum: Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis R Abdelhady, S Saber, MA Abdel-Reheim, M Mohammad S. Alamri, ... Frontiers in Pharmacology 15, 1382529, 2024 | | 2024 |
| Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox … ME Shaker, HAM Goma, I Alsalahat, NAA Elkanzi, AA Azouz, ... Journal of Biomolecular Structure and Dynamics, 1-14, 2023 | | 2023 |
| Corrigendum: Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib ME Shaker, HAM Gomaa, SH Hazem, MA Abdelgawad, M El-Mesery, ... Frontiers in Pharmacology 14, 1281416, 2023 | | 2023 |
| Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib ME Shaker, HAM Gomaa, SH Hazem, MA Abdelgawad, M El-Mesery, ... Frontiers in Pharmacology 14, 1212771, 2023 | | 2023 |
Mohamed E. ShakerProfessor of Pharmacology & Toxicology, Faculty of Pharmacy, Mansoura UniversityVerified email at mans.edu.eg
